Anal fistula pathophysiology: Difference between revisions
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==Anatomy== | ==Anatomy== | ||
*The anal canal is a 2 to 4cm in length, starts at the anorectal junction to the end of anal verge. | *The anal canal is a 2 to 4cm in length, starts at the anorectal junction to the end of anal verge.<ref name="urlAnatomy and Embryology - Springer">{{cite web |url=http://link.springer.com/chapter/10.1007%2F978-1-4419-1584-9_1 |title=Anatomy and Embryology - Springer |format= |work= |accessdate=}}</ref> | ||
*It is divided into an upper and a lower part by transition zone that is seen at the dentate line or pectinate line which is surrounded by longitudinal mucosal folds, called columns of Morgagni. | *It is divided into an upper and a lower part by transition zone that is seen at the dentate line or pectinate line which is surrounded by longitudinal mucosal folds, called columns of Morgagni.<ref name="urlAnatomy and Embryology - Springer">{{cite web |url=http://link.springer.com/chapter/10.1007%2F978-1-4419-1584-9_1 |title=Anatomy and Embryology - Springer |format= |work= |accessdate=}}</ref> | ||
*Each of this fold contains anal crypts, each of which contains 3 to 12 anal glands, the distribution of these glands is not uniform with most of the glands present anterior to the position of the anal canal and fewer in the posterior position. | *Each of this fold contains anal crypts, each of which contains 3 to 12 anal glands, the distribution of these glands is not uniform with most of the glands present anterior to the position of the anal canal and fewer in the posterior position.<ref name="urlAnatomy and Embryology - Springer">{{cite web |url=http://link.springer.com/chapter/10.1007%2F978-1-4419-1584-9_1 |title=Anatomy and Embryology - Springer |format= |work= |accessdate=}}</ref> | ||
==Genetics== | ==Genetics== | ||
Revision as of 18:55, 31 January 2018
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Anal fistula Microchapters |
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Diagnosis |
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Treatment |
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Anal fistula pathophysiology On the Web |
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American Roentgen Ray Society Images of Anal fistula pathophysiology |
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Risk calculators and risk factors for Anal fistula pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]
Overview
The exact pathogenesis of [disease name] is not fully understood.
OR
It is thought that [disease name] is the result of / is mediated by / is produced by / is caused by either [hypothesis 1], [hypothesis 2], or [hypothesis 3].
OR
[Pathogen name] is usually transmitted via the [transmission route] route to the human host.
OR
Following transmission/ingestion, the [pathogen] uses the [entry site] to invade the [cell name] cell.
OR
[Disease or malignancy name] arises from [cell name]s, which are [cell type] cells that are normally involved in [function of cells].
OR
The progression to [disease name] usually involves the [molecular pathway].
OR
The pathophysiology of [disease/malignancy] depends on the histological subtype.
Pathophysiology
Anatomy
- The anal canal is a 2 to 4cm in length, starts at the anorectal junction to the end of anal verge.[1]
- It is divided into an upper and a lower part by transition zone that is seen at the dentate line or pectinate line which is surrounded by longitudinal mucosal folds, called columns of Morgagni.[1]
- Each of this fold contains anal crypts, each of which contains 3 to 12 anal glands, the distribution of these glands is not uniform with most of the glands present anterior to the position of the anal canal and fewer in the posterior position.[1]
Genetics
- [Disease name] is transmitted in [mode of genetic transmission] pattern.
- Genes involved in the pathogenesis of [disease name] include [gene1], [gene2], and [gene3].
- The development of [disease name] is the result of multiple genetic mutations.
Associated Conditions
Gross Pathology
- On gross pathology, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].
Microscopic Pathology
- On microscopic histopathological analysis, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].