Mumps overview: Difference between revisions

Jump to navigation Jump to search
No edit summary
Line 1: Line 1:
__NOTOC__
{{Mumps}}
{{Mumps}}
{{CMG}}; {{AOEIC}} {{LG}}
{{CMG}}; {{AOEIC}} {{LG}}
Line 19: Line 20:
*Travelers who are older than 12 months and who do not have evidence of mumps immunity.
*Travelers who are older than 12 months and who do not have evidence of mumps immunity.
*[[Immunodeficiency|Immunodeficiency states]]
*[[Immunodeficiency|Immunodeficiency states]]
==Complications==
While symptoms are generally not severe in children, the symptoms in teenagers and adults can be more severe and complications such as [[infertility]] or [[subfertility]] are relatively common, although still rare in absolute terms.<ref>{{cite journal | author=Preveden T, Jovanovic J, Ristic D | title=[Fertility in men after mumps infection without manifestations of orchitis] | journal=Med Pregl | year=1996 | pages=99-102 | volume=49 | issue=3-4 | id={{PMID|8692089}} }}</ref><sup> </sup><ref>{{cite journal | author=Shakhov EV, Krupin VN | title=[The clinico-statistical characteristics of the testicular generative function in male subfertility following mumps] | journal=Urol Nefrol (Mosk) | year=1990 | pages=46-50 | volume= | issue=2 | id={{PMID|2368216}} }}</ref><sup> </sup><ref>{{cite journal | author=Tsvetkov D | title=[Spermatological disorders in patients with postmumps orchitis] | journal=Akush Ginekol (Sofiia) | year=1990 | pages=46-9 | volume=29 | issue=6 | id={{PMID|2100952}} }}</ref>


==Diagnosis==
==Diagnosis==
Line 38: Line 41:
==Treatment==
==Treatment==
Currently, there is no specific treatment for mumps. In addition, the disease itself is generally self-limiting, and runs its course before waning. Supportive care with [[analgesics]] may provide symptomatic benefit.
Currently, there is no specific treatment for mumps. In addition, the disease itself is generally self-limiting, and runs its course before waning. Supportive care with [[analgesics]] may provide symptomatic benefit.
==Complications==
While symptoms are generally not severe in children, the symptoms in teenagers and adults can be more severe and complications such as [[infertility]] or [[subfertility]] are relatively common, although still rare in absolute terms.<ref>{{cite journal | author=Preveden T, Jovanovic J, Ristic D | title=[Fertility in men after mumps infection without manifestations of orchitis] | journal=Med Pregl | year=1996 | pages=99-102 | volume=49 | issue=3-4 | id={{PMID|8692089}} }}</ref><sup> </sup><ref>{{cite journal | author=Shakhov EV, Krupin VN | title=[The clinico-statistical characteristics of the testicular generative function in male subfertility following mumps] | journal=Urol Nefrol (Mosk) | year=1990 | pages=46-50 | volume= | issue=2 | id={{PMID|2368216}} }}</ref><sup> </sup><ref>{{cite journal | author=Tsvetkov D | title=[Spermatological disorders in patients with postmumps orchitis] | journal=Akush Ginekol (Sofiia) | year=1990 | pages=46-9 | volume=29 | issue=6 | id={{PMID|2100952}} }}</ref>
==References==
==References==
{{reflist|2}}
{{reflist|2}}
Line 52: Line 51:
[[Category:Pediatrics]]
[[Category:Pediatrics]]
[[Category:Dermatology]]
[[Category:Dermatology]]
[[Category:Viral diseases]]
[[Category:Oral pathology]]
[[Category:Mononegavirales]]
[[Category:Mature chapter]]
[[Category:Overview complete]]

Revision as of 19:16, 20 November 2012

Mumps Microchapters

Home

Patient Information

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Mumps from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

CT

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Mumps overview On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Mumps overview

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Mumps overview

CDC on Mumps overview

Mumps overview in the news

Blogs on Mumps overview

Directions to Hospitals Treating Mumps

Risk calculators and risk factors for Mumps overview

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Lakshmi Gopalakrishnan, M.B.B.S. [2]

Overview

Mumps is a highly contagious viral disease that leads to painful swelling of the salivary glands and is caused by the mumps virus. Mumps is spread through direct contact with an infected person. Symptoms include fever, glandular swelling, headache, sore throat, and orchitis. Mumps is a self-limiting disease, and the prognosis is generally good, even if other organs are involved.

