Polycystic kidney disease differentiating polycystic kidney disease from other diseases: Difference between revisions

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Revision as of 20:00, 30 May 2018

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]

Overview

Several cystic diseases can have features of ADPKD namely autosomal recessive polycystic kidney disease (ARPKD, simple renal cysts, autosomal dominant polycystic liver disease, medullary cystic kidney disease and tuberous sclerosis complex.

Differentiating Polycystic kidney disease from other Diseases

Several cystic diseases can have a presentation similar to ADPKD especially given the variability in phenotype and severity. Below is a list of the most common cystic diseases in the differential diagnosis of autosomal dominant polycystic kidney disease:^[1]

Autosomal recessive polycystic kidney disease
Simple renal cysts
Autosomal dominant polycystic liver disease
Medullary cystic kidney disease
Tuberous sclerosis complex
Von Hippel-Lindau disease
Nephronophthisis
Joubert syndrome
Bardet-Biedel syndrome
Meckel-Gruber syndrome
Orofacial digital syndrome type 1
Glomerulocystic kidney disease

[Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as [differential dx1], [differential dx2], and [differential dx3].
[Disease name] must be differentiated from [differential dx1], [differential dx2], and [differential dx3].

As [disease name] manifests in a variety of clinical forms, differentiation must be established in accordance with the particular subtype. [Subtype name 1] must be differentiated from other diseases that cause [clinical feature 1], such as [differential dx1] and [differential dx2]. In contrast, [subtype name 2] must be differentiated from other diseases that cause [clinical feature 2], such as [differential dx3] and [differential dx4].

Preferred Table

	Symptoms			Physical examination			Lab Findings			Imaging			Histopathology
Diseases	Clinical manifestations						Para-clinical findings							Gold standard	Additional findings
	Symptoms			Physical examination			Para-clinical findings
	Symptom 1	Symptom 2	Symptom 3	Physical exam 1	Physical exam 2	Physical exam 3	Lab 1	Lab 2	Lab 3	Imaging 1	Imaging 2	Imaging 3	Histopathology
Autosomal dominant kidney disease
Autosomal recessive kidney disease
Simple renal cyst
Medullary cystic kidney disease
Tuberous sclerosis kidney disease
Von Hippel-Lindau disease

References

↑ Torres VE, Harris PC, Pirson Y (2007). "Autosomal dominant polycystic kidney disease". Lancet. 369 (9569): 1287–301. doi:10.1016/S0140-6736(07)60601-1. PMID 17434405.

Template:WH Template:WS

[pmid17434405-1] Torres VE, Harris PC, Pirson Y (2007). "Autosomal dominant polycystic kidney disease". Lancet. 369 (9569): 1287–301. doi:10.1016/S0140-6736(07)60601-1. PMID 17434405.

[1]

@@ Line 29: / Line 29: @@
 {|
 |- style="background: #4479BA; color: #FFFFFF; text-align: center;"
-! rowspan="4"  style="background: #4479BA; color: #FFFFFF; text-align: center;|Diseases
+! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diseases
-| colspan="6" rowspan="1"  style="background: #4479BA; color: #FFFFFF; text-align: center;|'''Clinical manifestations'''
+| colspan="6" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Clinical manifestations'''
-! colspan="7" rowspan="2"  style="background: #4479BA; color: #FFFFFF; text-align: center;|Para-clinical findings
+! colspan="7" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Para-clinical findings
-| colspan="1" rowspan="4"  style="background: #4479BA; color: #FFFFFF; text-align: center;|'''Gold standard'''
+| colspan="1" rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Gold standard'''
-! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;|Additional findings
+! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Additional findings
 |-
-| colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;|'''Symptoms'''
+| colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Symptoms'''
-! colspan="3" rowspan="2"  style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical examination
+! colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical examination
 |-
-! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab Findings
+! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab Findings
-! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging
+! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging
-! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;|Histopathology
+! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Histopathology
 |-
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Symptom 1
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptom 1
-! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;|Symptom 2
+! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptom 2
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Symptom 3
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptom 3
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical exam 1
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical exam 1
-! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical exam 2
+! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical exam 2
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical exam 3
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical exam 3
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab 1
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab 1
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab 2
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab 2
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab 3
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab 3
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging 1
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging 1
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging 2
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging 2
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging 3
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging 3
 |-
-| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 1
+| style="background: #DCDCDC; padding: 5px; text-align: center;" |Autosomal dominant kidney disease
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |
@@ Line 72: / Line 72: @@
 | style="background: #F5F5F5; padding: 5px;" |
 |-
-| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 2
+| style="background: #DCDCDC; padding: 5px; text-align: center;" |Autosomal recessive kidney disease
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |
@@ Line 89: / Line 89: @@
 | style="background: #F5F5F5; padding: 5px;" |
 |-
-| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 3
+| style="background: #DCDCDC; padding: 5px; text-align: center;" |Simple renal cyst
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |
@@ Line 105: / Line 105: @@
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |
-|- style="background: #4479BA; color: #FFFFFF; text-align: center;"
-!Diseases
-!Symptom 1
-! colspan="1" rowspan="1" |Symptom 2
-!Symptom 3
-!Physical exam 1
-! colspan="1" rowspan="1" |Physical exam 2
-!Physical exam 3
-!Lab 1
-!Lab 2
-!Lab 3
-!Imaging 1
-!Imaging 2
-!Imaging 3
-!Histopathology
-|'''Gold standard'''
-!Additional findings
 |-
-| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 4
+| style="background: #DCDCDC; padding: 5px; text-align: center;" |Medullary cystic kidney disease
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |
@@ Line 140: / Line 123: @@
 | style="background: #F5F5F5; padding: 5px;" |
 |-
-| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 5
+| style="background: #DCDCDC; padding: 5px; text-align: center;" |Tuberous sclerosis kidney disease
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |
@@ Line 157: / Line 140: @@
 | style="background: #F5F5F5; padding: 5px;" |
 |-
-| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 6
+| style="background: #DCDCDC; padding: 5px; text-align: center;" |Von Hippel-Lindau disease
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |