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==Differential Diagnosis==
==Differential Diagnosis==


*Several [[medical conditions]] can mimic [[eczema]], with overlapping features. These conditions could be due to an [[inflammatory]], [[infectious]], [[immunodeficiency]], or a [[nutritional deficiency]] problem.  
*Several [[medical conditions]] can mimic [[eczema]], with overlapping features. These conditions could be due to an [[inflammation]], [[neoplasm]], [[immunodeficiency]], or a [[nutritional deficiency]] problem.  
*Table 1 summarizes these [[medical conditions]], with their corresponding expected time of presentations.
*Table 1 summarizes these [[medical conditions]], with their corresponding expected time of presentations.


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{| style="border: 0px; font-size: 90%; margin: 1px; width: " align="center" 1000px;"
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|+<big>''' Table 1. [[Differential Diagnosis]] of [[Eczema]].'''</big>
|+<big>''' Table 1. [[Differential Diagnosis]] of [[Eczema]].'''</big><ref name="pmidhttps://doi.org/10.3390/jcm4050884">{{cite journal| author=Schmoldt A, Benthe HF, Haberland G| title=Digitoxin metabolism by rat liver microsomes. | journal=Biochem Pharmacol | year= 1975 | volume= 24 | issue= 17 | pages= 1639-41 | pmid=https://doi.org/10.3390/jcm4050884 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10  }} </ref>
! align="center" style="background: #00CED1; width: 150px;" |{{fontcolor|#FFF|Type}}
! align="center" style="background: #00CED1; width: 150px;" |{{fontcolor|#FFF|Type}}
! align="center" style="background: #00CED1; width: 150px;" |{{fontcolor|#FFF|Medical Condition}}
! align="center" style="background: #00CED1; width: 150px;" |{{fontcolor|#FFF|Medical Condition}}
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| style="padding: 2px 2px; background: #F5F5F5;" |
| style="padding: 2px 2px; background: #F5F5F5;" |
*[[Morbiliform rash]]
*[[Morbiliform rash]]
| style="padding: 2px 2px; background: #F5F5F5;" |[[Infancy]]
| style="padding: 2px 2px; background: #F5F5F5;" |[[Infancy]].
|-
|-
| align="left" style="padding: 2px 2px; background: #F5F5F5;" |[[Contact Dermatitis]
| align="left" style="padding: 2px 2px; background: #F5F5F5;" |[[Contact Dermatitis]]
| style="padding: 2px 2px; background: #F5F5F5;" |
| style="padding: 2px 2px; background: #F5F5F5;" |
*[[Vesicular]] and [[pruritic]].
*[[Vesicular]] and [[pruritic]].
| style="padding: 2px 2px; background: #F5F5F5;" |[[Infancy]]
| style="padding: 2px 2px; background: #F5F5F5;" |[[Infancy]].
|-
 
| rowspan="1" align="center" style="padding: 2px 2px; background: #E6E6FA; font-weight: bold" |[[Neoplastic]]
| align="left" style="padding: 2px 2px; background: #F5F5F5;" |[[Cutaneous T-cell Lymphoma]]
| style="padding: 2px 2px; background: #F5F5F5;" |
*[[Eczematous]] [[patch]].
*[[Resistant]] to [[topical steroids]].
| style="padding: 2px 2px; background: #F5F5F5;" |[[Adulthood]].
|-
 
| rowspan="4" align="center" style="padding: 2px 2px; background: #E6E6FA; font-weight: bold" |[[Immunodeficiency]]
| align="left" style="padding: 2px 2px; background: #F5F5F5;" |[[Wiskott-Aldrich Syndrome]]
| style="padding: 2px 2px; background: #F5F5F5;" |
*[[Recurrent infections]], [[failure to thrive]], and resistant to [[topical steroids]].
| style="padding: 2px 2px; background: #F5F5F5;" |[[Infancy]].
|-
| align="left" style="padding: 2px 2px; background: #F5F5F5;" |[[Netherton syndrome]]
| style="padding: 2px 2px; background: #F5F5F5;" |
*[[Recurrent infections]], [[failure to thrive]], and resistant to [[topical steroids]].
| style="padding: 2px 2px; background: #F5F5F5;" |[[Infancy]].
|-
| align="left" style="padding: 2px 2px; background: #F5F5F5;" |[[Hyper IgE syndrome]]
*[[Recurrent infections]], [[failure to thrive]], and resistant to [[topical steroids]].
| style="padding: 2px 2px; background: #F5F5F5;" |[[Infancy]].
|-
| align="left" style="padding: 2px 2px; background: #F5F5F5;" |[[DOCK8]]
*[[Recurrent infections]], [[failure to thrive]], and resistant to [[topical steroids]].
| style="padding: 2px 2px; background: #F5F5F5;" |[[Infancy]].
|-
|-




| rowspan="2" align="center" style="padding: 2px 2px; background: #E6E6FA; font-weight: bold" |[[Nutritional Deficiency]]
| align="left" style="padding: 2px 2px; background: #F5F5F5;" |[[Zinc]]
| style="padding: 2px 2px; background: #F5F5F5;" |
*[[Weight loss]].
| style="padding: 2px 2px; background: #F5F5F5;" |[[Infancy]] to [[early childhood]].
|-
| align="left" style="padding: 2px 2px; background: #F5F5F5;" |[[Biotin]]
| style="padding: 2px 2px; background: #F5F5F5;" |
*[[Failure to thrive]].
| style="padding: 2px 2px; background: #F5F5F5;" |[[Infancy]] to [[early childhood]].
|-
|}
|}


Revision as of 02:33, 18 May 2022

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Edzel Lorraine Co, D.M.D., M.D.

Overview

Several medical conditions can mimic eczema, with overlapping features. These conditions could be due to an inflammatory, infectious, immunodeficiency, or a nutritional deficiency problem. It is important to differentiate one from another to render proper medical treatment.[1]


Differential Diagnosis


 Table 1. Differential Diagnosis of Eczema.[1]
Type Medical Condition Manifestations Expected Time of Presentation
Inflammatory Psoriasis Adolescence to adulthood.
Viral Exanthem Infancy.
Contact Dermatitis Infancy.
Neoplastic Cutaneous T-cell Lymphoma Adulthood.
Immunodeficiency Wiskott-Aldrich Syndrome Infancy.
Netherton syndrome Infancy.
Hyper IgE syndrome Infancy.
DOCK8 Infancy.
Nutritional Deficiency Zinc Infancy to early childhood.
Biotin Infancy to early childhood.

References

  1. ↑ 1.0 1.1 Schmoldt A, Benthe HF, Haberland G (1975). "Digitoxin metabolism by rat liver microsomes". Biochem Pharmacol. 24 (17): 1639–41. PMID https://doi.org/10.3390/jcm4050884 Check |pmid= value (help).
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