Rifampin isoniazid: Difference between revisions
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==Overview== | ==Overview== | ||
''Rifampicin''' ([[International Nonproprietary Name|INN]]) {{IPAc-en|r|ɪ|ˈ|f|æ|m|p|ə|s|ɪ|n}} or '''rifampin''' ([[United States Adopted Name|USAN]]) is a [[bactericidal]] [[antibiotic]] drug of the [[rifamycin]] group.<ref name="isbn0-07-142290-0">{{cite book |author=Masters, Susan B.; Trevor, Anthony J.; Katzung, Bertram G. |title=Katzung & Trevor's pharmacology |publisher=Lange Medical Books/McGraw Hill, Medical Pub. Division |location=New York |year=2005 |pages= |isbn=0-07-142290-0 |oclc= |doi= |accessdate=}}</ref> | |||
Rifampicin inhibits bacterial DNA-dependent RNA synthesis by inhibiting bacterial DNA-dependent [[RNA polymerase]].<ref name="Calvori" | |||
It is a semisynthetic compound derived from ''Amycolatopsis rifamycinica '' (formerly known as ''Amycolatopsis mediterranei'' and ''Streptomyces mediterranei'').<ref>{{cite journal|author=Sensi P, Margalith P, Timbal MT|title=Rifomycin, a new antibiotic—preliminary report|journal=Farmaco Ed Sci|year=1959|volume=14|pages=146–147}}</ref> Rifampicin may be abbreviated '''R''', '''RMP''', '''RA''', '''RF''', or '''RIF''' (US | |||
==Category== | ==Category== | ||
Revision as of 02:28, 5 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chetan Lokhande, M.B.B.S [2]
Overview
Rifampicin' (INN) /rɪˈfæmpəsɪn/ or rifampin (USAN) is a bactericidal antibiotic drug of the rifamycin group.[1]
Rifampicin inhibits bacterial DNA-dependent RNA synthesis by inhibiting bacterial DNA-dependent RNA polymerase. Rifampicin may be abbreviated R, RMP, RA, RF, or RIF (US
Category
Antimycobacterial
US Brand Names
RIFAMATE®
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Overdosage | Clinical Studies | Dosage and Administration | Compatibility, Reconstitution, and Stability | Directions For Use | How Supplied | Labels and Packages
Mechanisms of Action
References
- ↑ Masters, Susan B.; Trevor, Anthony J.; Katzung, Bertram G. (2005). Katzung & Trevor's pharmacology. New York: Lange Medical Books/McGraw Hill, Medical Pub. Division. ISBN 0-07-142290-0.