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==Overview==
==Overview==

Revision as of 16:04, 18 August 2015

Peutz-Jeghers syndrome Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Overview

Pathophysiology

Genetics

In 1998, a gene was found to be associated with the mutation. On chromosome 19, the gene known as STK11 (LKB1)[1] is a possible tumor suppressor gene. It is inherited in an Autosomal Dominant pattern (see Mendelian inheritance) which means that anyone who has PJS has a 50% chance of passing it onto their children.

References

  1. "UniProtKB/Swiss-Prot entry Q15831 [STK11_HUMAN] Serine/threonine-protein kinase 11". Retrieved 2007-07-21.

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