Hamman-Rich syndrome medical therapy: Difference between revisions
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There is no effective treatment for acute interstitial pneumonitis, includes supportive therapy and glucocorticosteroids. | There is no effective treatment for acute interstitial pneumonitis, includes supportive therapy and glucocorticosteroids. | ||
==Supportive care== | ==Supportive care== | ||
*Patients with acute interstitial pneumonitis receive supportive care alongside the medical therapy: | *Patients with acute interstitial pneumonitis receive supportive care alongside the medical therapy<ref name="pmid16537878">{{cite journal |vauthors=Suh GY, Kang EH, Chung MP, Lee KS, Han J, Kitaichi M, Kwon OJ |title=Early intervention can improve clinical outcome of acute interstitial pneumonia |journal=Chest |volume=129 |issue=3 |pages=753–61 |date=March 2006 |pmid=16537878 |doi=10.1378/chest.129.3.753 |url=}}</ref>: | ||
**Supplemental oxygen | **Supplemental oxygen | ||
**Mechanical ventilation | **Mechanical ventilation | ||
| Line 15: | Line 15: | ||
***Sepsis | ***Sepsis | ||
*Pulmonary rehabilitation | *Pulmonary rehabilitation | ||
*Vaccination against possible causes of pulmonary inflammation as influenza and pneumococcal vaccines. | *Vaccination against possible causes of pulmonary inflammation as influenza and pneumococcal vaccines.<ref name="pmid25233284">{{cite journal |vauthors=Tomczyk S, Bennett NM, Stoecker C, Gierke R, Moore MR, Whitney CG, Hadler S, Pilishvili T |title=Use of 13-valent pneumococcal conjugate vaccine and 23-valent pneumococcal polysaccharide vaccine among adults aged ≥65 years: recommendations of the Advisory Committee on Immunization Practices (ACIP) |journal=MMWR Morb. Mortal. Wkly. Rep. |volume=63 |issue=37 |pages=822–5 |date=September 2014 |pmid=25233284 |pmc=5779453 |doi= |url=}}</ref> | ||
==Medical Therapy== | ==Medical Therapy== | ||
*Corticosteroid therapy: | *Corticosteroid therapy:<ref name="pmid19095855">{{cite journal |vauthors=Avnon LS, Pikovsky O, Sion-Vardy N, Almog Y |title=Acute interstitial pneumonia-Hamman-Rich syndrome: clinical characteristics and diagnostic and therapeutic considerations |journal=Anesth. Analg. |volume=108 |issue=1 |pages=232–7 |date=January 2009 |pmid=19095855 |doi=10.1213/ane.0b013e318188af7a |url=}}</ref> | ||
**Once the diagnosis of acute interstitial pneumonitis is confirmed, high doses of glucocorticosteroids (eg, methylprednisolone) should be administered. | **Once the diagnosis of acute interstitial pneumonitis is confirmed, high doses of glucocorticosteroids (eg, methylprednisolone) should be administered. | ||
**Monitor the patient for glucocorticosteroid-induced side effects (eg, hyperglycemia, increased susceptibility to infection, gastritis). | **Monitor the patient for glucocorticosteroid-induced side effects (eg, hyperglycemia, increased susceptibility to infection, gastritis). | ||
Revision as of 15:44, 23 March 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chandrakala Yannam, MD [2]
Overview
There is no effective treatment for acute interstitial pneumonitis, includes supportive therapy and glucocorticosteroids.
Supportive care
- Patients with acute interstitial pneumonitis receive supportive care alongside the medical therapy[1]:
- Supplemental oxygen
- Mechanical ventilation
- Prevention of complications
- Venous thromboembolism
- Gastrointestinal bleeding
- Hospital-acquired pneumonia
- Sepsis
- Pulmonary rehabilitation
- Vaccination against possible causes of pulmonary inflammation as influenza and pneumococcal vaccines.[2]
Medical Therapy
- Corticosteroid therapy:[3]
- Once the diagnosis of acute interstitial pneumonitis is confirmed, high doses of glucocorticosteroids (eg, methylprednisolone) should be administered.
- Monitor the patient for glucocorticosteroid-induced side effects (eg, hyperglycemia, increased susceptibility to infection, gastritis).
- Immunosuppressive therapy
- ↑ Suh GY, Kang EH, Chung MP, Lee KS, Han J, Kitaichi M, Kwon OJ (March 2006). "Early intervention can improve clinical outcome of acute interstitial pneumonia". Chest. 129 (3): 753–61. doi:10.1378/chest.129.3.753. PMID 16537878.
- ↑ Tomczyk S, Bennett NM, Stoecker C, Gierke R, Moore MR, Whitney CG, Hadler S, Pilishvili T (September 2014). "Use of 13-valent pneumococcal conjugate vaccine and 23-valent pneumococcal polysaccharide vaccine among adults aged ≥65 years: recommendations of the Advisory Committee on Immunization Practices (ACIP)". MMWR Morb. Mortal. Wkly. Rep. 63 (37): 822–5. PMC 5779453. PMID 25233284.
- ↑ Avnon LS, Pikovsky O, Sion-Vardy N, Almog Y (January 2009). "Acute interstitial pneumonia-Hamman-Rich syndrome: clinical characteristics and diagnostic and therapeutic considerations". Anesth. Analg. 108 (1): 232–7. doi:10.1213/ane.0b013e318188af7a. PMID 19095855.