STX16: Difference between revisions

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Latest revision as of 07:15, 11 September 2017

Syntaxin-16 is a protein that in humans is encoded by the STX16 gene.^[1]^[2]^[3]^[4]

It has been associated with pseudohypoparathyroidism type Ib.^[3]

Interactions

STX16 has been shown to interact with VAMP4.^[5]

References

↑ Tang BL, Low DY, Lee SS, Tan AE, Hong W (Jan 1998). "Molecular cloning and localization of human syntaxin 16, a member of the syntaxin family of SNARE proteins". Biochemical and Biophysical Research Communications. 242 (3): 673–9. doi:10.1006/bbrc.1997.8029. PMID 9464276.
↑ Simonsen A, Bremnes B, Rønning E, Aasland R, Stenmark H (Mar 1998). "Syntaxin-16, a putative Golgi t-SNARE". European Journal of Cell Biology. 75 (3): 223–31. doi:10.1016/S0171-9335(98)80116-7. PMID 9587053.
↑ ^3.0 ^3.1 Linglart A, Gensure RC, Olney RC, Jüppner H, Bastepe M (May 2005). "A novel STX16 deletion in autosomal dominant pseudohypoparathyroidism type Ib redefines the boundaries of a cis-acting imprinting control element of GNAS". American Journal of Human Genetics. 76 (5): 804–14. doi:10.1086/429932. PMC 1199370. PMID 15800843.
↑ "Entrez Gene: STX16 syntaxin 16".
↑ Mallard F, Tang BL, Galli T, Tenza D, Saint-Pol A, Yue X, Antony C, Hong W, Goud B, Johannes L (Feb 2002). "Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform". The Journal of Cell Biology. 156 (4): 653–64. doi:10.1083/jcb.200110081. PMC 2174079. PMID 11839770.

Yu Y, Zhang C, Zhou G, Wu S, Qu X, Wei H, Xing G, Dong C, Zhai Y, Wan J, Ouyang S, Li L, Zhang S, Zhou K, Zhang Y, Wu C, He F (Aug 2001). "Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs". Genome Research. 11 (8): 1392–403. doi:10.1101/gr.175501. PMC 311073. PMID 11483580.
Mallard F, Tang BL, Galli T, Tenza D, Saint-Pol A, Yue X, Antony C, Hong W, Goud B, Johannes L (Feb 2002). "Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform". The Journal of Cell Biology. 156 (4): 653–64. doi:10.1083/jcb.200110081. PMC 2174079. PMID 11839770.
Dulubova I, Yamaguchi T, Gao Y, Min SW, Huryeva I, Südhof TC, Rizo J (Jul 2002). "How Tlg2p/syntaxin 16 'snares' Vps45". The EMBO Journal. 21 (14): 3620–31. doi:10.1093/emboj/cdf381. PMC 126126. PMID 12110575.
Clark AG, Glanowski S, Nielsen R, Thomas PD, Kejariwal A, Todd MA, Tanenbaum DM, Civello D, Lu F, Murphy B, Ferriera S, Wang G, Zheng X, White TJ, Sninsky JJ, Adams MD, Cargill M (Dec 2003). "Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios". Science. 302 (5652): 1960–3. doi:10.1126/science.1088821. PMID 14671302.
Tai G, Lu L, Wang TL, Tang BL, Goud B, Johannes L, Hong W (Sep 2004). "Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network". Molecular Biology of the Cell. 15 (9): 4011–22. doi:10.1091/mbc.E03-12-0876. PMC 515336. PMID 15215310.
Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM (Jul 2004). "Functional proteomics mapping of a human signaling pathway". Genome Research. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
Amessou M, Fradagrada A, Falguières T, Lord JM, Smith DC, Roberts LM, Lamaze C, Johannes L (Apr 2007). "Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins". Journal of Cell Science. 120 (Pt 8): 1457–68. doi:10.1242/jcs.03436. PMC 1863825. PMID 17389686.

This protein-related article is a stub. You can help Wikipedia by expanding it.

