Multiple endocrine neoplasia type 1 differential diagnosis: Difference between revisions
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Multiple endocrine neoplasia type 1 must be differentiated from other diseases that cause [[hyperparathyroiodism]], [[gastric ulcer]]s, and neurological symptoms such as [[von Hippel-Lindau syndrome]], [[tuberous sclerosis]], [[carney complex]], [[neurofibromatosis type 1]], [[Li-Fraumeni syndrome]], [[multiple endocrine neoplasia type 2]], [[familial hyperparathyroidism]], [[pheochromocytoma]] and [[acromegaly]]. | Multiple endocrine neoplasia type 1 must be differentiated from other diseases that cause [[hyperparathyroiodism]], [[gastric ulcer]]s, and neurological symptoms such as [[von Hippel-Lindau syndrome]], [[tuberous sclerosis]], [[carney complex]], [[neurofibromatosis type 1]], [[Li-Fraumeni syndrome]], [[multiple endocrine neoplasia type 2]], [[familial hyperparathyroidism]], [[pheochromocytoma]] and [[acromegaly]]. | ||
==Differential Diagnosis | ==Differential Diagnosis== | ||
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| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |[[ | | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |[[Thyroid carcinoma]] | ||
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| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |[[ | | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |[[Pheochromocytoma]]/[[paraganglioma]] | ||
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| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |[[ | | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |[[Adrenocortical carcinoma]] | ||
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| style="padding: 5px 5px; background: #F5F5F5;" colspan="2"|<small>Adapted from | | style="padding: 5px 5px; background: #F5F5F5;" colspan="2"|<small>Adapted from Toledo SP, Lourenço DM, Toledo RA A differential diagnosis of inherited endocrine tumors and their tumor counterparts.<ref name="pmid23917672">{{cite journal| author=Toledo SP, Lourenço DM, Toledo RA| title=A differential diagnosis of inherited endocrine tumors and their tumor counterparts. | journal=Clinics (Sao Paulo) | year= 2013 | volume= 68 | issue= 7 | pages= 1039-56 | pmid=23917672 | doi=10.6061/clinics/2013(07)24 | pmc=PMC3715026 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23917672 }} </ref> </small> | ||
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==Reference== | ==Reference== | ||
{{Reflist}} | {{Reflist}} |
Revision as of 03:01, 8 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Multiple endocrine neoplasia type 1 must be differentiated from other diseases that cause hyperparathyroiodism, gastric ulcers, and neurological symptoms such as von Hippel-Lindau syndrome, tuberous sclerosis, carney complex, neurofibromatosis type 1, Li-Fraumeni syndrome, multiple endocrine neoplasia type 2, familial hyperparathyroidism, pheochromocytoma and acromegaly.
Differential Diagnosis
Disease | Definition |
---|---|
von Hippel-Lindau syndrome | Autosomal dominant genetic disorder causing abnormal growth of blood vessels in different parts of the body. |
Tuberous sclerosis | A rare multi-system genetic disease that causes benign tumors to grow in the brain and on other vital organs such as the kidneys, heart, eyes, lungs, and skin |
Carney complex | Autosomal dominant conditions comprising myxomas of the heart and skin, hyperpigmentation of the skin (lentiginosis), and endocrine overactivity. |
Neurofibromatosis type 1 | |
Li-Fraumeni syndrome | |
Gardner syndrome | |
Multiple endocrine neoplasia type 2 | |
Cowden syndrome | |
Cushing's syndrome | |
Acromegaly/gigantism | |
Aldosteronoma | |
Pituitary adenoma | |
Hyperparathyroidism | |
Thyroid carcinoma | |
Pheochromocytoma/paraganglioma | |
Adrenocortical carcinoma | |
Adapted from Toledo SP, Lourenço DM, Toledo RA A differential diagnosis of inherited endocrine tumors and their tumor counterparts.[1] |
Reference
- ↑ Toledo SP, Lourenço DM, Toledo RA (2013). "A differential diagnosis of inherited endocrine tumors and their tumor counterparts". Clinics (Sao Paulo). 68 (7): 1039–56. doi:10.6061/clinics/2013(07)24. PMC 3715026. PMID 23917672.