Multiple endocrine neoplasia type 1 epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [3]

Prevalence

• Worldwide, the prevalence of multiple endocrine neoplasia type 1 is estimated to be 2-3 per 100,000.
• Multiple endocrine neoplasia type 1 is a rare disease that occurs in approximately one in 30,000 individuals.

Age

• Endocrine and non-endocrine manifestations of the disease in MEN1 patients most often begin in the fourth or fifth decade. The onset of the disease is rare before age 10 years.

Gender

• Men and women are affected equally by multiple endocrine neoplasia type 1.
• Males have a higher incidence of pancreatic tumors.
• Females have a higher incidence of pituitary tumors.
• Thymic tumors are found in men.

Race

• The prevalence of multiple endocrine neoplasia type 1 does not vary by race.

Geographic Distribution

• There is no geographic preferences for the incidence of multiple endocrine neoplasia type 1.

References

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