Follicular thyroid cancer staging

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Thyroid Cancer Main Page

Patient Information

Overview

Classification

Papillary Thyroid Cancer
Follicular Thyroid Cancer
Medullary Thyroid Cancer
Anaplastic Thyroid Cancer
Thyroid Lymphoma

Causes

Differential diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Staging


Thyroid TNM staging
Stage Description
TX Primary tumor cannot be assessed.
T0 No evidence of primary tumor.
T1 Tumor ≤2 cm in greatest dimension limited to the thyroid.
T1a Tumor ≤1 cm, limited to the thyroid.
T1b Tumor >1 cm but ≤2 cm in greatest dimension, limited to the thyroid.
T2 Tumor >2 cm but ≤4 cm in greatest dimension, limited to the thyroid.
T3 Tumor >4 cm in greatest dimension limited to the thyroid or any tumor with minimal extrathyroid extension (e.g., extension to sternothyroid muscle or perithyroid soft tissues).
T4a Moderately advanced disease.
Tumor of any size extending beyond the thyroid capsule to invade subcutaneous soft tissues, larynx, trachea, esophagus, or recurrent laryngeal nerve.
T4b Very advanced disease.
Tumor invades prevertebral fascia or encases carotid artery or mediastinal vessel.
T4a Intrathyroidal anaplastic carcinoma.
T4b Anaplastic carcinoma with gross extrathyroid extension.


Regional Lymph Nodes (N)
Stage Description
NX Regional lymph nodes cannot be assessed.
N0 No regional lymph node metastasis.
N1 Regional lymph node metastasis.
N1a Metastases to Level VI (pretracheal, paratracheal, and prelaryngeal/Delphian lymph nodes).
N1b Metastases to unilateral, bilateral, or contralateral cervical (Levels I, II, III, IV, or V) or retropharyngeal or superior mediastinal lymph nodes (Level VII).


Anatomic Stage/Prognostic Groups
Stage T N M
Papillary or follicular (differentiated)
YOUNGER THAN 45 YEARS
I Any T Any N M0
II Any T Any N M1
45 YEARS AND OLDER
I T1 Any N M1
II T2 N0 M0
III T3 N0 M0
T1 N1a M0
T2 N1a M0
T3 N1a M0
IVA T4a N0 M0
T4a N1a M0
T1 N1b M0
T2 N1b M0
T3 N1b M0
T4a N1b M0
IVB T4b Any N M0
Stage IVC Any T Any N M1
Distant Metastasis (M)
Stage Description
M0 No distant metastasis.
M1 Distant metastasis.