Penicillin G potassium
| Penicillin G potassium |
|---|
| PENICILLIN G POTASSIUM® FDA Package Insert |
| Description |
| Clinical Pharmacology |
| Microbiology |
| Indications and Usage |
| Contraindications |
| Warnings and Precautions |
| Adverse Reactions |
| Overdosage |
| Dosage and Administration |
| How Supplied |
| Labels and Packages |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
Overview
Category
US Brand Names
PENICILLIN G POTASSIUM®
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Overdosage | Dosage and Administration | How Supplied | Labels and Packages
Mechanism of Action
Penicillin G is bactericidal against penicillin-susceptible microorganisms during the stage of active multiplication. It acts by inhibiting biosynthesis of cell-wall mucopeptide. It is not active against the penicillinase-producing bacteria, which include many strains of staphylococci. Penicillin G is highly active in vitro against staphylococci (except penicillinase-producing strains), streptococci (groups A, B, C, G, H, L and M), pneumococci and Nelsseriameningitidis. Other organisms susceptible in vitro to penicillin G are Nelsseriagonorrhoeae, Corynebacteriumdiphtheriae, Bacillus anthracis, clostridia, Actinomycesspecies, Spirillum minus, Streptobacillusmonillformis, Listeria monocytogenes, and leptospira; Treponemapallidumis extremely susceptible.[1]
References
- ↑ "PENICILLIN G POTASSIUM INJECTION, POWDER, FOR SOLUTION [SANDOZ INC]". Text " accessdate" ignored (help)
Adapted from the FDA Package Insert.