Small cell carcinoma of the lung staging
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Veterans Administration Lung Study Group (VALG) Staging
The Veterans Administration Lung Study Group (VALG) staging, also known as VA staging, is an old staging system that has been previously used in most clinical trials. Shown below is a table depicting the VA staging system which classifies SCLC into two stages.[1]
Stage | Characteristics |
Limited SCLC | Limited SCLC is characterized by the strict involvement of the ipsilateral lung. |
Extensive SCLC | Extensive SCLC extends beyond the ipsilateral lung and may involve the contralateral lung, or can be associated with pleural effusion, pericardial effusion, or hematogenous spread. |
American Joint Committee on Cancer (AJCC) Tumor, Node, and Metastasis (TNM) Staging
Shown below is a table summarizing the staging of lung cancer according to AJCC.[2]
For more information about the TNM staging, click here.
Stage | T | N | M |
Occult carcinoma | TX | N0 | M0 |
Stage 0 | Tis | N0 | M0 |
Stage IA | T1 | N0 | M0 |
Stage IB | T2 | N0 | M0 |
Stage IIA | T1 | N1 | M0 |
Stage IIB | T2 | N1 | M0 |
T3 | N0 | M0 | |
Stage IIIA | T1, T2 | N2 | M0 |
T3 | N1, N2 | M0 | |
Stage IIIB | Any T | N3 | M0 |
T4 | Any N | M0 | |
Stage IV | Any T | Any N | M1 |
National Comprehensive Cancer Network (NCCN) Staging
The National Comprehensive Cancer Network (NCCN) staging system combines the AJCC (TNM) staging with the VALG staging scheme. Although the AJCC staging scheme is newer than the VALG staging, clinicians commonly use the VALG staging system because it has been commonly referred to in clinical trials. Shown below is a table depicting the NCNN staging which classifies SCLC into two stages.[3]
References
- ↑ Micke P, Faldum A, Metz T, Beeh KM, Bittinger F, Hengstler JG; et al. (2002). "Staging small cell lung cancer: Veterans Administration Lung Study Group versus International Association for the Study of Lung Cancer--what limits limited disease?". Lung Cancer. 37 (3): 271–6. PMID 12234695.
- ↑ Shepherd FA, Crowley J, Van Houtte P, Postmus PE, Carney D, Chansky K; et al. (2007). "The International Association for the Study of Lung Cancer lung cancer staging project: proposals regarding the clinical staging of small cell lung cancer in the forthcoming (seventh) edition of the tumor, node, metastasis classification for lung cancer". J Thorac Oncol. 2 (12): 1067–77. doi:10.1097/JTO.0b013e31815bdc0d. PMID 18090577.
- ↑ NCCN Clinical Practice Guidelines in Oncology. Small Cell Lung Cancer, version 2.2014