Post-streptococcal glomerulonephritis medical therapy: Difference between revisions

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==Medical therapy==
==Medical therapy==
The mainstay of treatment is pharmacotherapy, however dietary therapy is useful for controlling edema and hypertension.
The mainstay of treatment is pharmacotherapy, however dietary therapy is useful for controlling edema and hypertension
 
'''Dietary therapy'''
'''Dietary therapy'''
*Low salt intake
*Low salt intake
Line 13: Line 14:
*Water restrictions
*Water restrictions
'''Pharmacotherapy'''
'''Pharmacotherapy'''
*If  streptococcal infection is still present, it should be treated with antibiotics.<ref name="pmid11344703">{{cite journal |vauthors=Zoch-Zwierz W, Wasilewska A, Biernacka A, Tomaszewska B, Winiecka W, Wierciński R, Porowski T |title=[The course of post-streptococcal glomerulonephritis depending on methods of treatment for the preceding respiratory tract infection] |language=Polish |journal=Wiad. Lek. |volume=54 |issue=1-2 |pages=56–63 |date=2001 |pmid=11344703 |doi= |url=}}</ref>
*If  streptococcal infection is still present, it should be treated with antibiotics<ref name="pmid11344703">{{cite journal |vauthors=Zoch-Zwierz W, Wasilewska A, Biernacka A, Tomaszewska B, Winiecka W, Wierciński R, Porowski T |title=[The course of post-streptococcal glomerulonephritis depending on methods of treatment for the preceding respiratory tract infection] |language=Polish |journal=Wiad. Lek. |volume=54 |issue=1-2 |pages=56–63 |date=2001 |pmid=11344703 |doi= |url=}}</ref>
*
*To control severe hypertension, following drugs can be used:
*Pharmacologic medical therapy is recommended among patients with [disease subclass 1], [disease subclass 2], and [disease subclass 3].
**Preferred regimen: Labetalol 0.5-2 mg/kg/h IV
*Pharmacologic medical therapies for [disease name] include (either) [therapy 1], [therapy 2], and/or [therapy 3].
**If refractory to labetalol then, Preferred regimen: Diazoxide or Nitroprusside 0.5-2 mcg/kg/min IV
*Empiric therapy for [disease name] depends on [disease factor 1] and [disease factor 2].
*For mild to moderate hypertension:
*Patients with [disease subclass 1] are treated with [therapy 1], whereas patients with [disease subclass 2] are treated with [therapy 2].
**Preferred regimen: Furosemide 1-3 mg/kg PO q24h
===Disease Name===
 
* '''1 Stage 1 - Name of stage'''
** 1.1 '''Specific Organ system involved 1'''
*** 1.1.1 '''Adult'''
**** Preferred regimen (1): [[drug name]] 100 mg PO q12h for 10-21 days '''(Contraindications/specific instructions)''' 
**** Preferred regimen (2): [[drug name]] 500 mg PO q8h for 14-21 days
**** Preferred regimen (3): [[drug name]] 500 mg q12h for 14-21 days
**** Alternative regimen (1): [[drug name]] 500 mg PO q6h for 7–10 days 
**** Alternative regimen (2): [[drug name]] 500 mg PO q12h for 14–21 days
**** Alternative regimen (3): [[drug name]] 500 mg PO q6h for 14–21 days


==References==
==References==

Revision as of 18:55, 14 May 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]

Overview

Medical therapy

The mainstay of treatment is pharmacotherapy, however dietary therapy is useful for controlling edema and hypertension

Dietary therapy

  • Low salt intake
  • Low protein intake
  • Water restrictions

Pharmacotherapy

  • If streptococcal infection is still present, it should be treated with antibiotics[1]
  • To control severe hypertension, following drugs can be used:
    • Preferred regimen: Labetalol 0.5-2 mg/kg/h IV
    • If refractory to labetalol then, Preferred regimen: Diazoxide or Nitroprusside 0.5-2 mcg/kg/min IV
  • For mild to moderate hypertension:
    • Preferred regimen: Furosemide 1-3 mg/kg PO q24h

References

  1. Zoch-Zwierz W, Wasilewska A, Biernacka A, Tomaszewska B, Winiecka W, Wierciński R, Porowski T (2001). "[The course of post-streptococcal glomerulonephritis depending on methods of treatment for the preceding respiratory tract infection]". Wiad. Lek. (in Polish). 54 (1–2): 56–63. PMID 11344703.

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