Pathophysiology

Mumps is caused by paramyxovirus and is spread via inhalation of droplet or through direct contact with an infected person. The incubation period is usually 15-20 days.

Epidemiology

Developed countries:

Before the routine vaccination program was introduced in the United States, mumps was a common illness in infants, children and young adults. Because most people have now been vaccinated, mumps has become a rare disease in the United States.

Developing countries:

Mumps still remains a significant threat to health among pediatric population in the developing countries.[1]

Risk factors

  • Anyone who is not immune from either previous mumps infection or from vaccination can get mumps.
  • Travelers who are older than 12 months and who do not have evidence of mumps immunity.
  • Immunodeficiency states

Complications

While symptoms are generally not severe in children, the symptoms in teenagers and adults can be more severe and complications such as infertility or subfertility are relatively common, although still rare in absolute terms.[2] [3] [4]

Diagnosis

Symptoms:

  • Approximately 20-30% cases infected with mumps may remain asymptomatic.[5]

Physical examination:

  • Presence of swollen salivary glands, particularly parotid gland is characteristic of mumps.

Lab tests:

  • Laboratory testing for mumps virus can be useful, and may include virus isolation from swabs of affected salivary ducts, antigen detection by PCR, and serologic testing for IgM antibody or a significant rise in IgG antibody. However, there are many important caveats to be aware of when interpreting the results.[7]

Treatment

Currently, there is no specific treatment for mumps. In addition, the disease itself is generally self-limiting, and runs its course before waning. Supportive care with analgesics may provide symptomatic benefit.

References

  1. Kasper DL, Braunwald E, Fauci AS, Hauser SL, Longo DL, Jameson JL, Isselbacher KJ, Eds. (2004). Harrison's Principles of Internal Medicine (16th ed.). McGraw-Hill Professional. ISBN 0-07-140235-7.
  2. Preveden T, Jovanovic J, Ristic D (1996). "[Fertility in men after mumps infection without manifestations of orchitis]". Med Pregl. 49 (3–4): 99–102. PMID 8692089.
  3. Shakhov EV, Krupin VN (1990). "[The clinico-statistical characteristics of the testicular generative function in male subfertility following mumps]". Urol Nefrol (Mosk) (2): 46–50. PMID 2368216.
  4. Tsvetkov D (1990). "[Spermatological disorders in patients with postmumps orchitis]". Akush Ginekol (Sofiia). 29 (6): 46–9. PMID 2100952.
  5. "Mumps epidemic--Iowa, 2006". MMWR. Morbidity and Mortality Weekly Report. 55 (13): 366–8. 2006. PMID 16601665. Retrieved 2012-03-08. Unknown parameter |month= ignored (help)
  6. Enders G (1996). Paramyxoviruses–Mumps virus. In: Barron's Medical Microbiology (Barron S et al, eds.) (4th ed. ed.). Univ of Texas Medical Branch. (via NCBI Bookshelf) ISBN 0-9631172-1-1.
  7. "Mumps: Lab Testing for Mumps Infection". Centers for Disease Control and Prevention. 13 April 2010. Retrieved 30 October 2011.
  8. Skrha J, Stĕpán J, Sixtová E (1979). "Amylase isoenzymes in mumps". European Journal of Pediatrics. 132 (2): 99–105. PMID 499265. Unknown parameter |month= ignored (help); |access-date= requires |url= (help)


Template:WikiDoc Sources