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{{Infobox_gene}}
{{PBB_Controls
'''14-3-3 protein beta/alpha''' is a [[protein]] that in humans is encoded by the ''YWHAB'' [[gene]].<ref name="pmid8617504">{{cite journal | vauthors = Tommerup N, Leffers H | title = Assignment of the human genes encoding 14,3-3 Eta (YWHAH) to 22q12, 14-3-3 zeta (YWHAZ) to 2p25.1-p25.2, and 14-3-3 beta (YWHAB) to 20q13.1 by in situ hybridization | journal = Genomics | volume = 33 | issue = 1 | pages = 149–50 | date = June 1996 | pmid = 8617504 | pmc = | doi = 10.1006/geno.1996.0176 }}</ref>
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
 
| image = PBB_Protein_YWHAB_image.jpg
This gene encodes a protein belonging to the [[14-3-3]] family of proteins, members of which mediate signal transduction by binding to [[phosphoserine]]-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with [[RAF1]] and [[Cdc25|CDC25]] [[phosphatase]]s, suggesting that it may play a role in linking [[mitogenic]] signaling and the [[cell cycle]] machinery. Two transcript variants, which encode the same protein, have been identified for this gene.<ref>{{cite web | title = Entrez Gene: YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7529| accessdate = }}</ref>
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 2bq0.
 
