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{{Solitary pulmonary nodule}}
{{Solitary pulmonary nodule}}
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==Overview==
==Overview==
A '''solitary pulmonary nodule''' ('''SPN''') or '''coin lesion''' is a [[tumor|mass]] in the [[lung]] smaller than 3 centimeters in diameter. It can be an [[incidentaloma|incidental finding]] found in up to 0.2% of [[chest X-ray]]s<ref name="NEJM-cp">{{cite journal |author=Ost D, Fein AM, Feinsilver SH |title=Clinical practice. The solitary pulmonary nodule |journal=N. Engl. J. Med. |volume=348 |issue=25 |pages=2535–42 |year=2003 |month=June |pmid=12815140 |doi=10.1056/NEJMcp012290 |url=http://content.nejm.org/cgi/pmidlookup?view=short&pmid=12815140&promo=ONFLNS19}}</ref> and around 1% of [[CT scan]]s.<ref name="pmid18402653">{{cite journal |author=Alzahouri K, Velten M, Arveux P, Woronoff-Lemsi MC, Jolly D, Guillemin F |title=Management of SPN in France. Pathways for definitive diagnosis of solitary pulmonary nodule: a multicentre study in 18 French districts |journal=BMC Cancer |volume=8 |issue= |pages=93 |year=2008 |pmid=18402653 |pmc=2373300 |doi=10.1186/1471-2407-8-93 |url=http://www.biomedcentral.com/1471-2407/8/93}}</ref>


The nodule most commonly represents a [[benign]] tumor such as a [[granuloma]] or [[hamartoma]], but in around 20% of cases it represents a [[malignant]] [[cancer]],<ref name="pmid18402653">{{cite journal |author=Alzahouri K, Velten M, Arveux P, Woronoff-Lemsi MC, Jolly D, Guillemin F |title=Management of SPN in France. Pathways for definitive diagnosis of solitary pulmonary nodule: a multicentre study in 18 French districts |journal=BMC Cancer |volume=8 |issue= |pages=93 |year=2008 |pmid=18402653 |pmc=2373300 |doi=10.1186/1471-2407-8-93 |url=http://www.biomedcentral.com/1471-2407/8/93}}</ref> especially in [[elderly|older adults]] and [[tobacco smoking|smokers]]. Conversely, 10 to 20% of patients with [[lung cancer]] are diagnosed in this way.<ref name="pmid18402653"/> Thus, the possibility of cancer needs to be excluded through further radiological studies and interventions, possibly including surgical resection. The [[prognosis]] depends on the underlying condition.


'''Solitary pulmonary nodule''' ( also known as '''coin lesion''') is a [[tumor|mass]] in the [[lung]] smaller than 3 centimeters in diameter. In the majority of the cases, solitary pulmonary nodule can be encountered as a [[incidentaloma|incidental finding]] found in up to 0.2% of [[chest X-ray]]s<ref name="NEJM-cp">{{cite journal |author=Ost D, Fein AM, Feinsilver SH |title=Clinical practice. The solitary pulmonary nodule |journal=N. Engl. J. Med. |volume=348 |issue=25 |pages=2535–42 |year=2003 |month=June |pmid=12815140 |doi=10.1056/NEJMcp012290 |url=http://content.nejm.org/cgi/pmidlookup?view=short&pmid=12815140&promo=ONFLNS19}}</ref> and around 1% of [[CT scan]]s.<ref name="pmid18402653">{{cite journal |author=Alzahouri K, Velten M, Arveux P, Woronoff-Lemsi MC, Jolly D, Guillemin F |title=Management of SPN in France. Pathways for definitive diagnosis of solitary pulmonary nodule: a multicentre study in 18 French districts |journal=BMC Cancer |volume=8 |issue= |pages=93 |year=2008 |pmid=18402653 |pmc=2373300 |doi=10.1186/1471-2407-8-93 |url=http://www.biomedcentral.com/1471-2407/8/93}}</ref> The nodule most commonly represents a [[benign]] tumor such as a [[granuloma]] or [[hamartoma]], but in around 20% of cases it represents a [[malignant]] [[cancer]],<ref name="pmid18402653">{{cite journal |author=Alzahouri K, Velten M, Arveux P, Woronoff-Lemsi MC, Jolly D, Guillemin F |title=Management of SPN in France. Pathways for definitive diagnosis of solitary pulmonary nodule: a multicentre study in 18 French districts |journal=BMC Cancer |volume=8 |issue= |pages=93 |year=2008 |pmid=18402653 |pmc=2373300 |doi=10.1186/1471-2407-8-93 |url=http://www.biomedcentral.com/1471-2407/8/93}}</ref> especially in [[elderly|older adults]] and [[tobacco smoking|smokers]]. Conversely, 10 to 20% of patients with [[lung cancer]] are diagnosed in this way.<ref name="pmid18402653"/> Thus, the possibility of cancer needs to be excluded through further radiological studies and interventions, possibly including surgical resection. The [[prognosis]] depends on the underlying condition.
==Historical Perspective==
==Pathophysiology==
==Causes==
==Differentiating Squamous Cell Carcinoma of the Lung from other Diseases==
==Epidemiology and Demographics==
==Risk Factors==
==Screening==
==Natural History, Complications and Prognosis==
==Diagnosis==
===Staging===
===History and Symptoms===
===Physical Examination===
===Laboratory Findings===
===Chest X Ray===
===CT===
===MRI===
===Ultrasound===
===Other Imaging Findings===
===Other Diagnostic Studies===
===Biopsy===
==Treatment==
===Medical Therapy===
===Radiation Therapy===
===Surgery===
==Prevention==


==References==
==References==
{{reflist|2}}
{{Reflist|2}}


{{WH}}
[[Category:Pulmonology]]
{{WS}}


[[Category:Disease]]
[[Category:Disease]]
[[Category:Pulmonology]]
 
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Revision as of 14:44, 14 March 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

Solitary pulmonary nodule ( also known as coin lesion) is a mass in the lung smaller than 3 centimeters in diameter. In the majority of the cases, solitary pulmonary nodule can be encountered as a incidental finding found in up to 0.2% of chest X-rays[1] and around 1% of CT scans.[2] The nodule most commonly represents a benign tumor such as a granuloma or hamartoma, but in around 20% of cases it represents a malignant cancer,[2] especially in older adults and smokers. Conversely, 10 to 20% of patients with lung cancer are diagnosed in this way.[2] Thus, the possibility of cancer needs to be excluded through further radiological studies and interventions, possibly including surgical resection. The prognosis depends on the underlying condition.


Historical Perspective

Pathophysiology

Causes

Differentiating Squamous Cell Carcinoma of the Lung from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging

History and Symptoms

Physical Examination

Laboratory Findings

Chest X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Biopsy

Treatment

Medical Therapy

Radiation Therapy

Surgery

Prevention

References

  1. Ost D, Fein AM, Feinsilver SH (2003). "Clinical practice. The solitary pulmonary nodule". N. Engl. J. Med. 348 (25): 2535–42. doi:10.1056/NEJMcp012290. PMID 12815140. Unknown parameter |month= ignored (help)
  2. 2.0 2.1 2.2 Alzahouri K, Velten M, Arveux P, Woronoff-Lemsi MC, Jolly D, Guillemin F (2008). "Management of SPN in France. Pathways for definitive diagnosis of solitary pulmonary nodule: a multicentre study in 18 French districts". BMC Cancer. 8: 93. doi:10.1186/1471-2407-8-93. PMC 2373300. PMID 18402653.


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