MALT lymphoma medical therapy: Difference between revisions
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{{MALT lymphoma}} | {{MALT lymphoma}} | ||
{{CMG}} | {{CMG}}{{AE}}{{SR}} | ||
==Overview== | ==Overview== | ||
==Medical therapy== | ==Medical therapy== | ||
The various treatment options for MALT lymphoma include: | |||
{{familytree/start |summary=Treatment of MALT lymphoma}} | |||
{{familytree |boxstyle=background: #DCDCDC;| | | | | | | | | | | | | A01| | | | | | | | | | | | | |A01=<div style="width: 12em; padding:0.2em;">'''Treatment of MALT lymphoma'''</div>}} | |||
{{familytree |boxstyle=background: #DCDCDC;| | | | | | | |,|-|-|-|-|-|^|-|-|-|-|-|.| | | | | | | | | | | | | | |}} | |||
{{familytree |boxstyle=background: #DCDCDC;| | | | | | | B01 | | | | | | | | | | B02 | | | | | | | | | | | | | | | |B01=<div style="width: 12em; padding:0em;">'''Early stage<br>(localized)<br>''' </div>|B02=<div style="width: 12em; padding:0em;">'''Advanced stage'''</div>}} | |||
{{familytree |boxstyle=background: #DCDCDC;| | | | | | | F01 | | | | | | | | | | F02 | | | | | | | | | | | | | | | |F01=<div style="width: 12em; padding:0em;">'''WHO grade I / II''' </div>|F02=<div style="width: 12em; padding:0em;">'''WHO grade II'''</div>}} | |||
{{familytree |boxstyle=background: #DCDCDC;| | | | | | | |!| | | | | |,|-|-|-|v|-|^|-|v|-|-|-|.| | | | | | | | | | | | | | |}} | |||
{{familytree |boxstyle=background: #DCDCDC;| | | | | | | |!| | | | | C01 | | C02 | | C03 | | C04 | | | | | | | | | | | | | |C01=<div style="width: 9em; padding:0.2em;">'''[[Fibrillary astrocytoma]]''' </div>|C02=<div style="width: 9em; padding:0.2em;">'''[[Gemistocytic astrocytoma]]'''</div>|C03=<div style="width: 9em; padding:0.2em;">'''[[Protoplasmic astrocytoma]]'''</div>|C04=<div style="width: 9em; padding:0.2em;">'''[[Oligoastrocytoma]]'''</div>}} | |||
{{familytree |boxstyle=background: #DCDCDC;| |,|-|-|-|v|-|^|-|v|-|-|-|.| | | | | | | | | | | | | | | | | |}} | |||
{{familytree |boxstyle=background: #DCDCDC;| D01 | | D02 | | D03 | | D04 | | | | | | | | | | | | | | | | | | | | |D01=<div style="width: 9em; padding:0.2em;">'''[[Pilocytic astrocytoma]]''' </div>|D02=<div style="width: 9em; padding:0.2em;">'''Pilomyxoid astrocytoma'''</div>|D03=<div style="width: 9em; padding:0.2em;">'''[[Subependymal giant cell astrocytoma]]'''</div>|D04=<div style="width: 9em; padding:0.2em;">'''[[Pleomorphic xanthoastrocytoma]]'''</div>}} | |||
{{familytree |boxstyle=background: #DCDCDC;| E01 | | E02 | | E03 | | E04 | | | | | | | | | | | | | | | | | | | | |E01=<div style="width: 9em; padding:0.2em;">'''WHO grade I''' </div>|E02=<div style="width: 9em; padding:0.2em;">'''WHO grade II'''</div>|E03=<div style="width: 9em; padding:0.2em;">'''WHO grade I'''</div>|E04=<div style="width: 9em; padding:0.2em;">'''WHO grade II'''</div>}} | |||
{{familytree/end}} | |||
If the disease is limited to the stomach (which is assessed with [[computed tomography]]), then 70-80% of patients will have a complete regression on treatment with [[antibiotic]] eradication of ''H. pylori''. <ref>{{cite journal | author = Bayerdörffer E, Neubauer A, Rudolph B, Thiede C, Lehn N, Eidt S, Stolte M | title = Regression of primary gastric lymphoma of mucosa-associated lymphoid tissue type after cure of Helicobacter pylori infection. MALT Lymphoma Study Group. | journal = Lancet | volume = 345 | issue = 8965 | pages = 1591-4 | year = 1995 | id = PMID 7783535}}</ref> | If the disease is limited to the stomach (which is assessed with [[computed tomography]]), then 70-80% of patients will have a complete regression on treatment with [[antibiotic]] eradication of ''H. pylori''. <ref>{{cite journal | author = Bayerdörffer E, Neubauer A, Rudolph B, Thiede C, Lehn N, Eidt S, Stolte M | title = Regression of primary gastric lymphoma of mucosa-associated lymphoid tissue type after cure of Helicobacter pylori infection. MALT Lymphoma Study Group. | journal = Lancet | volume = 345 | issue = 8965 | pages = 1591-4 | year = 1995 | id = PMID 7783535}}</ref> | ||
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[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category: | [[Category:Oncology]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} |
Revision as of 17:26, 25 January 2016
MALT lymphoma Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Medical therapy
The various treatment options for MALT lymphoma include:
Treatment of MALT lymphoma | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Early stage (localized) | Advanced stage | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
WHO grade I / II | WHO grade II | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Pilomyxoid astrocytoma | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
WHO grade I | WHO grade II | WHO grade I | WHO grade II | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
If the disease is limited to the stomach (which is assessed with computed tomography), then 70-80% of patients will have a complete regression on treatment with antibiotic eradication of H. pylori. [1]
Radiotherapy
Others may be effectively controlled with the use of radiotherapy, or surgery. Both modalities may be curative in localized disease.
Chemotherapy
In contrast, if the disease has spread or has been refractory on antibiotics, chemotherapy may need to be considered.
References
- ↑ Bayerdörffer E, Neubauer A, Rudolph B, Thiede C, Lehn N, Eidt S, Stolte M (1995). "Regression of primary gastric lymphoma of mucosa-associated lymphoid tissue type after cure of Helicobacter pylori infection. MALT Lymphoma Study Group". Lancet. 345 (8965): 1591–4. PMID 7783535.