Glioblastoma multiforme pathophysiology: Difference between revisions
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==Pathophysiology== | ==Pathophysiology== | ||
===Microscopic Pathology=== | ===Microscopic Pathology=== | ||
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Revision as of 17:44, 12 September 2015
Glioblastoma multiforme Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology
Microscopic Pathology
Genetics
- Almost all cases of GBM are sporadic, without a familial predilection, although chromosomal aberrations such as PTEN mutation, and p53 mutation are commonly seen in these tumors.
- Growth factor aberrant signaling associated with EGFR, and PDGF are also seen.