Multiple endocrine neoplasia type 1 epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Epidemiology and Demographics
Prevalence
- Worldwide, the prevalence of Multiple endocrine neoplasia type 1 is estimated to be 2-3 per 100,000
- Multiple endocrine neoplasia type 1 is a rare disease that occurs in approximately one in 30,000 individuals.
Age
- Endocrine and non-endocrine manifestations of the disease in MEN1 patients most often begin in the fourth or fifth decade. The onset of the disease is rare before age 10 years.
Gender
- Men and women are affected equally by multiple endocrine neoplasia type 1.
- Males have a higher incidence of pancreatic tumors.
- Females have a higher incidence of pituitary tumors.
- Thymic tumors are found in men.