[pmid9464276-1] Tang BL, Low DY, Lee SS, Tan AE, Hong W (Jan 1998). "Molecular cloning and localization of human syntaxin 16, a member of the syntaxin family of SNARE proteins". Biochemical and Biophysical Research Communications. 242 (3): 673–9. doi:10.1006/bbrc.1997.8029. PMID 9464276.

[pmid9587053-2] Simonsen A, Bremnes B, Rønning E, Aasland R, Stenmark H (Mar 1998). "Syntaxin-16, a putative Golgi t-SNARE". European Journal of Cell Biology. 75 (3): 223–31. doi:10.1016/S0171-9335(98)80116-7. PMID 9587053.

[pmid15800843-3] 3.0 ^3.1 Linglart A, Gensure RC, Olney RC, Jüppner H, Bastepe M (May 2005). "A novel STX16 deletion in autosomal dominant pseudohypoparathyroidism type Ib redefines the boundaries of a cis-acting imprinting control element of GNAS". American Journal of Human Genetics. 76 (5): 804–14. doi:10.1086/429932. PMC 1199370. PMID 15800843.

[entrez-4] "Entrez Gene: STX16 syntaxin 16".

[pmid11839770-5] Mallard F, Tang BL, Galli T, Tenza D, Saint-Pol A, Yue X, Antony C, Hong W, Goud B, Johannes L (Feb 2002). "Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform". The Journal of Cell Biology. 156 (4): 653–64. doi:10.1083/jcb.200110081. PMC 2174079. PMID 11839770.

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[2]