  | PDB = {{PDB2|2bq0}}, {{PDB2|2c23}}
==Interactions==
| Name = Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
YWHAB has been shown to [[Protein-protein interaction|interact]] with:
  | HGNCid = 12849
{{div col|colwidth=20em}}
  | Symbol = YWHAB
* [[BRAF (gene)|BRAF]],<ref name = pmid17353931>{{cite journal | vauthors = Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D | title = Large-scale mapping of human protein-protein interactions by mass spectrometry | journal = Mol. Syst. Biol. | volume = 3 | issue = | pages = 89 | pmid = 17353931 | pmc = 1847948 | doi = 10.1038/msb4100134 | year=2007}}</ref><ref name = pmid10931830>{{cite journal | vauthors = Qiu W, Zhuang S, von Lintig FC, Boss GR, Pilz RB | title = Cell type-specific regulation of B-Raf kinase by cAMP and 14-3-3 proteins | journal = J. Biol. Chem. | volume = 275 | issue = 41 | pages = 31921–9 | date = October 2000 | pmid = 10931830 | doi = 10.1074/jbc.M003327200 }}</ref>
  | AltSymbols =; HS1; GW128; KCIP-1
* [[C-Raf]],<ref name = pmid7644510/><ref name = pmid12620389>{{cite journal | vauthors = Yuryev A, Wennogle LP | title = Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid analysis | journal = Genomics | volume = 81 | issue = 2 | pages = 112–25 | date = February 2003 | pmid = 12620389 | doi =  10.1016/S0888-7543(02)00008-3}}</ref><ref name = pmid12360521>{{cite journal | vauthors = Truong AB, Masters SC, Yang H, Fu H | title = Role of the 14-3-3 C-terminal loop in ligand interaction | journal = Proteins | volume = 49 | issue = 3 | pages = 321–5 | date = November 2002 | pmid = 12360521 | doi = 10.1002/prot.10210 }}</ref><ref name = pmid10620507>{{cite journal | vauthors = Van Der Hoeven PC, Van Der Wal JC, Ruurs P, Van Dijk MC, Van Blitterswijk J | title = 14-3-3 isotypes facilitate coupling of protein kinase C-zeta to Raf-1: negative regulation by 14-3-3 phosphorylation | journal = Biochem. J. | volume = 345 | issue = 2| pages = 297–306 | date = January 2000 | pmid = 10620507 | pmc = 1220759 | doi =  10.1042/0264-6021:3450297}}</ref><ref name = pmid10848612>{{cite journal | vauthors = Yuryev A, Ono M, Goff SA, Macaluso F, Wennogle LP | title = Isoform-specific localization of A-RAF in mitochondria | journal = Mol. Cell. Biol. | volume = 20 | issue = 13 | pages = 4870–8 | date = July 2000 | pmid = 10848612 | pmc = 85938 | doi =  10.1128/MCB.20.13.4870-4878.2000}}</ref><ref name = pmid8702721>{{cite journal | vauthors = Vincenz C, Dixit VM | title = 14-3-3 proteins associate with A20 in an isoform-specific manner and function both as chaperone and adapter molecules | journal = J. Biol. Chem. | volume = 271 | issue = 33 | pages = 20029–34 | date = August 1996 | pmid = 8702721 | doi =  10.1074/jbc.271.33.20029}}</ref>
| OMIM = 601289
* [[CD29]],<ref name = pmid11313964>{{cite journal | vauthors = Han DC, Rodriguez LG, Guan JL | title = Identification of a novel interaction between integrin beta1 and 14-3-3beta | journal = Oncogene | volume = 20 | issue = 3 | pages = 346–57 | date = January 2001 | pmid = 11313964 | doi = 10.1038/sj.onc.1204068 }}</ref>
| ECnumber =   
* [[CDC25A]],<ref name = pmid7644510>{{cite journal | vauthors = Conklin DS, Galaktionov K, Beach D | title = 14-3-3 proteins associate with cdc25 phosphatases | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 92 | issue = 17 | pages = 7892–6 | date = August 1995 | pmid = 7644510 | pmc = 41252 | doi = 10.1073/pnas.92.17.7892}}</ref>
| Homologene = 20724
* [[CDC25B]],<ref name = pmid7644510/><ref name = pmid10713667>{{cite journal | vauthors = Mils V, Baldin V, Goubin F, Pinta I, Papin C, Waye M, Eychene A, Ducommun B | title = Specific interaction between 14-3-3 isoforms and the human CDC25B phosphatase | journal = Oncogene | volume = 19 | issue = 10 | pages = 1257–65 | date = March 2000 | pmid = 10713667 | doi = 10.1038/sj.onc.1203419 }}</ref>
| MGIid = 1891917
* [[Cbl gene]],<ref name = pmid9367879>{{cite journal | vauthors = Robertson H, Langdon WY, Thien CB, Bowtell DD | title = A c-Cbl yeast two hybrid screen reveals interactions with 14-3-3 isoforms and cytoskeletal components | journal = Biochem. Biophys. Res. Commun. | volume = 240 | issue = 1 | pages = 46–50 | date = November 1997 | pmid = 9367879 | doi = 10.1006/bbrc.1997.7608 }}</ref>
