POU3F1: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
m (Robot: Automated text replacement (-{{reflist}} +{{reflist|2}}, -<references /> +{{reflist|2}}, -{{WikiDoc Cardiology Network Infobox}} +))
 
(10.1093/oxfordjournals.humrep.a135792)
Line 1: Line 1:
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''POU domain, class 3, transcription factor 1''' (also known as '''Oct-6''') is a [[protein]] that in humans is encoded by the ''POU3F1'' [[gene]].<ref name="pmid8451175">{{cite journal | vauthors = Tobler A, Schreiber E, Fontana A | title = The human Oct-6 POU transcription factor lacks the first 50 amino acids of its murine counterpart | journal = Nucleic Acids Research | volume = 21 | issue = 4 | pages = 1043 | date = Feb 1993 | pmid = 8451175 | pmc = 309249 | doi = 10.1093/nar/21.4.1043 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: POU3F1 POU domain, class 3, transcription factor 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5453| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== See also ==
{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = POU domain, class 3, transcription factor 1
| HGNCid = 9214
| Symbol = POU3F1
| AltSymbols =; OCT6; OTF6; SCIP
| OMIM = 602479
| ECnumber = 
| Homologene = 20590
| MGIid = 101896
| GeneAtlas_image1 = PBB_GE_POU3F1_208345_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_POU3F1_210475_at_tn.png
| Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}} {{GNF_GO|id=GO:0043565 |text = sequence-specific DNA binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0008366 |text = axon ensheathment}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 5453
    | Hs_Ensembl = ENSG00000185668
    | Hs_RefseqProtein = NP_002690
    | Hs_RefseqmRNA = NM_002699
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 38282086
    | Hs_GenLoc_end = 38285053
    | Hs_Uniprot = Q03052
    | Mm_EntrezGene = 18991
    | Mm_Ensembl = 
    | Mm_RefseqmRNA = XM_980403
    | Mm_RefseqProtein = XP_985497
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 
    | Mm_GenLoc_start = 
    | Mm_GenLoc_end = 
    | Mm_Uniprot = 
  }}
}}
'''POU domain, class 3, transcription factor 1''', also known as '''POU3F1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: POU3F1 POU domain, class 3, transcription factor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5453| accessdate = }}</ref>
 
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text =
}}
 
==See also==
* [[Octamer transcription factor]]
* [[Octamer transcription factor]]


