SLC22A11

Solute carrier family 22 (organic anion/cation transporter), member 11
Identifiers
Symbols	SLC22A11 ; MGC34282; OAT4; hOAT4
External IDs	Template:OMIM5 HomoloGene: 81863
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
File:PBB GE SLC22A11 220100 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Solute carrier family 22 (organic anion/cation transporter), member 11, also known as SLC22A11, is a human gene.

The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and is found mainly in the kidney and in the placenta, where it may act to prevent potentially harmful organic anions from reaching the fetus.

See also

• Solute carrier family

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cha SH, Sekine T, Kusuhara H; et al. (2000). "Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta". J. Biol. Chem. 275 (6): 4507–12. PMID 10660625.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sun W, Wu RR, van Poelje PD, Erion MD (2001). "Isolation of a family of organic anion transporters from human liver and kidney". Biochem. Biophys. Res. Commun. 283 (2): 417–22. doi:10.1006/bbrc.2001.4774. PMID 11327718.CS1 maint: Multiple names: authors list (link)
• Babu E, Takeda M, Narikawa S; et al. (2002). "Human organic anion transporters mediate the transport of tetracycline". Jpn. J. Pharmacol. 88 (1): 69–76. PMID 11855680.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kimura H, Takeda M, Narikawa S; et al. (2002). "Human organic anion transporters and human organic cation transporters mediate renal transport of prostaglandins". J. Pharmacol. Exp. Ther. 301 (1): 293–8. PMID 11907186.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Takeda M, Babu E, Narikawa S, Endou H (2002). "Interaction of human organic anion transporters with various cephalosporin antibiotics". Eur. J. Pharmacol. 438 (3): 137–42. PMID 11909604.CS1 maint: Multiple names: authors list (link)
• Enomoto A, Takeda M, Shimoda M; et al. (2002). "Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors". J. Pharmacol. Exp. Ther. 301 (3): 797–802. PMID 12023506.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Enomoto A, Kimura H, Chairoungdua A; et al. (2002). "Molecular identification of a renal urate anion exchanger that regulates blood urate levels". Nature. 417 (6887): 447–52. doi:10.1038/nature742. PMID 12024214.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhou F, Tanaka K, Pan Z; et al. (2004). "The role of glycine residues in the function of human organic anion transporter 4". Mol. Pharmacol. 65 (5): 1141–7. doi:10.1124/mol.65.5.1141. PMID 15102942.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhou F, Pan Z, Ma J, You G (2005). "Mutational analysis of histidine residues in human organic anion transporter 4 (hOAT4)". Biochem. J. 384 (Pt 1): 87–92. doi:10.1042/BJ20040751. PMID 15291761.CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhou F, Xu W, Hong M; et al. (2005). "The role of N-linked glycosylation in protein folding, membrane targeting, and substrate binding of human organic anion transporter hOAT4". Mol. Pharmacol. 67 (3): 868–76. doi:10.1124/mol.104.007583. PMID 15576633.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Taylor TD, Noguchi H, Totoki Y; et al. (2006). "Human chromosome 11 DNA sequence and analysis including novel gene identification". Nature. 440 (7083): 497–500. doi:10.1038/nature04632. PMID 16554811.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hagos Y, Stein D, Ugele B; et al. (2007). "Human renal organic anion transporter 4 operates as an asymmetric urate transporter". J. Am. Soc. Nephrol. 18 (2): 430–9. doi:10.1681/ASN.2006040415. PMID 17229912.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.