| GeneAtlas_image1 = PBB_GE_YWHAB_208743_s_at_tn.png
* [[EPB41L3]],<ref name = pmid17353931/><ref name = pmid11996670>{{cite journal | vauthors = Yu T, Robb VA, Singh V, Gutmann DH, Newsham IF | title = The 4.1/ezrin/radixin/moesin domain of the DAL-1/Protein 4.1B tumour suppressor interacts with 14-3-3 proteins | journal = Biochem. J. | volume = 365 | issue = Pt 3 | pages = 783–9 | date = August 2002 | pmid = 11996670 | pmc = 1222735 | doi = 10.1042/BJ20020060 }}</ref>
| GeneAtlas_image2 = PBB_GE_YWHAB_217717_s_at_tn.png
* [[HDAC4]]<ref name = pmid10869435>{{cite journal | vauthors = Grozinger CM, Schreiber SL | title = Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 97 | issue = 14 | pages = 7835–40 | date = July 2000 | pmid = 10869435 | pmc = 16631 | doi = 10.1073/pnas.140199597 }}</ref>
| GeneAtlas_image3 = PBB_GE_YWHAB_217718_s_at_tn.png
* [[KCNK3]],<ref name = pmid12437930>{{cite journal | vauthors = O'Kelly I, Butler MH, Zilberberg N, Goldstein SA | title = Forward transport. 14-3-3 binding overcomes retention in endoplasmic reticulum by dibasic signals | journal = Cell | volume = 111 | issue = 4 | pages = 577–88 | date = November 2002 | pmid = 12437930 | doi = 10.1016/S0092-8674(02)01040-1}}</ref>
| Function = {{GNF_GO|id=GO:0004497 |text = monooxygenase activity}} {{GNF_GO|id=GO:0019904 |text = protein domain specific binding}}  
* [[MAPK7]],<ref name = pmid14679215>{{cite journal | vauthors = Zheng Q, Yin G, Yan C, Cavet M, Berk BC | title = 14-3-3beta binds to big mitogen-activated protein kinase 1 (BMK1/ERK5) and regulates BMK1 function | journal = J. Biol. Chem. | volume = 279 | issue = 10 | pages = 8787–91 | date = March 2004 | pmid = 14679215 | doi = 10.1074/jbc.M310212200 }}</ref>
| Component = {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0048471 |text = perinuclear region of cytoplasm}}  
* [[PTPN3]],<ref name = pmid9341175>{{cite journal | vauthors = Zhang SH, Kobayashi R, Graves PR, Piwnica-Worms H, Tonks NK | title = Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3beta protein | journal = J. Biol. Chem. | volume = 272 | issue = 43 | pages = 27281–7 | date = October 1997 | pmid = 9341175 | doi = 10.1074/jbc.272.43.27281}}</ref>
| Process = {{GNF_GO|id=GO:0006605 |text = protein targeting}}  
* [[Protein kinase Mζ|PRKCZ]],<ref name = pmid10620507/>
| Orthologs = {{GNF_Ortholog_box
* [[RPS6KA1]],<ref name = pmid12618428>{{cite journal | vauthors = Cavet ME, Lehoux S, Berk BC | title = 14-3-3beta is a p90 ribosomal S6 kinase (RSK) isoform 1-binding protein that negatively regulates RSK kinase activity | journal = J. Biol. Chem. | volume = 278 | issue = 20 | pages = 18376–83 | date = May 2003 | pmid = 12618428 | doi = 10.1074/jbc.M208475200 }}</ref>
    | Hs_EntrezGene = 7529
* [[TESK1]],<ref name = pmid11555644>{{cite journal | vauthors = Toshima JY, Toshima J, Watanabe T, Mizuno K | title = Binding of 14-3-3beta regulates the kinase activity and subcellular localization of testicular protein kinase 1 | journal = J. Biol. Chem. | volume = 276 | issue = 46 | pages = 43471–81 | date = November 2001 | pmid = 11555644 | doi = 10.1074/jbc.M104620200 }}</ref>
    | Hs_Ensembl = ENSG00000166913
* [[TNFAIP3]],<ref name = pmid8702721/>  and
    | Hs_RefseqProtein = NP_003395
* [[Wee1-like protein kinase|WEE1]].<ref name = pmid10775038>{{cite journal | vauthors = Wang Y, Jacobs C, Hook KE, Duan H, Booher RN, Sun Y | title = Binding of 14-3-3beta to the carboxyl terminus of Wee1 increases Wee1 stability, kinase activity, and G2-M cell population | journal = Cell Growth Differ. | volume = 11 | issue = 4 | pages = 211–9 | date = April 2000 | pmid = 10775038 | doi =  }}</ref>
    | Hs_RefseqmRNA = NM_003404
{{Div col end}}
    | Hs_GenLoc_db =
    | Hs_GenLoc_chr = 20
    | Hs_GenLoc_start = 42947731
    | Hs_GenLoc_end = 42970587
    | Hs_Uniprot = P31946
    | Mm_EntrezGene = 54401
    | Mm_Ensembl = ENSMUSG00000018326
    | Mm_RefseqmRNA = NM_018753
    | Mm_RefseqProtein = NP_061223
    | Mm_GenLoc_db =
    | Mm_GenLoc_chr = 2
    | Mm_GenLoc_start = 163686638
    | Mm_GenLoc_end = 163710028
    | Mm_Uniprot = Q9CQV8
  }}
}}
'''Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide''', also known as '''YWHAB''', is a human [[gene]].


