Follicular thyroid cancer staging
Thyroid Cancer Main Page |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Staging
Stage | Description |
---|---|
TX | Primary tumor cannot be assessed. |
T0 | No evidence of primary tumor. |
T1 | Tumor ≤2 cm in greatest dimension limited to the thyroid. |
T1a | Tumor ≤1 cm, limited to the thyroid. |
T1b | Tumor >1 cm but ≤2 cm in greatest dimension, limited to the thyroid. |
T2 | Tumor >2 cm but ≤4 cm in greatest dimension, limited to the thyroid. |
T3 | Tumor >4 cm in greatest dimension limited to the thyroid or any tumor with minimal extrathyroid extension (e.g., extension to sternothyroid muscle or perithyroid soft tissues). |
T4a | Moderately advanced disease. |
Tumor of any size extending beyond the thyroid capsule to invade subcutaneous soft tissues, larynx, trachea, esophagus, or recurrent laryngeal nerve. | |
T4b | Very advanced disease. |
Tumor invades prevertebral fascia or encases carotid artery or mediastinal vessel. | |
T4a | Intrathyroidal anaplastic carcinoma. |
T4b | Anaplastic carcinoma with gross extrathyroid extension. |
Stage | Description |
---|---|
NX | Regional lymph nodes cannot be assessed. |
N0 | No regional lymph node metastasis. |
N1 | Regional lymph node metastasis. |
N1a | Metastases to Level VI (pretracheal, paratracheal, and prelaryngeal/Delphian lymph nodes). |
N1b | Metastases to unilateral, bilateral, or contralateral cervical (Levels I, II, III, IV, or V) or retropharyngeal or superior mediastinal lymph nodes (Level VII). |
Stage | T | N | M |
---|---|---|---|
Papillary or follicular (differentiated) | |||
YOUNGER THAN 45 YEARS | |||
I | Any T | Any N | M0 |
II | Any T | Any N | M1 |
45 YEARS AND OLDER | |||
I | T1 | Any N | M1 |
II | T2 | N0 | M0 |
III | T3 | N0 | M0 |
T1 | N1a | M0 | |
T2 | N1a | M0 | |
T3 | N1a | M0 | |
IVA | T4a | N0 | M0 |
T4a | N1a | M0 | |
T1 | N1b | M0 | |
T2 | N1b | M0 | |
T3 | N1b | M0 | |
T4a | N1b | M0 | |
IVB | T4b | Any N | M0 |
Stage IVC | Any T | Any N | M1 |
Stage | Description |
---|---|
M0 | No distant metastasis. |
M1 | Distant metastasis. |