Glioma classification: Difference between revisions
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==Overview== | ==Overview== | ||
Glioma may be classified into several subtypes based on the type of cell, grade, and location. | Glioma may be classified into several subtypes based on the type of cell, grade, and location. | ||
==Classification== | ==Classification== | ||
Glioma may be classified into several subtypes based on the type of cell, grade, and location. | Glioma may be classified into several subtypes based on the type of cell, grade, and location. | ||
===Based on the type of cell=== | |||
=== | Glioma may be classified according to the type of cell into four subtypes: | ||
* [[Ependymoma]]s — [[ependymal cell]]s | * [[Ependymoma]]s — [[ependymal cell]]s | ||
* [[Astrocytoma]]s — [[astrocyte]]s | * [[Astrocytoma]]s — [[astrocyte]]s | ||
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* Mixed gliomas, such as [[oligoastrocytomas]], contain cells from different types of glia. | * Mixed gliomas, such as [[oligoastrocytomas]], contain cells from different types of glia. | ||
=== | ===Based on the grade=== | ||
Glioma may be classified according to the grade into two subtypes: | |||
* '''Low-grade''' gliomas are well-differentiated (not anaplastic); these are [[cancer|benign]] | |||
* '''Low-grade''' gliomas are well-differentiated (not anaplastic); these are [[cancer|benign]] | * '''High-grade''' gliomas are undifferentiated or [[anaplastic]]; these are [[cancer|malignant]] | ||
* '''High-grade''' gliomas are undifferentiated or [[anaplastic]]; these are [[cancer|malignant]] | |||
=== | ====WHO grading system for astrocytomas==== | ||
*WHO Grade 1 — e.g., [[pilocytic astrocytoma]] | |||
*WHO Grade 2 — e.g., diffuse or low-grade astrocytoma | |||
*WHO Grade 3 — e.g., [[anaplastic]] ([[cancer|malignant]]) astrocytoma | |||
*WHO Grade 4 — [[glioblastoma multiforme]] (most common glioma in adults) | |||
* [[ | ===Based on the location=== | ||
* [[ | Glioma may be classified according to the location into two subtypes: | ||
* [[Infratentorial]] : mostly in children (70%) | |||
* [[Supratentorial]] : mostly in adults (70%) | |||
==References== | ==References== | ||
Revision as of 03:22, 20 September 2015
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Glioma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Glioma classification On the Web |
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American Roentgen Ray Society Images of Glioma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]Sujit Routray, M.D. [3]
Overview
Glioma may be classified into several subtypes based on the type of cell, grade, and location.
Classification
Glioma may be classified into several subtypes based on the type of cell, grade, and location.
Based on the type of cell
Glioma may be classified according to the type of cell into four subtypes:
- Ependymomas — ependymal cells
- Astrocytomas — astrocytes
- Oligodendrogliomas — oligodendrocytes
- Mixed gliomas, such as oligoastrocytomas, contain cells from different types of glia.
Based on the grade
Glioma may be classified according to the grade into two subtypes:
- Low-grade gliomas are well-differentiated (not anaplastic); these are benign
- High-grade gliomas are undifferentiated or anaplastic; these are malignant
WHO grading system for astrocytomas
- WHO Grade 1 — e.g., pilocytic astrocytoma
- WHO Grade 2 — e.g., diffuse or low-grade astrocytoma
- WHO Grade 3 — e.g., anaplastic (malignant) astrocytoma
- WHO Grade 4 — glioblastoma multiforme (most common glioma in adults)
Based on the location
Glioma may be classified according to the location into two subtypes:
- Infratentorial : mostly in children (70%)
- Supratentorial : mostly in adults (70%)