Neonatal jaundice causes: Difference between revisions

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=== Common causes ===
=== Common causes ===
* Common causes of neonatal jaundice include the following:  
* Common causes of neonatal jaundice include the following:<ref>{{cite journal|last=Poland|first=R L|coauthors=Schultz GE, Gayatri G|title=High milk lipase activity associated with breastmilk jaundice.|journal=Pediatr Res|year=1980|volume=14|pages=1328–31}}</ref><ref>{{cite journal|last=Murphy|first=J F|coauthors=Hughes I, Verrier Jones ER, Gaskell S, Pike AW.|title=Pregnanediols and breast-milk jaundice.|journal=Arch Dis Child|year=1981|volume=56|pages=474–76}}</ref>
** Increase bilirubin production due to hemolysis. Hemolytic causes include the following:  
** Increase bilirubin production due to hemolysis. Hemolytic causes include the following:  
** Intrinsic causes of hemolysis:
** Intrinsic causes of hemolysis:
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=== Less common causes ===
=== Less common causes ===
* Less common causes of neonatal jaundice include the following disorders:  
* Less common causes of neonatal jaundice include the following disorders:<ref>{{cite journal|last=Kumral|first=A|coauthors=Ozkan H, Duman N, et al.|title=Breast milk jaundice correlates with high levels of epidermal growth factor|journal=Pediatr Res|year=2009|volume=66|pages=218–21}}</ref><ref>{{cite journal|last=Arias|first=IM|coauthors=Gartner LM, Seifter S, Furman M|title=Prolonged neonatal unconjugated hyperbilirubinemia associated with breast feeding and a steroid, pregnane-3(alpha), 20(beta)-diol in maternal milk that inhibits glucuronide formation in vitro.|journal=J Clin Invest|year=1964|volume=43|pages=2037–47}}</ref>
** Non-hemolytic causes
** Non-hemolytic causes
***[[Cephalohematoma]]
***[[Cephalohematoma]]
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* Post-hepatic
* Post-hepatic
**[[Biliary atresia]]<ref>{{cite journal|last=Kumral|first=A|coauthors=Ozkan H, Duman N, et al.|title=Breast milk jaundice correlates with high levels of epidermal growth factor|journal=Pediatr Res|year=2009|volume=66|pages=218–21}}</ref><ref>{{cite journal|last=Arias|first=IM|coauthors=Gartner LM, Seifter S, Furman M|title=Prolonged neonatal unconjugated hyperbilirubinemia associated with breast feeding and a steroid, pregnane-3(alpha), 20(beta)-diol in maternal milk that inhibits glucuronide formation in vitro.|journal=J Clin Invest|year=1964|volume=43|pages=2037–47}}</ref>
**[[Biliary atresia]]
*[[Bile duct]] obstruction<ref>{{cite journal|last=Murphy|first=J F|coauthors=Hughes I, Verrier Jones ER, Gaskell S, Pike AW.|title=Pregnanediols and breast-milk jaundice.|journal=Arch Dis Child|year=1981|volume=56|pages=474–76}}</ref><ref>{{cite journal|last=Poland|first=R L|coauthors=Schultz GE, Gayatri G|title=High milk lipase activity associated with breastmilk jaundice.|journal=Pediatr Res|year=1980|volume=14|pages=1328–31}}</ref>
*[[Bile duct]] obstruction


==References==
==References==

Revision as of 17:21, 4 February 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

Neonatal jaundice is caused by hemolysis of the RBCs mainly due to either intravascular causes or extravascular causes. Other causes include nonhemolytic causes as cephalosporines induced jaundice, genetic mutations of the UGT enzyme, and hepatic causes.

Causes

Common causes

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References

  1. Poland, R L (1980). "High milk lipase activity associated with breastmilk jaundice". Pediatr Res. 14: 1328–31. Unknown parameter |coauthors= ignored (help)
  2. Murphy, J F (1981). "Pregnanediols and breast-milk jaundice". Arch Dis Child. 56: 474–76. Unknown parameter |coauthors= ignored (help)
  3. Kumral, A (2009). "Breast milk jaundice correlates with high levels of epidermal growth factor". Pediatr Res. 66: 218–21. Unknown parameter |coauthors= ignored (help)
  4. Arias, IM (1964). "Prolonged neonatal unconjugated hyperbilirubinemia associated with breast feeding and a steroid, pregnane-3(alpha), 20(beta)-diol in maternal milk that inhibits glucuronide formation in vitro". J Clin Invest. 43: 2037–47. Unknown parameter |coauthors= ignored (help)

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