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[5]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''Syntaxin-16''' is a [[protein]] that in humans is encoded by the ''STX16'' [[gene]].<ref name="pmid9464276">{{cite journal | vauthors = Tang BL, Low DY, Lee SS, Tan AE, Hong W | title = Molecular cloning and localization of human syntaxin 16, a member of the syntaxin family of SNARE proteins | journal = Biochemical and Biophysical Research Communications | volume = 242 | issue = 3 | pages = 673–9 | date = Jan 1998 | pmid = 9464276 | pmc =  | doi = 10.1006/bbrc.1997.8029 }}</ref><ref name="pmid9587053">{{cite journal | vauthors = Simonsen A, Bremnes B, Rønning E, Aasland R, Stenmark H | title = Syntaxin-16, a putative Golgi t-SNARE | journal = European Journal of Cell Biology | volume = 75 | issue = 3 | pages = 223–31 | date = Mar 1998 | pmid = 9587053 | pmc =  | doi = 10.1016/S0171-9335(98)80116-7 }}</ref><ref name="pmid15800843">{{cite journal | vauthors = Linglart A, Gensure RC, Olney RC, Jüppner H, Bastepe M | title = A novel STX16 deletion in autosomal dominant pseudohypoparathyroidism type Ib redefines the boundaries of a cis-acting imprinting control element of GNAS | journal = American Journal of Human Genetics | volume = 76 | issue = 5 | pages = 804–14 | date = May 2005 | pmid = 15800843 | pmc = 1199370 | doi = 10.1086/429932 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: STX16 syntaxin 16| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8675| accessdate = }}</ref>
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+It has been associated with [[pseudohypoparathyroidism]] type Ib.<ref name="pmid15800843" />
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Syntaxin 16
- | HGNCid = 11431
- | Symbol = STX16
- | AltSymbols =; MGC90328; SYN16; hsyn16
- | OMIM = 603666
- | ECnumber =
- | Homologene = 2791
- | MGIid = 1923396
- | Function = {{GNF_GO|id=GO:0005486 |text = SNAP receptor activity}} {{GNF_GO|id=GO:0008565 |text = protein transporter activity}}
- | Component = {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0005792 |text = microsome}} {{GNF_GO|id=GO:0005794 |text = Golgi apparatus}} {{GNF_GO|id=GO:0005795 |text = Golgi stack}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
- | Process = {{GNF_GO|id=GO:0006886 |text = intracellular protein transport}} {{GNF_GO|id=GO:0006891 |text = intra-Golgi vesicle-mediated transport}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 8675
-    | Hs_Ensembl =
-    | Hs_RefseqProtein = NP_001001433
-    | Hs_RefseqmRNA = NM_001001433
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr =
-    | Hs_GenLoc_start =
-    | Hs_GenLoc_end =
-    | Hs_Uniprot =
-    | Mm_EntrezGene = 228960
-    | Mm_Ensembl = ENSMUSG00000027522
-    | Mm_RefseqmRNA = NM_172675
-    | Mm_RefseqProtein = NP_766263
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 2
-    | Mm_GenLoc_start = 173719260
-    | Mm_GenLoc_end = 173742595
-    | Mm_Uniprot = Q8C0W8
-  }}
-}}
-'''Syntaxin 16''', also known as '''STX16''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: STX16 syntaxin 16| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8675| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+== Interactions ==
-{{PBB_Summary
-| section_title =
-| summary_text =
-}}
-==References==
+STX16 has been shown to [[Protein-protein interaction|interact]] with [[VAMP4]].<ref name=pmid11839770>{{cite journal | vauthors = Mallard F, Tang BL, Galli T, Tenza D, Saint-Pol A, Yue X, Antony C, Hong W, Goud B, Johannes L | title = Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform | journal = The Journal of Cell Biology | volume = 156 | issue = 4 | pages = 653–64 | date = Feb 2002 | pmid = 11839770 | pmc = 2174079 | doi = 10.1083/jcb.200110081 }}</ref>
-{{reflist|2}}
-==Further reading==
+== References ==
+{{reflist}}
+== Further reading ==
 {{refbegin | 2}}
-{{PBB_Further_reading
+* {{cite journal | vauthors = Yu Y, Zhang C, Zhou G, Wu S, Qu X, Wei H, Xing G, Dong C, Zhai Y, Wan J, Ouyang S, Li L, Zhang S, Zhou K, Zhang Y, Wu C, He F | title = Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs | journal = Genome Research | volume = 11 | issue = 8 | pages = 1392–403 | date = Aug 2001 | pmid = 11483580 | pmc = 311073 | doi = 10.1101/gr.175501 }}
-| citations =
+* {{cite journal | vauthors = Mallard F, Tang BL, Galli T, Tenza D, Saint-Pol A, Yue X, Antony C, Hong W, Goud B, Johannes L | title = Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform | journal = The Journal of Cell Biology | volume = 156 | issue = 4 | pages = 653–64 | date = Feb 2002 | pmid = 11839770 | pmc = 2174079 | doi = 10.1083/jcb.200110081 }}
