Multiple endocrine neoplasia type 1 MRI: Difference between revisions
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[[MRI]] may be helpful in the [[diagnosis]] of multiple endocrine neoplasia type 1. | [[MRI]] may be helpful in the [[diagnosis]] of multiple endocrine neoplasia type 1. | ||
==MRI== | ==MRI== | ||
===Gastrointestinal Neuroendocrine Tumors<ref name=Radiopaedia012015>{{cite web | title = Radiopedia2015 Gastrointestinal neuroendocrine tumours [Dr Dalia Ibrahim and Dr Jan Smith]| url = http://radiopaedia.org/articles/gastrointestinal-neuroendocrine-tumours-3 }}</ref> | ===Gastrointestinal Neuroendocrine Tumors=== | ||
* [[MRI]] is used for suspected hepatic, pancreatic or retroperitoneal [[neuroendocrine tumor]]s, often with [[gadolinium]] contrast. | * MRI findings of gastrointestinal neuroendocrine tumors include the following:<ref name=Radiopaedia012015>{{cite web | title = Radiopedia2015 Gastrointestinal neuroendocrine tumours [Dr Dalia Ibrahim and Dr Jan Smith]| url = http://radiopaedia.org/articles/gastrointestinal-neuroendocrine-tumours-3 }}</ref> | ||
* [[MRI]] enterography is also possible. | :* [[MRI]] is used for suspected hepatic, pancreatic or retroperitoneal [[neuroendocrine tumor]]s, often with [[gadolinium]] contrast. | ||
:* [[MRI]] enterography is also possible. | |||
===Insulinoma<ref name=Radiopaedia032015>{{cite web | title = Radiopedia2015 Insulinoma [Dr Yuranga Weerakkody and Dr Frank Gaillard]| url = http://radiopaedia.org/articles/insulinoma }}</ref> | ===Insulinoma=== | ||
* Dynamic [[MRI]] with fast gradient echo sequences following [[bolus]] [[injection]] of [[contrast]] medium may aid the detection of these [[tumor]]s<ref name="pmid11675319">{{cite journal| author=Owen NJ, Sohaib SA, Peppercorn PD, Monson JP, Grossman AB, Besser GM et al.| title=MRI of pancreatic neuroendocrine tumours. | journal=Br J Radiol | year= 2001 | volume= 74 | issue= 886 | pages= 968-73 | pmid=11675319 | doi=10.1259/bjr.74.886.740968 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11675319 }} </ref> | * MRI findings of insulinoma include the following:<ref name=Radiopaedia032015>{{cite web | title = Radiopedia2015 Insulinoma [Dr Yuranga Weerakkody and Dr Frank Gaillard]| url = http://radiopaedia.org/articles/insulinoma }}</ref> | ||
* '''T1 C+ (Gd)''': typically shows enhancement, although [[contrast]] enhancement may not improve [[tumor]] visualisation compared with non-[[contrast]] images | :* Dynamic [[MRI]] with fast gradient echo sequences following [[bolus]] [[injection]] of [[contrast]] medium may aid the detection of these [[tumor]]s<ref name="pmid11675319">{{cite journal| author=Owen NJ, Sohaib SA, Peppercorn PD, Monson JP, Grossman AB, Besser GM et al.| title=MRI of pancreatic neuroendocrine tumours. | journal=Br J Radiol | year= 2001 | volume= 74 | issue= 886 | pages= 968-73 | pmid=11675319 | doi=10.1259/bjr.74.886.740968 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11675319 }} </ref> | ||
===Somatostatinoma<ref name=Radiopaedia072015>{{cite web | title = Radiopedia2015 Somatostatinoma [Dr Yuranga Weerakkody]| url = http://radiopaedia.org/articles/somatostatinoma }}</ref> | :* '''T1 C+ (Gd)''': typically shows enhancement, although [[contrast]] enhancement may not improve [[tumor]] visualisation compared with non-[[contrast]] images | ||
===Somatostatinoma=== | |||
* MRI findings of insulinoma include the following:<ref name=Radiopaedia072015>{{cite web | title = Radiopedia2015 Somatostatinoma [Dr Yuranga Weerakkody]| url = http://radiopaedia.org/articles/somatostatinoma }}</ref> | |||
* Smaller [[lesion]]s may be difficult to [[diagnose]]. | * Smaller [[lesion]]s may be difficult to [[diagnose]]. | ||
* Signal characteristics of larger lesion include: | * Signal characteristics of larger lesion include: |
Revision as of 19:11, 18 September 2015
Multiple endocrine neoplasia type 1 Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
MRI may be helpful in the diagnosis of multiple endocrine neoplasia type 1.
MRI
Gastrointestinal Neuroendocrine Tumors
- MRI findings of gastrointestinal neuroendocrine tumors include the following:[1]
- MRI is used for suspected hepatic, pancreatic or retroperitoneal neuroendocrine tumors, often with gadolinium contrast.
- MRI enterography is also possible.
Insulinoma
- MRI findings of insulinoma include the following:[2]
Somatostatinoma
- MRI findings of insulinoma include the following:[4]
- Smaller lesions may be difficult to diagnose.
- Signal characteristics of larger lesion include:
- T1: low signal 1,8
- T2: high signal 1,8
- T1 (C+) Gd: most show early diffuse heterogenous enhancement
Reference
- ↑ "Radiopedia2015 Gastrointestinal neuroendocrine tumours [Dr Dalia Ibrahim and Dr Jan Smith]".
- ↑ "Radiopedia2015 Insulinoma [Dr Yuranga Weerakkody and Dr Frank Gaillard]".
- ↑ Owen NJ, Sohaib SA, Peppercorn PD, Monson JP, Grossman AB, Besser GM; et al. (2001). "MRI of pancreatic neuroendocrine tumours". Br J Radiol. 74 (886): 968–73. doi:10.1259/bjr.74.886.740968. PMID 11675319.
- ↑ "Radiopedia2015 Somatostatinoma [Dr Yuranga Weerakkody]".