Hemorrhagic stroke laboratory findings: Difference between revisions

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==References==
==References==

Revision as of 15:54, 30 November 2016

Hemorrhagic stroke Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Laboratory findings

Blood test Test result Rationale
Complete blood count and platelet
BMP/Osmolarity
  • Increased or decreased serum NA2+, K+, Ca2+
  • Change in osmolarity
PT/APTT/INR[1][2][3]
  • Increased PT/APTT/INR
BUN/Creatinine[4]
  • Increased BUN and creatinine
  • May be associated with poor prognosis in patients with intracerebral hemorrhage and hematoma expansion
Toxicology screen/Serum alcohol level
  • Increased levels of serum
HbA1C
  • Increased levels of HbA1c
Blood glucose levels[5]
  • Increased or decreased levels of blood glucose
Cardiac enzymes[6][7]
  • Increased serum levels of Trop I, Trop T, CK-MB
  • May suggest ongoing myocardial ischemia (left ventricular ischemia)
Pregnancy test
  • Serum and urine B-HCG
  • Rule out pregnancy in all female patients with hemorrhagic stroke

References

  1. Cucchiara B, Messe S, Sansing L, Kasner S, Lyden P, CHANT Investigators (2008). "Hematoma growth in oral anticoagulant related intracerebral hemorrhage". Stroke. 39 (11): 2993–6. doi:10.1161/STROKEAHA.108.520668. PMID 18703803.
  2. Broderick JP, Diringer MN, Hill MD, Brun NC, Mayer SA, Steiner T; et al. (2007). "Determinants of intracerebral hemorrhage growth: an exploratory analysis". Stroke. 38 (3): 1072–5. doi:10.1161/01.STR.0000258078.35316.30. PMID 17290026.
  3. Flaherty ML, Tao H, Haverbusch M, Sekar P, Kleindorfer D, Kissela B; et al. (2008). "Warfarin use leads to larger intracerebral hematomas". Neurology. 71 (14): 1084–9. doi:10.1212/01.wnl.0000326895.58992.27. PMC 2668872. PMID 18824672.
  4. Miller CM, Vespa PM, McArthur DL, Hirt D, Etchepare M (2007). "Frameless stereotactic aspiration and thrombolysis of deep intracerebral hemorrhage is associated with reduced levels of extracellular cerebral glutamate and unchanged lactate pyruvate ratios". Neurocrit Care. 6 (1): 22–9. doi:10.1385/NCC:6:1:22. PMID 17356187.
  5. Sawyer GJ, Fabre JW (1997). "Indirect T-cell allorecognition and the mechanisms of immunosuppression by allogeneic blood transfusions". Transpl Int. 10 (4): 276–83. PMID 9249937.
  6. Davis AM, Natelson BH (1993). "Brain-heart interactions. The neurocardiology of arrhythmia and sudden cardiac death". Tex Heart Inst J. 20 (3): 158–69. PMC 325088. PMID 8219819.
  7. Hasegawa K, Fix ML, Wendell L, Schwab K, Ay H, Smith EE; et al. (2012). "Ischemic-appearing electrocardiographic changes predict myocardial injury in patients with intracerebral hemorrhage". Am J Emerg Med. 30 (4): 545–52. doi:10.1016/j.ajem.2011.02.007. PMC 3684165. PMID 21450435.


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