Sexcord/ stromal ovarian tumors natural history, complications and prognosis: Difference between revisions
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===Prognosis=== | ===Prognosis=== | ||
*Depending on the extent of the tumor at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as excellent<ref name="pmid16050568">{{cite journal |vauthors=Schneider DT, Calaminus G, Harms D, Göbel U |title=Ovarian sex cord-stromal tumors in children and adolescents |journal=J Reprod Med |volume=50 |issue=6 |pages=439–46 |date=June 2005 |pmid=16050568 |doi= |url=}}</ref><ref name="pmid24416992">{{cite journal |vauthors=Elashry R, Hemida R, Goda H, Abdel-Hady el-S |title=Prognostic factors of germ cell and sex cord-stromal ovarian tumors in pediatric age: 5 years experience |journal=J. Exp. Ther. Oncol. |volume=10 |issue=3 |pages=181–7 |date=2013 |pmid=24416992 |doi= |url=}}</ref><ref name="pmid15285297">{{cite journal |vauthors=Zanagnolo V, Pasinetti B, Sartori E |title=Clinical review of 63 cases of sex cord stromal tumors |journal=Eur. J. Gynaecol. Oncol. |volume=25 |issue=4 |pages=431–8 |date=2004 |pmid=15285297 |doi= |url=}}</ref> | *Depending on the extent of the tumor at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as excellent<ref name="pmid16050568">{{cite journal |vauthors=Schneider DT, Calaminus G, Harms D, Göbel U |title=Ovarian sex cord-stromal tumors in children and adolescents |journal=J Reprod Med |volume=50 |issue=6 |pages=439–46 |date=June 2005 |pmid=16050568 |doi= |url=}}</ref><ref name="pmid24416992">{{cite journal |vauthors=Elashry R, Hemida R, Goda H, Abdel-Hady el-S |title=Prognostic factors of germ cell and sex cord-stromal ovarian tumors in pediatric age: 5 years experience |journal=J. Exp. Ther. Oncol. |volume=10 |issue=3 |pages=181–7 |date=2013 |pmid=24416992 |doi= |url=}}</ref><ref name="pmid15285297">{{cite journal |vauthors=Zanagnolo V, Pasinetti B, Sartori E |title=Clinical review of 63 cases of sex cord stromal tumors |journal=Eur. J. Gynaecol. Oncol. |volume=25 |issue=4 |pages=431–8 |date=2004 |pmid=15285297 |doi= |url=}}</ref><ref name="ZhangCheung2007">{{cite journal|last1=Zhang|first1=Mallory|last2=Cheung|first2=Michael K.|last3=Shin|first3=Jacob Y.|last4=Kapp|first4=Daniel S.|last5=Husain|first5=Amreen|last6=Teng|first6=Nelson N.|last7=Berek|first7=Jonathan S.|last8=Osann|first8=Kathryn|last9=Chan|first9=John K.|title=Prognostic factors responsible for survival in sex cord stromal tumors of the ovary—An analysis of 376 women|journal=Gynecologic Oncology|volume=104|issue=2|year=2007|pages=396–400|issn=00908258|doi=10.1016/j.ygyno.2006.08.032}}</ref> | ||
*Most sexcord-stromal ovarian tumors present at a low tumor stage and also prognosis in these patients is excellent | *Most sexcord-stromal ovarian tumors present at a low tumor stage and also prognosis in these patients is excellent | ||
*Patients with juvinile granulosa cell tumors(JGCT) and sertoli-Leydig cell tumors (SLCTs) show greater mitotic activity than all other histologic types | *Patients with juvinile granulosa cell tumors(JGCT) and sertoli-Leydig cell tumors (SLCTs) show greater mitotic activity than all other histologic types |
Revision as of 17:18, 9 April 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
OR
Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
OR
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of sexcord/ stromal ovarian tumors usually develop in the second/ third/ fourth decade of life, and start with symptoms such as:
- Adnexal mass
- Abdominal & pelvic symptoms
- Bloating
- Urinary urgency or frequency
- Dysphagia(difficulty eating) or feeling full quickly
- Pelvic or abdominal pain
- If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
Complications
- Common complications of [disease name] include:
- [Complication 1]
- [Complication 2]
- [Complication 3]
Prognosis
- Depending on the extent of the tumor at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as excellent[1][2][3][4]
- Most sexcord-stromal ovarian tumors present at a low tumor stage and also prognosis in these patients is excellent
- Patients with juvinile granulosa cell tumors(JGCT) and sertoli-Leydig cell tumors (SLCTs) show greater mitotic activity than all other histologic types
- Inturn high mitotic activity is associated with adverse outcome
- The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
- [Subtype of disease/malignancy] is associated with the most favorable prognosis.
- The prognosis varies with the subtypes of tumor[2]
- Sertoli-Leydig cell tumors have a 70 to 90 percent five-year survival overall and is mainly related to the stage and degree of histologic differentiation.
References
- ↑ Schneider DT, Calaminus G, Harms D, Göbel U (June 2005). "Ovarian sex cord-stromal tumors in children and adolescents". J Reprod Med. 50 (6): 439–46. PMID 16050568.
- ↑ 2.0 2.1 Elashry R, Hemida R, Goda H, Abdel-Hady e (2013). "Prognostic factors of germ cell and sex cord-stromal ovarian tumors in pediatric age: 5 years experience". J. Exp. Ther. Oncol. 10 (3): 181–7. PMID 24416992. Vancouver style error: initials (help)
- ↑ Zanagnolo V, Pasinetti B, Sartori E (2004). "Clinical review of 63 cases of sex cord stromal tumors". Eur. J. Gynaecol. Oncol. 25 (4): 431–8. PMID 15285297.
- ↑ Zhang, Mallory; Cheung, Michael K.; Shin, Jacob Y.; Kapp, Daniel S.; Husain, Amreen; Teng, Nelson N.; Berek, Jonathan S.; Osann, Kathryn; Chan, John K. (2007). "Prognostic factors responsible for survival in sex cord stromal tumors of the ovary—An analysis of 376 women". Gynecologic Oncology. 104 (2): 396–400. doi:10.1016/j.ygyno.2006.08.032. ISSN 0090-8258.