Silicosis differential diagnosis
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Malignant diseases Multiple pulmonary nodules that are ≥1 cm in diameter or detected by conventional chest radiography are most likely due to metastatic disease from a malignant solid organ primary tumor [1].[2]
●Multiple pulmonary nodules that are <5 mm in diameter, juxtaposed to either the visceral pleura or an interlobar fissure, and detected incidentally, are more likely to be benign lesions, such as granulomata, scars, or intraparenchymal lymph nodes [3] Mycobacterial infections[4]
Fungi – Multiple pulmonary nodules may be due to a fungal infection such as histoplasmosis, coccidioidomycosis, blastomycosis, or cryptococcosis. Invasive aspergillosis is likely in immunocompromised hosts. Nodules due to fungal infection tend to be 0.5 to 3 cm in diameter and do not have a predilection for a specific region of the lungs Both coal workers' pneumoconiosis and silicosis may evolve into progressive massive fibrosis or conglomerate masses
References
- ↑ Ginsberg MS, Griff SK, Go BD, Yoo HH, Schwartz LH, Panicek DM (1999). "Pulmonary nodules resected at video-assisted thoracoscopic surgery: etiology in 426 patients". Radiology. 213 (1): 277–82. doi:10.1148/radiology.213.1.r99oc08277. PMID 10540672.
- ↑ Gross BH, Glazer GM, Bookstein FL (1985). "Multiple pulmonary nodules detected by computed tomography: diagnostic implications". J Comput Assist Tomogr. 9 (5): 880–5. PMID 3861629.
- ↑ Ahn MI, Gleeson TG, Chan IH, McWilliams AM, Macdonald SL, Lam S; et al. (2010). "Perifissural nodules seen at CT screening for lung cancer". Radiology. 254 (3): 949–56. doi:10.1148/radiol.09090031. PMID 20177105.
- ↑ Fabreguet I, Francis F, Lemery M, Choudat L, Papo T, Sacre K (2009). "A 76-year-old man with multiple pulmonary nodules". Chest. 135 (4): 1094–7. doi:10.1378/chest.08-2049. PMID 19349406.