Multiple endocrine neoplasia type 1 epidemiology and demographics: Difference between revisions
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* Men and women are affected equally by multiple endocrine neoplasia type 1.<ref name="pmiddoi:10.1016/j.beem.2010.07.003">{{cite journal| author=Schmoldt A, Benthe HF, Haberland G| title=Digitoxin metabolism by rat liver microsomes. | journal=Biochem Pharmacol | year= 1975 | volume= 24 | issue= 17 | pages= 1639-41 | pmid=doi:10.1016/j.beem.2010.07.003 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10 }} </ref> | * Men and women are affected equally by multiple endocrine neoplasia type 1.<ref name="pmiddoi:10.1016/j.beem.2010.07.003">{{cite journal| author=Schmoldt A, Benthe HF, Haberland G| title=Digitoxin metabolism by rat liver microsomes. | journal=Biochem Pharmacol | year= 1975 | volume= 24 | issue= 17 | pages= 1639-41 | pmid=doi:10.1016/j.beem.2010.07.003 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10 }} </ref><ref name="pmid21551167">{{cite journal| author=Goudet P, Bonithon-Kopp C, Murat A, Ruszniewski P, Niccoli P, Ménégaux F et al.| title=Gender-related differences in MEN1 lesion occurrence and diagnosis: a cohort study of 734 cases from the Groupe d'etude des Tumeurs Endocrines. | journal=Eur J Endocrinol | year= 2011 | volume= 165 | issue= 1 | pages= 97-105 | pmid=21551167 | doi=10.1530/EJE-10-0950 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21551167 }} </ref> | ||
* Males have a higher incidence of pancreatic tumors. | * Males have a higher incidence of pancreatic tumors. | ||
* Females have a higher incidence of pituitary tumors. | * Females have a higher incidence of pituitary tumors. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [3]
Overview
Epidemiology and Demographics
Prevalence
- Worldwide, the prevalence of multiple endocrine neoplasia type 1 is estimated to be 2-3 per 100,000.[1]
- Multiple endocrine neoplasia type 1 is a rare disease that occurs in approximately one in 30,000 individuals.
Age
- Endocrine and non-endocrine manifestations of the disease in MEN1 patients most often begin in the fourth or fifth decade. The onset of the disease is rare before age 10 years.[2]
Gender
- Men and women are affected equally by multiple endocrine neoplasia type 1.[2][3]
- Males have a higher incidence of pancreatic tumors.
- Females have a higher incidence of pituitary tumors.
- Thymic tumors are found in men.
Race
- The prevalence of multiple endocrine neoplasia type 1 does not vary by race.
Geographic Distribution
- There is no geographic preferences for the incidence of multiple endocrine neoplasia type 1.
References
- ↑ [1] C. Romei, E. Pardi, F. Cetani, and R. Elisei, “Genetic and Clinical Features of Multiple Endocrine Neoplasia Types 1 and 2,” Journal of Oncology, vol. 2012, Article ID 705036, 15 pages, 2012. doi:10.1155/2012/705036
- ↑ 2.0 2.1 Schmoldt A, Benthe HF, Haberland G (1975). "Digitoxin metabolism by rat liver microsomes". Biochem Pharmacol. 24 (17): 1639–41. PMID doi:10.1016/j.beem.2010.07.003 Check
|pmid=value (help). - ↑ Goudet P, Bonithon-Kopp C, Murat A, Ruszniewski P, Niccoli P, Ménégaux F; et al. (2011). "Gender-related differences in MEN1 lesion occurrence and diagnosis: a cohort study of 734 cases from the Groupe d'etude des Tumeurs Endocrines". Eur J Endocrinol. 165 (1): 97–105. doi:10.1530/EJE-10-0950. PMID 21551167.