Multiple endocrine neoplasia type 1 MRI
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
MRI
Gastrointestinal Neuroendocrine Tumors
- Used for suspected hepatic, pancreatic or retroperitoneal NETS, often with gadolinium contrast.
- MRI enterography also possible.
Insulinoma
- Dynamic MRI with fast gradient echo sequences following bolus injection of contrast medium may aid the detection of these tumours[1]
- T1 C+ (Gd): typically shows enhancement, although contrast enhancement may not improve tumour visualisation compared with non-contrast images
Somatostatinoma
- Smaller lesions may be difficult to diagnose. Described signal characteristics of larger lesion include
- T1: low signal 1,8
- T2: high signal 1,8
- T1 (C+) Gd: most show early diffuse heterogenous enhancement
Reference
- ↑ Owen NJ, Sohaib SA, Peppercorn PD, Monson JP, Grossman AB, Besser GM; et al. (2001). "MRI of pancreatic neuroendocrine tumours". Br J Radiol. 74 (886): 968–73. doi:10.1259/bjr.74.886.740968. PMID 11675319.