==References==
== References ==
{{reflist|2}}
{{reflist}}


==Further reading==
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Monuki ES, Kuhn R, Weinmaster G, Trapp BD, Lemke G | title = Expression and activity of the POU transcription factor SCIP | journal = Science | volume = 249 | issue = 4974 | pages = 1300–3 | date = Sep 1990 | pmid = 1975954 | doi = 10.1126/science.1975954 }}
| citations =
* {{cite journal | vauthors = Suzuki N, Rohdewohld H, Neuman T, Gruss P, Schöler HR | title = Oct-6: a POU transcription factor expressed in embryonal stem cells and in the developing brain | journal = The EMBO Journal | volume = 9 | issue = 11 | pages = 3723–32 | date = Nov 1990 | pmid = 1976514 | pmc = 552128 | doi =  }}
*{{cite journal | author=Monuki ES, Kuhn R, Weinmaster G, ''et al.'' |title=Expression and activity of the POU transcription factor SCIP. |journal=Science |volume=249 |issue= 4974 |pages= 1300-3 |year= 1990 |pmid= 1975954 |doi= }}
* {{cite journal | vauthors = Zwilling S, König H, Wirth T | title = High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors | journal = The EMBO Journal | volume = 14 | issue = 6 | pages = 1198–208 | date = Mar 1995 | pmid = 7720710 | pmc = 398197 | doi =  }}
*{{cite journal | author=Suzuki N, Rohdewohld H, Neuman T, ''et al.'' |title=Oct-6: a POU transcription factor expressed in embryonal stem cells and in the developing brain. |journal=EMBO J. |volume=9 |issue= 11 |pages= 3723-32 |year= 1990 |pmid= 1976514 |doi=  }}
* {{cite journal | vauthors = Leger H, Sock E, Renner K, Grummt F, Wegner M | title = Functional interaction between the POU domain protein Tst-1/Oct-6 and the high-mobility-group protein HMG-I/Y | journal = Molecular and Cellular Biology | volume = 15 | issue = 7 | pages = 3738–47 | date = Jul 1995 | pmid = 7791781 | pmc = 230612 | doi =  10.1128/mcb.15.7.3738}}
*{{cite journal | author=Zwilling S, König H, Wirth T |title=High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors. |journal=EMBO J. |volume=14 |issue= 6 |pages= 1198-208 |year= 1995 |pmid= 7720710 |doi=  }}
* {{cite journal | vauthors = Faus I, Hsu HJ, Fuchs E | title = Oct-6: a regulator of keratinocyte gene expression in stratified squamous epithelia | journal = Molecular and Cellular Biology | volume = 14 | issue = 5 | pages = 3263–75 | date = May 1994 | pmid = 7909356 | pmc = 358693 | doi =  10.1128/mcb.14.5.3263}}
*{{cite journal | author=Leger H, Sock E, Renner K, ''et al.'' |title=Functional interaction between the POU domain protein Tst-1/Oct-6 and the high-mobility-group protein HMG-I/Y. |journal=Mol. Cell. Biol. |volume=15 |issue= 7 |pages= 3738-47 |year= 1995 |pmid= 7791781 |doi=  }}
* {{cite journal | vauthors = Abdel-Rahman B, Fiddler M, Rappolee D, Pergament E | title = Expression of transcription regulating genes in human preimplantation embryos | journal = Human Reproduction | volume = 10 | issue = 10 | pages = 2787–92 | date = Oct 1995 | pmid = 8567814 | doi = 10.1093/oxfordjournals.humrep.a135792 }}
*{{cite journal | author=Faus I, Hsu HJ, Fuchs E |title=Oct-6: a regulator of keratinocyte gene expression in stratified squamous epithelia. |journal=Mol. Cell. Biol. |volume=14 |issue= 5 |pages= 3263-75 |year= 1994 |pmid= 7909356 |doi=  }}
* {{cite journal | vauthors = Jaegle M, Mandemakers W, Broos L, Zwart R, Karis A, Visser P, Grosveld F, Meijer D | title = The POU factor Oct-6 and Schwann cell differentiation | journal = Science | volume = 273 | issue = 5274 | pages = 507–10 | date = Jul 1996 | pmid = 8662541 | doi = 10.1126/science.273.5274.507 }}
*{{cite journal  | author=Tobler A, Schreiber E, Fontana A |title=The human Oct-6 POU transcription factor lacks the first 50 amino acids of its murine counterpart. |journal=Nucleic Acids Res. |volume=21 |issue= 4 |pages= 1043 |year= 1993 |pmid= 8451175 |doi=  }}
* {{cite journal | vauthors = Sock E, Enderich J, Rosenfeld MG, Wegner M | title = Identification of the nuclear localization signal of the POU domain protein Tst-1/Oct6 | journal = The Journal of Biological Chemistry | volume = 271 | issue = 29 | pages = 17512–8 | date = Jul 1996 | pmid = 8663425 | doi = 10.1074/jbc.271.29.17512 }}
*{{cite journal | author=Abdel-Rahman B, Fiddler M, Rappolee D, Pergament E |title=Expression of transcription regulating genes in human preimplantation embryos. |journal=Hum. Reprod. |volume=10 |issue= 10 |pages= 2787-92 |year= 1996 |pmid= 8567814 |doi= }}
* {{cite journal | vauthors = Malik KF, Jaffe H, Brady J, Young WS | title = The class III POU factor Brn-4 interacts with other class III POU factors and the heterogeneous nuclear ribonucleoprotein U | journal = Brain Research. Molecular Brain Research | volume = 45 | issue = 1 | pages = 99–107 | date = Apr 1997 | pmid = 9105675 | doi = 10.1016/S0169-328X(96)00238-0 }}
*{{cite journal | author=Jaegle M, Mandemakers W, Broos L, ''et al.'' |title=The POU factor Oct-6 and Schwann cell differentiation. |journal=Science |volume=273 |issue= 5274 |pages= 507-10 |year= 1996 |pmid= 8662541 |doi= }}