-*{{cite journal  | author=Tang BL, Low DY, Lee SS, ''et al.'' |title=Molecular cloning and localization of human syntaxin 16, a member of the syntaxin family of SNARE proteins. |journal=Biochem. Biophys. Res. Commun. |volume=242 |issue= 3 |pages= 673-9 |year= 1998 |pmid= 9464276 |doi= 10.1006/bbrc.1997.8029 }}
+* {{cite journal | vauthors = Dulubova I, Yamaguchi T, Gao Y, Min SW, Huryeva I, Südhof TC, Rizo J | title = How Tlg2p/syntaxin 16 'snares' Vps45 | journal = The EMBO Journal | volume = 21 | issue = 14 | pages = 3620–31 | date = Jul 2002 | pmid = 12110575 | pmc = 126126 | doi = 10.1093/emboj/cdf381 }}
-*{{cite journal  | author=Simonsen A, Bremnes B, Rønning E, ''et al.'' |title=Syntaxin-16, a putative Golgi t-SNARE. |journal=Eur. J. Cell Biol. |volume=75 |issue= 3 |pages= 223-31 |year= 1998 |pmid= 9587053 |doi=  }}
+* {{cite journal | vauthors = Clark AG, Glanowski S, Nielsen R, Thomas PD, Kejariwal A, Todd MA, Tanenbaum DM, Civello D, Lu F, Murphy B, Ferriera S, Wang G, Zheng X, White TJ, Sninsky JJ, Adams MD, Cargill M | title = Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios | journal = Science | volume = 302 | issue = 5652 | pages = 1960–3 | date = Dec 2003 | pmid = 14671302 | doi = 10.1126/science.1088821 }}
-*{{cite journal  | author=Yu Y, Zhang C, Zhou G, ''et al.'' |title=Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs. |journal=Genome Res. |volume=11 |issue= 8 |pages= 1392-403 |year= 2001 |pmid= 11483580 |doi= 10.1101/gr.175501 }}
+* {{cite journal | vauthors = Tai G, Lu L, Wang TL, Tang BL, Goud B, Johannes L, Hong W | title = Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network | journal = Molecular Biology of the Cell | volume = 15 | issue = 9 | pages = 4011–22 | date = Sep 2004 | pmid = 15215310 | pmc = 515336 | doi = 10.1091/mbc.E03-12-0876 }}
-*{{cite journal  | author=Deloukas P, Matthews LH, Ashurst J, ''et al.'' |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865-71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a }}
+* {{cite journal | vauthors = Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM | title = Functional proteomics mapping of a human signaling pathway | journal = Genome Research | volume = 14 | issue = 7 | pages = 1324–32 | date = Jul 2004 | pmid = 15231748 | pmc = 442148 | doi = 10.1101/gr.2334104 }}
-*{{cite journal  | author=Mallard F, Tang BL, Galli T, ''et al.'' |title=Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform. |journal=J. Cell Biol. |volume=156 |issue= 4 |pages= 653-64 |year= 2002 |pmid= 11839770 |doi= 10.1083/jcb.200110081 }}
+* {{cite journal | vauthors = Amessou M, Fradagrada A, Falguières T, Lord JM, Smith DC, Roberts LM, Lamaze C, Johannes L | title = Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins | journal = Journal of Cell Science | volume = 120 | issue = Pt 8 | pages = 1457–68 | date = Apr 2007 | pmid = 17389686 | pmc = 1863825 | doi = 10.1242/jcs.03436 }}
-*{{cite journal  | author=Dulubova I, Yamaguchi T, Gao Y, ''et al.'' |title=How Tlg2p/syntaxin 16 'snares' Vps45. |journal=EMBO J. |volume=21 |issue= 14 |pages= 3620-31 |year= 2002 |pmid= 12110575 |doi= 10.1093/emboj/cdf381 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
-*{{cite journal  | author=Clark AG, Glanowski S, Nielsen R, ''et al.'' |title=Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios. |journal=Science |volume=302 |issue= 5652 |pages= 1960-3 |year= 2003 |pmid= 14671302 |doi= 10.1126/science.1088821 }}
-*{{cite journal  | author=Tai G, Lu L, Wang TL, ''et al.'' |title=Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network. |journal=Mol. Biol. Cell |volume=15 |issue= 9 |pages= 4011-22 |year= 2005 |pmid= 15215310 |doi= 10.1091/mbc.E03-12-0876 }}
-*{{cite journal  | author=Colland F, Jacq X, Trouplin V, ''et al.'' |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324-32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
-*{{cite journal  | author=Linglart A, Gensure RC, Olney RC, ''et al.'' |title=A novel STX16 deletion in autosomal dominant pseudohypoparathyroidism type Ib redefines the boundaries of a cis-acting imprinting control element of GNAS. |journal=Am. J. Hum. Genet. |volume=76 |issue= 5 |pages= 804-14 |year= 2005 |pmid= 15800843 |doi= 10.1086/429932 }}
-*{{cite journal  | author=Amessou M, Fradagrada A, Falguières T, ''et al.'' |title=Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins. |journal=J. Cell. Sci. |volume=120 |issue= Pt 8 |pages= 1457-68 |year= 2007 |pmid= 17389686 |doi= 10.1242/jcs.03436 }}
-}}
 {{refend}}
+{{Vesicular transport proteins}}
 {{protein-stub}}
-{{WikiDoc Sources}}

STX16: Difference between revisions

Latest revision as of 07:15, 11 September 2017

Interactions

References

Further reading

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