Alagille syndrome natural history: Difference between revisions

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Revision as of 18:30, 17 April 2012

Alagille syndrome Microchapters

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Overview

Historical Perspective

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Risk Factors

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Differentiating Alagille syndrome from other Diseases

Natural History, Complications & Prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The prognosis for Alagille syndrome patients varies largely on choice of treatment.

Prognosis

Mortality is approximately 10%, with vascular accidents, cardiac disease, and liver disease accounting for most of the deaths. Vascular anomalies account for 34% of the mortality in this population [1].

References

  1. Kamath BM, Spinner NB, Emerick KM, Chudley AE, Booth C, Piccoli DA; et al. (2004). "Vascular anomalies in Alagille syndrome: a significant cause of morbidity and mortality". Circulation. 109 (11): 1354–8. doi:10.1161/01.CIR.0000121361.01862.A4. PMID 14993126.

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