Silicosis differential diagnosis
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Malignant diseases Multiple pulmonary nodules that are ≥1 cm in diameter or detected by conventional chest radiography are most likely due to metastatic disease from a malignant solid organ primary tumor [1,2].
●Multiple pulmonary nodules that are <5 mm in diameter, juxtaposed to either the visceral pleura or an interlobar fissure, and detected incidentally, are more likely to be benign lesions, such as granulomata, scars, or intraparenchymal lymph nodes [1-3]. Mycobacterial infections Fungi – Multiple pulmonary nodules may be due to a fungal infection such as histoplasmosis, coccidioidomycosis, blastomycosis, or cryptococcosis. Invasive aspergillosis is likely in immunocompromised hosts. Nodules due to fungal infection tend to be 0.5 to 3 cm in diameter and do not have a predilection for a specific region of the lungs Both coal workers' pneumoconiosis and silicosis may evolve into progressive massive fibrosis or conglomerate masses