Insulinoma history and symptoms: Difference between revisions
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==History and Symptoms== | ==History and Symptoms== | ||
Patient of insulinoma presents usually with the history of hypoglycemic episodes occurring over time with a recent increase in frequency and without any other cause known to cause hypoglycemia like exogenous insulin and hypoglycemic | Patient of insulinoma presents usually with the history of hypoglycemic episodes occurring over time with a recent increase in frequency and without any other cause known to cause [[hypoglycemia]] like exogenous insulin and [[hypoglycemic agent]]<nowiki/>s. The following are the history and symptoms of insulinoma: | ||
===History=== | ===History=== | ||
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*Frequent episodes of altered mental status/confusion | *Frequent episodes of altered mental status/confusion | ||
*Visual disturbances | *Visual disturbances | ||
*Sweating | *[[Sweating]] | ||
*Negative history for exogenous insulin or oral hypoglycemic agents such as Sulfonylureas | *Negative history for exogenous [[insulin]] or oral hypoglycemic agents such as [[Sulfonylureas]] | ||
===Common Symptoms=== | ===Common Symptoms=== | ||
Common symptoms of insulinoma include:<ref name="pmid18703061">{{cite journal| author=Metz DC, Jensen RT| title=Gastrointestinal neuroendocrine tumors: pancreatic endocrine tumors. | journal=Gastroenterology | year= 2008 | volume= 135 | issue= 5 | pages= 1469-92 | pmid=18703061 | doi=10.1053/j.gastro.2008.05.047 | pmc=2612755 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18703061 }} </ref><ref name="pmid9735690">{{cite journal| author=Boukhman MP, Karam JH, Shaver J, Siperstein AE, Duh QY, Clark OH| title=Insulinoma--experience from 1950 to 1995. | journal=West J Med | year= 1998 | volume= 169 | issue= 2 | pages= 98-104 | pmid=9735690 | doi= | pmc=1305178 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9735690 }} </ref> | Common symptoms of insulinoma include:<ref name="pmid18703061">{{cite journal| author=Metz DC, Jensen RT| title=Gastrointestinal neuroendocrine tumors: pancreatic endocrine tumors. | journal=Gastroenterology | year= 2008 | volume= 135 | issue= 5 | pages= 1469-92 | pmid=18703061 | doi=10.1053/j.gastro.2008.05.047 | pmc=2612755 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18703061 }} </ref><ref name="pmid9735690">{{cite journal| author=Boukhman MP, Karam JH, Shaver J, Siperstein AE, Duh QY, Clark OH| title=Insulinoma--experience from 1950 to 1995. | journal=West J Med | year= 1998 | volume= 169 | issue= 2 | pages= 98-104 | pmid=9735690 | doi= | pmc=1305178 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9735690 }} </ref> | ||
*Altered mental status/confusion | *[[Altered mental status]]/[[confusion]] | ||
*Visual disturbances like blurred vision/diplopia | *Visual disturbances like [[blurred vision]]/[[diplopia]] | ||
*Sweating | *[[Sweating]] | ||
*Hyperphagia | *[[Hyperphagia]] | ||
*Coma | *[[Coma]] | ||
===Less Common Symptoms=== | ===Less Common Symptoms=== | ||
Less common symptoms of insulinoma include | Less common symptoms of insulinoma include | ||
*Palpitations | *[[Palpitations]] | ||
*Seizures | *[[Seizures]] | ||
*Tremors | *[[Tremor|Tremors]] | ||
*Behavioral disturbances | *Behavioral disturbances | ||
*Weakness | *[[Weakness]] | ||
{| class="wikitable" style="text-align:center" | {| class="wikitable" style="text-align:center" | ||
| colspan="2" align="center" style="background: #4479BA; color: #FFFFFF; " |'''Neuroglycopenic symptoms''' | | colspan="2" align="center" style="background: #4479BA; color: #FFFFFF; " |'''Neuroglycopenic symptoms''' |
Revision as of 21:10, 16 August 2017
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]
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Overview
The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
History and Symptoms
Patient of insulinoma presents usually with the history of hypoglycemic episodes occurring over time with a recent increase in frequency and without any other cause known to cause hypoglycemia like exogenous insulin and hypoglycemic agents. The following are the history and symptoms of insulinoma:
History
Patients with insulinoma may have a positive history of:
- Frequent episodes of altered mental status/confusion
- Visual disturbances
- Sweating
- Negative history for exogenous insulin or oral hypoglycemic agents such as Sulfonylureas
Common Symptoms
Common symptoms of insulinoma include:[1][2]
- Altered mental status/confusion
- Visual disturbances like blurred vision/diplopia
- Sweating
- Hyperphagia
- Coma
Less Common Symptoms
Less common symptoms of insulinoma include
- Palpitations
- Seizures
- Tremors
- Behavioral disturbances
- Weakness
Neuroglycopenic symptoms | |
Visual disturbances | 59% |
Altered Mental status/Confusion | 75-80% |
Behavioral problems | 36% |
Weakness | 24-32% |
Coma | 47% |
Seizures | 36% |
Sympathetic or Adrenergic symptoms | |
Sweating | 12-69% |
Palpitations | 10-12% |
Tremors | 17-24% |
Hyperphagia/Obesity | 25-50% |
References
- ↑ Metz DC, Jensen RT (2008). "Gastrointestinal neuroendocrine tumors: pancreatic endocrine tumors". Gastroenterology. 135 (5): 1469–92. doi:10.1053/j.gastro.2008.05.047. PMC 2612755. PMID 18703061.
- ↑ Boukhman MP, Karam JH, Shaver J, Siperstein AE, Duh QY, Clark OH (1998). "Insulinoma--experience from 1950 to 1995". West J Med. 169 (2): 98–104. PMC 1305178. PMID 9735690.