Stratifin

Stratifin
File:PBB Protein SFN image.jpg PDB rendering based on 1ywt.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1ywt​, 1yz5​
Identifiers
Symbols	SFN ; YWHAS
External IDs	Template:OMIM5 Template:MGI HomoloGene: 4475
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SFN 33322 i at tn.png
File:PBB GE SFN 33323 r at tn.png
File:PBB GE SFN 209260 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Stratifin, also known as SFN, is a human gene.

Further reading

• Hermeking H (2005). "Extracellular 14-3-3sigma protein: a potential mediator of epithelial-mesenchymal interactions". J. Invest. Dermatol. 124 (1): ix–x. doi:10.1111/j.0022-202X.2004.23534.x. PMID 15654940.
• Mhawech P (2005). "14-3-3 proteins--an update". Cell Res. 15 (4): 228–36. doi:10.1038/sj.cr.7290291. PMID 15857577.
• Lodygin D, Hermeking H (2005). "The role of epigenetic inactivation of 14-3-3sigma in human cancer". Cell Res. 15 (4): 237–46. doi:10.1038/sj.cr.7290292. PMID 15857578.
• Rasmussen HH, van Damme J, Puype M; et al. (1993). "Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes". Electrophoresis. 13 (12): 960–9. PMID 1286667.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Prasad GL, Valverius EM, McDuffie E, Cooper HL (1992). "Complementary DNA cloning of a novel epithelial cell marker protein, HME1, that may be down-regulated in neoplastic mammary cells". Cell Growth Differ. 3 (8): 507–13. PMID 1390337.CS1 maint: Multiple names: authors list (link)
• Leffers H, Madsen P, Rasmussen HH; et al. (1993). "Molecular cloning and expression of the transformation sensitive epithelial marker stratifin. A member of a protein family that has been involved in the protein kinase C signalling pathway". J. Mol. Biol. 231 (4): 982–98. doi:10.1006/jmbi.1993.1346. PMID 8515476.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hermeking H, Lengauer C, Polyak K; et al. (1998). "14-3-3 sigma is a p53-regulated inhibitor of G2/M progression". Mol. Cell. 1 (1): 3–11. PMID 9659898.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chan TA, Hermeking H, Lengauer C; et al. (1999). "14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage". Nature. 401 (6753): 616–20. doi:10.1038/44188. PMID 10524633.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Laronga C, Yang HY, Neal C, Lee MH (2000). "Association of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progression". J. Biol. Chem. 275 (30): 23106–12. doi:10.1074/jbc.M905616199. PMID 10767298.CS1 maint: Multiple names: authors list (link)
• Samuel T, Weber HO, Rauch P; et al. (2002). "The G2/M regulator 14-3-3sigma prevents apoptosis through sequestration of Bax". J. Biol. Chem. 276 (48): 45201–6. doi:10.1074/jbc.M106427200. PMID 11574543.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Johnson BA, Stehn JR, Yaffe MB, Blackwell TK (2002). "Cytoplasmic localization of tristetraprolin involves 14-3-3-dependent and -independent mechanisms". J. Biol. Chem. 277 (20): 18029–36. doi:10.1074/jbc.M110465200. PMID 11886850.CS1 maint: Multiple names: authors list (link)
• Tian H, Faje AT, Lee SL, Jorgensen TJ (2002). "Radiation-induced phosphorylation of Chk1 at S345 is associated with p53-dependent cell cycle arrest pathways". Neoplasia. 4 (2): 171–80. doi:10.1038/sj/neo/7900219. PMID 11896572.CS1 maint: Multiple names: authors list (link)
• Ku NO, Michie S, Resurreccion EZ; et al. (2002). "Keratin binding to 14-3-3 proteins modulates keratin filaments and hepatocyte mitotic progression". Proc. Natl. Acad. Sci. U.S.A. 99 (7): 4373–8. doi:10.1073/pnas.072624299. PMID 11917136.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Urano T, Saito T, Tsukui T; et al. (2002). "Efp targets 14-3-3 sigma for proteolysis and promotes breast tumour growth". Nature. 417 (6891): 871–5. doi:10.1038/nature00826. PMID 12075357.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Liu MY, Cai S, Espejo A; et al. (2002). "14-3-3 interacts with the tumor suppressor tuberin at Akt phosphorylation site(s)". Cancer Res. 62 (22): 6475–80. PMID 12438239.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bhatia K, Siraj AK, Hussain A; et al. (2003). "The tumor suppressor gene 14-3-3 sigma is commonly methylated in normal and malignant lymphoid cells". Cancer Epidemiol. Biomarkers Prev. 12 (2): 165–9. PMID 12582028.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kino T, Souvatzoglou E, De Martino MU; et al. (2003). "Protein 14-3-3sigma interacts with and favors cytoplasmic subcellular localization of the glucocorticoid receptor, acting as a negative regulator of the glucocorticoid signaling pathway". J. Biol. Chem. 278 (28): 25651–6. doi:10.1074/jbc.M302818200. PMID 12730237.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nakajima T, Shimooka H, Weixa P; et al. (2004). "Immunohistochemical demonstration of 14-3-3 sigma protein in normal human tissues and lung cancers, and the preponderance of its strong expression in epithelial cells of squamous cell lineage". Pathol. Int. 53 (6): 353–60. PMID 12787309.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rishi AK, Zhang L, Boyanapalli M; et al. (2003). "Identification and characterization of a cell cycle and apoptosis regulatory protein-1 as a novel mediator of apoptosis signaling by retinoid CD437". J. Biol. Chem. 278 (35): 33422–35. doi:10.1074/jbc.M303173200. PMID 12816952.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)