Middle East respiratory syndrome coronavirus infection history and symptoms: Difference between revisions
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The table describes the [[symptoms]] of [[MERS-CoV]] [[infection]]. All but two patients (96%) had one or more [[chronic disease|chronic medical conditions]], including [[diabetes]] (68%), [[hypertension]] (34%), [[heart disease]] (28%), and [[kidney disease]] (49%). Thirty-four (72%) had more than one [[chronic disease|chronic condition]]. In a retrospective study on 47 patients with [[MERS-CoV]] [[infection]], 42 (89%) needed [[intensive care]] and 34 (72%) had [[mechanical ventilation]].<ref name="pmid23891402">{{cite journal| author=Assiri A, Al-Tawfiq JA, Al-Rabeeah AA, Al-Rabiah FA, Al-Hajjar S, Al-Barrak A et al.| title=Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study. | journal=Lancet Infect Dis | year= 2013 | volume= 13 | issue= 9 | pages= 752-61 | pmid=23891402 | doi=10.1016/S1473-3099(13)70204-4 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23891402 }} </ref> Cases have been reported where patients developed [[acute renal failure]], [[pericarditis]] and [[disseminated intravascular coagulation ]]. <ref name="pmid23782859">{{cite journal| author=Drosten C, Seilmaier M, Corman VM, Hartmann W, Scheible G, Sack S et al.| title=Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection. | journal=Lancet Infect Dis | year= 2013 | volume= 13 | issue= 9 | pages= 745-51 | pmid=23782859 | doi=10.1016/S1473-3099(13)70154-3 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23782859 }} </ref> | The table describes the [[symptoms]] of [[MERS-CoV]] [[infection]]. All but two patients (96%) had one or more [[chronic disease|chronic medical conditions]], including [[diabetes]] (68%), [[hypertension]] (34%), [[heart disease]] (28%), and [[kidney disease]] (49%). Thirty-four (72%) had more than one [[chronic disease|chronic condition]]. In a retrospective study on 47 patients with [[MERS-CoV]] [[infection]], 42 (89%) needed [[intensive care]] and 34 (72%) had [[mechanical ventilation]].<ref name="pmid23891402">{{cite journal| author=Assiri A, Al-Tawfiq JA, Al-Rabeeah AA, Al-Rabiah FA, Al-Hajjar S, Al-Barrak A et al.| title=Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study. | journal=Lancet Infect Dis | year= 2013 | volume= 13 | issue= 9 | pages= 752-61 | pmid=23891402 | doi=10.1016/S1473-3099(13)70204-4 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23891402 }} </ref> Cases have been reported where patients developed [[acute renal failure]], [[pericarditis]] and [[disseminated intravascular coagulation ]]. <ref name="pmid23782859">{{cite journal| author=Drosten C, Seilmaier M, Corman VM, Hartmann W, Scheible G, Sack S et al.| title=Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection. | journal=Lancet Infect Dis | year= 2013 | volume= 13 | issue= 9 | pages= 745-51 | pmid=23782859 | doi=10.1016/S1473-3099(13)70154-3 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23782859 }} </ref> | ||
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Revision as of 15:27, 20 June 2014
Middle East Respiratory Syndrome Coronavirus Infection Microchapters |
Differentiating Middle East Respiratory Syndrome Coronavirus Infection from other Diseases |
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Middle East respiratory syndrome coronavirus infection history and symptoms On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
The most common symptoms at presentation include fever, with or without chills or rigors, cough, shortness of breath, and myalgia. Gastrointestinal symptoms such as diarrhea, vomiting, or abdominal pain are also frequent. Acute kidney injury, pericarditis, and disseminated intravascular coagulation and other serious complications may occur in some cases.
History and Symptoms
Criteria for Suspected Case of MERS-CoV Infection
Patients should meet the following criteria, either A or B | |
A. Fever (≥38°C, 100.4°F) and pneumonia or acute respiratory distress syndrome (based on clinical or radiological evidence) | B. Fever (≥38°C, 100.4°F) |
AND EITHER | AND |
• History of travel from countries in or near the Arabian Peninsula within 14 days before symptom onset | • Symptoms of respiratory illness (not necessarily pneumonia; e.g., cough, shortness of breath) |
OR | AND |
• Close contact with a symptomatic traveler who developed fever and acute respiratory illness (not necessarily pneumonia) within 14 days after traveling from countries in or near the Arabian Peninsula | • Being in a healthcare facility (as a patient, worker, or visitor) within 14 days before symptom onset in a country or territory in or near the Arabian Peninsula in which recent healthcare-associated cases of MERS have been identified |
OR | |
• Member of a cluster of patients with severe acute respiratory illness (e.g.fever and pneumonia requiring hospitalization) of unknown etiology in which MERS-CoV is being evaluated, in consultation with state and local health departments | |
Table adapted from CDC-MERS-Interim Guidance [1] |
Symptoms
The table describes the symptoms of MERS-CoV infection. All but two patients (96%) had one or more chronic medical conditions, including diabetes (68%), hypertension (34%), heart disease (28%), and kidney disease (49%). Thirty-four (72%) had more than one chronic condition. In a retrospective study on 47 patients with MERS-CoV infection, 42 (89%) needed intensive care and 34 (72%) had mechanical ventilation.[2] Cases have been reported where patients developed acute renal failure, pericarditis and disseminated intravascular coagulation . [3]
Symptom | Percentage |
---|---|
Fever Fever with chills or rigors |
98% 87% |
Cough Dry Productive |
83% 47% 36% |
Hemoptysis | 17% |
Shortness of breath | 72% |
Chest Pain | 15% |
Sore throat | 21% |
Runny nose | 4% |
Abdominal Pain | 17% |
Nausea | 21% |
Vomiting | 21% |
Diarrhoea | 26% |
Myalgia | 32% |
Headache | 13% |
References
- ↑ “CDC-MERS-Interim Guidance.” Accessed June 20, 2014. http://www.cdc.gov/coronavirus/mers/interim-guidance.html.
- ↑ Assiri A, Al-Tawfiq JA, Al-Rabeeah AA, Al-Rabiah FA, Al-Hajjar S, Al-Barrak A; et al. (2013). "Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study". Lancet Infect Dis. 13 (9): 752–61. doi:10.1016/S1473-3099(13)70204-4. PMID 23891402.
- ↑ Drosten C, Seilmaier M, Corman VM, Hartmann W, Scheible G, Sack S; et al. (2013). "Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection". Lancet Infect Dis. 13 (9): 745–51. doi:10.1016/S1473-3099(13)70154-3. PMID 23782859.