Barbexaclone

Barbexaclone

File:Barbexaclon Structural Formula V1.svg
Combination of
Phenobarbital	Barbiturate
Propylhexedrine	Stimulant (sympathomimetic)
[[{{{component3}}}]]	? Class
[[{{{component4}}}]]	? Class
[[{{{component5}}}]]	? Class
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	N03AA04 (WHO)
Identifiers
CAS Number	4388-82-3 Y
PubChem CID	71196
DrugBank	DB09001 N
ChemSpider	64332 Y
UNII	291GX1YB65
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
3D model (JSmol)	Interactive image
SMILES O=C1NC(=O)NC(=O)C1(c2ccccc2)CC.N(C)[C@@H](C)CC1CCCCC1
InChI InChI=1S/C12H12N2O3.C10H21N/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16;1-9(11-2)8-10-6-4-3-5-7-10/h3-7H,2H2,1H3,(H2,13,14,15,16,17);9-11H,3-8H2,1-2H3/t;9-/m.0/s1 Y Key:MJCBWPMBFCUHBP-NPULLEENSA-N Y
NY (what is this?)  (verify)

Barbexaclone (Maliasin) is a salt compound of phenobarbital and levopropylhexedrine. It was introduced in 1983. It has been reported to be as effective as phenobarbital but better tolerated; however, as of 2004, these "promising results" had not yet been confirmed nor denied in controlled trials. 100 mg of barbexaclone is equivalent to 60 mg of phenobarbital.

References

• The Treatment of Epilepsy 2nd Ed by S. D. Shorvon (Editor), David R. Fish (Editor), Emilio Perucca (Editor), W. Edwin Dodson (Editor). Published by Blackwell 2004. p. 472. ISBN 0-632-06046-8

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