Glioblastoma multiforme MRI: Difference between revisions
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**Elevated signal on DWI is common in solid / enhancing component | **Elevated signal on DWI is common in solid / enhancing component | ||
**Diffusion restriction is typically intermediate similar to normal [[white matter]], but significantly elevated compared to surrounding vasogenic [[edema]] (which has facilitated diffusion) | **Diffusion restriction is typically intermediate similar to normal [[white matter]], but significantly elevated compared to surrounding vasogenic [[edema]] (which has facilitated diffusion) | ||
*ADC values correlate with grade: | |||
**WHO IV (GBM) = 745 ± 135 x 10-6 mm2/s | **WHO IV (GBM) = 745 ± 135 x 10-6 mm2/s | ||
**WHO III (anaplastic) = 1067 ± 276 x 10-6 mm2/s | **WHO III (anaplastic) = 1067 ± 276 x 10-6 mm2/s | ||
**WHO II (low grade) = 1273 ± 293 x 10-6 mm2/s | **WHO II (low grade) = 1273 ± 293 x 10-6 mm2/s | ||
**ADC threshold value of 1185 x 10-6 mm2/s sensitivity (97.6%) and specificity (53.1%) in the discrimination of high-grade (WHO grade III & IV) and low-grade (WHO grade II) gliomas | **ADC threshold value of 1185 x 10-6 mm2/s sensitivity (97.6%) and specificity (53.1%) in the discrimination of high-grade (WHO grade III & IV) and low-grade (WHO grade II) gliomas | ||
*Non-enhancing necrotic / cystic component | |||
**Majority (>90%) have facilitated diffusion (ADC values > 1000 x 10-6 mm2/s) | **Majority (>90%) have facilitated diffusion (ADC values > 1000 x 10-6 mm2/s) | ||
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Revision as of 14:11, 15 September 2015
Glioblastoma multiforme Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Glioblastoma multiforme MRI On the Web |
American Roentgen Ray Society Images of Glioblastoma multiforme MRI |
Risk calculators and risk factors for Glioblastoma multiforme MRI |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
MRI
Brain MRI is helpful in the diagnosis of glioblastoma. On brain MRI, glioblastoma is characterized by:[1]
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Patient #1: Presented with increasing headaches
Patient #2
References
- ↑ XYZ of glioblastoma multiforme. Dr Dylan Kurda and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/glioblastoma