IFNB1

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Interferon, beta 1, fibroblast
PDB rendering based on 1au1.
Available structures
PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB
Identifiers
Symbols IFNB1 ; IFB; IFF; IFNB; MGC96956
External IDs Template:OMIM5 Template:MGI HomoloGene1640
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Interferon, beta 1, fibroblast, also known as IFNB1, is a human gene.[1]


References

  1. "Entrez Gene: IFNB1 interferon, beta 1, fibroblast".

Further reading

  • Biron CA, Nguyen KB, Pien GC (2002). "Innate immune responses to LCMV infections: natural killer cells and cytokines". Curr. Top. Microbiol. Immunol. 263: 7–27. PMID 11987821.
  • Conti L, Fantuzzi L, Del Cornò M; et al. (2005). "Immunomodulatory effects of the HIV-1 gp120 protein on antigen presenting cells: implications for AIDS pathogenesis". Immunobiology. 209 (1–2): 99–115. PMID 15481145.
  • Bekisz J, Schmeisser H, Hernandez J; et al. (2005). "Human interferons alpha, beta and omega". Growth Factors. 22 (4): 243–51. doi:10.1080/08977190400000833. PMID 15621727.
  • Copeland KF (2006). "Modulation of HIV-1 transcription by cytokines and chemokines". Mini reviews in medicinal chemistry. 5 (12): 1093–101. PMID 16375755.
  • Silverman RH, Sengupta DN (1991). "Translational regulation by HIV leader RNA, TAT, and interferon-inducible enzymes". J. Exp. Pathol. 5 (2): 69–77. PMID 1708818.
  • Flores I, Mariano TM, Pestka S (1991). "Human interferon omega (omega) binds to the alpha/beta receptor". J. Biol. Chem. 266 (30): 19875–7. PMID 1834641.
  • May LT, Sehgal PB (1985). "On the relationship between human interferon alpha 1 and beta 1 genes". J. Interferon Res. 5 (3): 521–6. PMID 2414376.
  • Francois DT, Katona IM, June CH; et al. (1988). "Examination of the inhibitory and stimulatory effects of IFN-alpha, -beta, and -gamma on human B-cell proliferation induced by various B-cell mitogens". Clin. Immunol. Immunopathol. 48 (3): 297–306. PMID 3135963.
  • Conradt HS, Egge H, Peter-Katalinic J; et al. (1987). "Structure of the carbohydrate moiety of human interferon-beta secreted by a recombinant Chinese hamster ovary cell line". J. Biol. Chem. 262 (30): 14600–5. PMID 3667593.
  • Blank KJ, McKernan LN, Murasko DM (1985). "Poly I:C or IFN-alpha/beta treatment inhibits macrophage induced T cell proliferation". J. Interferon Res. 5 (1): 215–21. PMID 3872918.
  • Derynck R, Content J, DeClercq E; et al. (1980). "Isolation and structure of a human fibroblast interferon gene". Nature. 285 (5766): 542–7. PMID 6157094.
  • Taniguchi T, Ohno S, Fujii-Kuriyama Y, Muramatsu M (1980). "The nucleotide sequence of human fibroblast interferon cDNA". Gene. 10 (1): 11–5. PMID 6157601.
  • Houghton M, Easton MA, Stewart AG; et al. (1981). "The complete amino acid sequence of human fibroblast interferon as deduced using synthetic oligodeoxyribonucleotide primers of reverse transcriptase". Nucleic Acids Res. 8 (13): 2885–94. PMID 6159580.
  • Goeddel DV, Shepard HM, Yelverton E; et al. (1981). "Synthesis of human fibroblast interferon by E. coli". Nucleic Acids Res. 8 (18): 4057–74. PMID 6159584.
  • Houghton M, Stewart AG, Doel SM; et al. (1981). "The amino-terminal sequence of human fibroblast interferon as deduced from reverse transcripts obtained using synthetic oligonucleotide primers". Nucleic Acids Res. 8 (9): 1913–31. PMID 6159597.
  • Wetzel R (1981). "Assignment of the disulphide bonds of leukocyte interferon". Nature. 289 (5798): 606–7. PMID 6162107.
  • Lawn RM, Adelman J, Franke AE; et al. (1981). "Human fibroblast interferon gene lacks introns". Nucleic Acids Res. 9 (5): 1045–52. PMID 6164984.
  • Shepard HM, Leung D, Stebbing N, Goeddel DV (1982). "A single amino acid change in IFN-beta1 abolishes its antiviral activity". Nature. 294 (5841): 563–5. PMID 6171735.
  • Content J, De Wit L, Pierard D; et al. (1982). "Secretory proteins induced in human fibroblasts under conditions used for the production of interferon beta". Proc. Natl. Acad. Sci. U.S.A. 79 (9): 2768–72. PMID 6178110.
  • Fiers W, Remaut E, Devos R; et al. (1983). "The human fibroblast and human immune interferon genes and their expression in homologous and heterologous cells". Philos. Trans. R. Soc. Lond., B, Biol. Sci. 299 (1094): 29–38. PMID 6183692.

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