Alagille syndrome MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

The cerebral vasculopathy of Alagille syndrome predominantly involves the internal carotid arteries. It is more prevalent than would be suggested by the number of symptomatic individuals, appears to be progressive and shares many similarities with moyamoya. Magnetic resonance imaging with angiography is useful to detect these lesions and may have a valuable role in screening for treatable lesions such as aneurysms [1].

References

  1. Emerick KM, Krantz ID, Kamath BM, Darling C, Burrowes DM, Spinner NB; et al. (2005). "Intracranial vascular abnormalities in patients with Alagille syndrome". J Pediatr Gastroenterol Nutr. 41 (1): 99–107. PMID 15990638.

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