* {{cite journal | vauthors = Sumiyama K, Washio-Watanabe K, Ono T, Yoshida MC, Hayakawa T, Ueda S | title = Human class III POU genes, POU3F1 and POU3F3, map to chromosomes 1p34.1 and 3p14.2 | journal = Mammalian Genome | volume = 9 | issue = 2 | pages = 180–1 | date = Feb 1998 | pmid = 9457692 | doi = 10.1007/s003359900721 }}
*{{cite journal | author=Sock E, Enderich J, Rosenfeld MG, Wegner M |title=Identification of the nuclear localization signal of the POU domain protein Tst-1/Oct6. |journal=J. Biol. Chem. |volume=271 |issue= 29 |pages= 17512-8 |year= 1996 |pmid= 8663425 |doi= }}
* {{cite journal | vauthors = Arroyo EJ, Bermingham JR, Rosenfeld MG, Scherer SS | title = Promyelinating Schwann cells express Tst-1/SCIP/Oct-6 | journal = The Journal of Neuroscience | volume = 18 | issue = 19 | pages = 7891–902 | date = Oct 1998 | pmid = 9742157 | doi =  }}
*{{cite journal | author=Malik KF, Jaffe H, Brady J, Young WS |title=The class III POU factor Brn-4 interacts with other class III POU factors and the heterogeneous nuclear ribonucleoprotein U. |journal=Brain Res. Mol. Brain Res. |volume=45 |issue= 1 |pages= 99-107 |year= 1997 |pmid= 9105675 |doi= }}
* {{cite journal | vauthors = Kawasaki T, Oka N, Tachibana H, Akiguchi I, Shibasaki H | title = Oct6, a transcription factor controlling myelination, is a marker for active nerve regeneration in peripheral neuropathies | journal = Acta Neuropathologica | volume = 105 | issue = 3 | pages = 203–8 | date = Mar 2003 | pmid = 12557005 | doi = 10.1007/s00401-002-0630-9 }}
*{{cite journal | author=Sumiyama K, Washio-Watanabe K, Ono T, ''et al.'' |title=Human class III POU genes, POU3F1 and POU3F3, map to chromosomes 1p34.1 and 3p14.2. |journal=Mamm. Genome |volume=9 |issue= 2 |pages= 180-1 |year= 1998 |pmid= 9457692 |doi= }}
* {{cite journal | vauthors = Beck IM, Müller M, Mentlein R, Sadowski T, Mueller MS, Paus R, Sedlacek R | title = Matrix metalloproteinase-19 expression in keratinocytes is repressed by transcription factors Tst-1 and Skn-1a: implications for keratinocyte differentiation | journal = The Journal of Investigative Dermatology | volume = 127 | issue = 5 | pages = 1107–14 | date = May 2007 | pmid = 17195013 | doi = 10.1038/sj.jid.5700674 }}
*{{cite journal | author=Arroyo EJ, Bermingham JR, Rosenfeld MG, Scherer SS |title=Promyelinating Schwann cells express Tst-1/SCIP/Oct-6. |journal=J. Neurosci. |volume=18 |issue= 19 |pages= 7891-902 |year= 1998 |pmid= 9742157 |doi=  }}
* {{cite journal | vauthors = Ryu EJ, Wang JY, Le N, Baloh RH, Gustin JA, Schmidt RE, Milbrandt J | title = Misexpression of Pou3f1 results in peripheral nerve hypomyelination and axonal loss | journal = The Journal of Neuroscience | volume = 27 | issue = 43 | pages = 11552–9 | date = Oct 2007 | pmid = 17959798 | doi = 10.1523/JNEUROSCI.5497-06.2007 }}
*{{cite journal | author=Kawasaki T, Oka N, Tachibana H, ''et al.'' |title=Oct6, a transcription factor controlling myelination, is a marker for active nerve regeneration in peripheral neuropathies. |journal=Acta Neuropathol. |volume=105 |issue= 3 |pages= 203-8 |year= 2003 |pmid= 12557005 |doi= 10.1007/s00401-002-0630-9 }}
*{{cite journal | author=Beck IM, Müller M, Mentlein R, ''et al.'' |title=Matrix metalloproteinase-19 expression in keratinocytes is repressed by transcription factors Tst-1 and Skn-1a: implications for keratinocyte differentiation. |journal=J. Invest. Dermatol. |volume=127 |issue= 5 |pages= 1107-14 |year= 2007 |pmid= 17195013 |doi= 10.1038/sj.jid.5700674 }}
*{{cite journal | author=Ryu EJ, Wang JY, Le N, ''et al.'' |title=Misexpression of Pou3f1 results in peripheral nerve hypomyelination and axonal loss. |journal=J. Neurosci. |volume=27 |issue= 43 |pages= 11552-9 |year= 2007 |pmid= 17959798 |doi= 10.1523/JNEUROSCI.5497-06.2007 }}
}}
{{refend}}
{{refend}}


Line 86: Line 29:
* {{MeshName|POU3F1+protein,+human}}
* {{MeshName|POU3F1+protein,+human}}


 
{{gene-1-stub}}
{{protein-stub}}
{{NLM content}}
{{NLM content}}
{{Transcription factors}}
{{Transcription factors|g3}}
[[Category:Transcription factors]]
[[Category:POU-domain proteins]]
{{WikiDoc Sources}}

Revision as of 15:32, 23 November 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

POU domain, class 3, transcription factor 1 (also known as Oct-6) is a protein that in humans is encoded by the POU3F1 gene.[1][2]

See also

References

  1. ↑ Tobler A, Schreiber E, Fontana A (Feb 1993). "The human Oct-6 POU transcription factor lacks the first 50 amino acids of its murine counterpart". Nucleic Acids Research. 21 (4): 1043. doi:10.1093/nar/21.4.1043. PMC 309249. PMID 8451175.
  2. ↑ "Entrez Gene: POU3F1 POU domain, class 3, transcription factor 1".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Retrieved from "https://www.wikidoc.org/index.php?title=POU3F1&oldid=1411317"