Systemic lupus erythematosus epidemiology and demographics

Systemic lupus erythematosus Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Raviteja Guddeti, M.B.B.S. [3]

Epidemiology

Prevalence

• Worldwide, a conservative estimate states that over 5 million people have lupus.
• In the United States the prevalence of the disease is 25 per every 100,000. In the United States alone, it is estimated that between 270,000 and 1.5 million people have lupus, making it more common than cystic fibrosis or cerebral palsy.

Age

• The prevalence of the disease is common in the young patient population even though it can occur at any age.

Gender

• Lupus occurs in both men and women but young women of the childbearing age are nine times more often diagnosed than men.

Race

• The disease appears to be more prevalent in women of African, Asian, Hispanic and Native American origin but this may be due to socioeconomic factors.
• SLE occurs with much greater severity among African-American women, who suffer more severe symptoms as well as a higher mortality rate.