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.<ref>{{cite web | title = Entrez Gene: YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7529| accessdate = }}</ref>
}}
==See also==
==See also==
*[[14-3-3 protein]]s
*[[14-3-3 protein]]s


==References==
==References==
{{reflist|2}}
{{Reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{Refbegin | 2}}
{{PBB_Further_reading
*{{cite journal | vauthors = Kino T, Pavlakis GN | title = Partner molecules of accessory protein Vpr of the human immunodeficiency virus type 1 | journal = DNA Cell Biol. | volume = 23 | issue = 4 | pages = 193–205 | year = 2004 | pmid = 15142377 | doi = 10.1089/104454904773819789 }}
| citations =
*{{cite journal | vauthors = Kino T, Chrousos GP | title = Human immunodeficiency virus type-1 accessory protein Vpr: a causative agent of the AIDS-related insulin resistance/lipodystrophy syndrome? | journal = Ann. N. Y. Acad. Sci. | volume = 1024 | issue =  | pages = 153–67 | year = 2004 | pmid = 15265780 | doi = 10.1196/annals.1321.013 }}
*{{cite journal | author=Kino T, Pavlakis GN |title=Partner molecules of accessory protein Vpr of the human immunodeficiency virus type 1. |journal=DNA Cell Biol. |volume=23 |issue= 4 |pages= 193-205 |year= 2004 |pmid= 15142377 |doi= 10.1089/104454904773819789 }}
*{{cite journal | vauthors = Calinisan V, Gravem D, Chen RP, Brittin S, Mohandas N, Lecomte MC, Gascard P | title = New insights into potential functions for the protein 4.1 superfamily of proteins in kidney epithelium | journal = Front. Biosci. | volume = 11 | issue =  | pages = 1646–66 | year = 2006 | pmid = 16368544 | doi = 10.2741/1911 }}
*{{cite journal | author=Kino T, Chrousos GP |title=Human immunodeficiency virus type-1 accessory protein Vpr: a causative agent of the AIDS-related insulin resistance/lipodystrophy syndrome? |journal=Ann. N. Y. Acad. Sci. |volume=1024 |issue=  |pages= 153-67 |year= 2004 |pmid= 15265780 |doi= 10.1196/annals.1321.013 }}
{{Refend}}
*{{cite journal | author=Calinisan V, Gravem D, Chen RP, ''et al.'' |title=New insights into potential functions for the protein 4.1 superfamily of proteins in kidney epithelium. |journal=Front. Biosci. |volume=11 |issue=  |pages= 1646-66 |year= 2006 |pmid= 16368544 |doi= }}
 
}}
{{PDB Gallery|geneid=7529}}
{{refend}}


{{protein-stub}}
[[Category:14-3-3 proteins]]
{{WikiDoc Sources}}

Latest revision as of 21:49, 4 October 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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n/a

Ensembl

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UniProt

n/a

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RefSeq (mRNA)

n/a

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

14-3-3 protein beta/alpha is a protein that in humans is encoded by the YWHAB gene.[1]

Function

This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.[2]

Interactions

YWHAB has been shown to interact with:

See also

References

  1. ↑ Tommerup N, Leffers H (June 1996). "Assignment of the human genes encoding 14,3-3 Eta (YWHAH) to 22q12, 14-3-3 zeta (YWHAZ) to 2p25.1-p25.2, and 14-3-3 beta (YWHAB) to 20q13.1 by in situ hybridization". Genomics. 33 (1): 149–50. doi:10.1006/geno.1996.0176. PMID 8617504.
  2. ↑ "Entrez Gene: YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide".
  3. ↑ 3.0 3.1 Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
  4. ↑ Qiu W, Zhuang S, von Lintig FC, Boss GR, Pilz RB (October 2000). "Cell type-specific regulation of B-Raf kinase by cAMP and 14-3-3 proteins". J. Biol. Chem. 275 (41): 31921–9. doi:10.1074/jbc.M003327200. PMID 10931830.
  5. ↑ 5.0 5.1 5.2 Conklin DS, Galaktionov K, Beach D (August 1995). "14-3-3 proteins associate with cdc25 phosphatases". Proc. Natl. Acad. Sci. U.S.A. 92 (17): 7892–6. doi:10.1073/pnas.92.17.7892. PMC 41252. PMID 7644510.
  6. ↑ Yuryev A, Wennogle LP (February 2003). "Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid analysis". Genomics. 81 (2): 112–25. doi:10.1016/S0888-7543(02)00008-3. PMID 12620389.
  7. ↑ Truong AB, Masters SC, Yang H, Fu H (November 2002). "Role of the 14-3-3 C-terminal loop in ligand interaction". Proteins. 49 (3): 321–5. doi:10.1002/prot.10210. PMID 12360521.
  8. ↑ 8.0 8.1 Van Der Hoeven PC, Van Der Wal JC, Ruurs P, Van Dijk MC, Van Blitterswijk J (January 2000). "14-3-3 isotypes facilitate coupling of protein kinase C-zeta to Raf-1: negative regulation by 14-3-3 phosphorylation". Biochem. J. 345 (2): 297–306. doi:10.1042/0264-6021:3450297. PMC 1220759. PMID 10620507.
  9. ↑ Yuryev A, Ono M, Goff SA, Macaluso F, Wennogle LP (July 2000). "Isoform-specific localization of A-RAF in mitochondria". Mol. Cell. Biol. 20 (13): 4870–8. doi:10.1128/MCB.20.13.4870-4878.2000. PMC 85938. PMID 10848612.
  10. ↑ 10.0 10.1 Vincenz C, Dixit VM (August 1996). "14-3-3 proteins associate with A20 in an isoform-specific manner and function both as chaperone and adapter molecules". J. Biol. Chem. 271 (33): 20029–34. doi:10.1074/jbc.271.33.20029. PMID 8702721.
  11. ↑ Han DC, Rodriguez LG, Guan JL (January 2001). "Identification of a novel interaction between integrin beta1 and 14-3-3beta". Oncogene. 20 (3): 346–57. doi:10.1038/sj.onc.1204068. PMID 11313964.
  12. ↑ Mils V, Baldin V, Goubin F, Pinta I, Papin C, Waye M, Eychene A, Ducommun B (March 2000). "Specific interaction between 14-3-3 isoforms and the human CDC25B phosphatase". Oncogene. 19 (10): 1257–65. doi:10.1038/sj.onc.1203419. PMID 10713667.
  13. ↑ Robertson H, Langdon WY, Thien CB, Bowtell DD (November 1997). "A c-Cbl yeast two hybrid screen reveals interactions with 14-3-3 isoforms and cytoskeletal components". Biochem. Biophys. Res. Commun. 240 (1): 46–50. doi:10.1006/bbrc.1997.7608. PMID 9367879.
  14. ↑ Yu T, Robb VA, Singh V, Gutmann DH, Newsham IF (August 2002). "The 4.1/ezrin/radixin/moesin domain of the DAL-1/Protein 4.1B tumour suppressor interacts with 14-3-3 proteins". Biochem. J. 365 (Pt 3): 783–9. doi:10.1042/BJ20020060. PMC 1222735. PMID 11996670.
  15. ↑ Grozinger CM, Schreiber SL (July 2000). "Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization". Proc. Natl. Acad. Sci. U.S.A. 97 (14): 7835–40. doi:10.1073/pnas.140199597. PMC 16631. PMID 10869435.
  16. ↑ O'Kelly I, Butler MH, Zilberberg N, Goldstein SA (November 2002). "Forward transport. 14-3-3 binding overcomes retention in endoplasmic reticulum by dibasic signals". Cell. 111 (4): 577–88. doi:10.1016/S0092-8674(02)01040-1. PMID 12437930.
  17. ↑ Zheng Q, Yin G, Yan C, Cavet M, Berk BC (March 2004). "14-3-3beta binds to big mitogen-activated protein kinase 1 (BMK1/ERK5) and regulates BMK1 function". J. Biol. Chem. 279 (10): 8787–91. doi:10.1074/jbc.M310212200. PMID 14679215.
  18. ↑ Zhang SH, Kobayashi R, Graves PR, Piwnica-Worms H, Tonks NK (October 1997). "Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3beta protein". J. Biol. Chem. 272 (43): 27281–7. doi:10.1074/jbc.272.43.27281. PMID 9341175.
  19. ↑ Cavet ME, Lehoux S, Berk BC (May 2003). "14-3-3beta is a p90 ribosomal S6 kinase (RSK) isoform 1-binding protein that negatively regulates RSK kinase activity". J. Biol. Chem. 278 (20): 18376–83. doi:10.1074/jbc.M208475200. PMID 12618428.
  20. ↑ Toshima JY, Toshima J, Watanabe T, Mizuno K (November 2001). "Binding of 14-3-3beta regulates the kinase activity and subcellular localization of testicular protein kinase 1". J. Biol. Chem. 276 (46): 43471–81. doi:10.1074/jbc.M104620200. PMID 11555644.
  21. ↑ Wang Y, Jacobs C, Hook KE, Duan H, Booher RN, Sun Y (April 2000). "Binding of 14-3-3beta to the carboxyl terminus of Wee1 increases Wee1 stability, kinase activity, and G2-M cell population". Cell Growth Differ. 11 (4): 211–9. PMID 10775038.

Further reading

  • Kino T, Pavlakis GN (2004). "Partner molecules of accessory protein Vpr of the human immunodeficiency virus type 1". DNA Cell Biol. 23 (4): 193–205. doi:10.1089/104454904773819789. PMID 15142377.
  • Kino T, Chrousos GP (2004). "Human immunodeficiency virus type-1 accessory protein Vpr: a causative agent of the AIDS-related insulin resistance/lipodystrophy syndrome?". Ann. N. Y. Acad. Sci. 1024: 153–67. doi:10.1196/annals.1321.013. PMID 15265780.
  • Calinisan V, Gravem D, Chen RP, Brittin S, Mohandas N, Lecomte MC, Gascard P (2006). "New insights into potential functions for the protein 4.1 superfamily of proteins in kidney epithelium". Front. Biosci. 11: 1646–66. doi:10.2741/1911. PMID 16368544.
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