Donovanosis laboratory findings: Difference between revisions

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* Tests that may be done include:
* Tests that may be done include:
**Culture of tissue sample (hard to do and not routinely available)
**[[Culture]] of tissue sample: Culture of C. granulomatis is difficult to perform and not routinely available.
**Scrapings or [[punch biopsy]] of lesion
**Scrapings or [[punch biopsy]] of lesion: Diagnosis requires visualization of [[Donovan bodies]] (numerous bacilli in the cytoplasm of [[macrophage]] demonstrated with [[Giemsa stain|Giemsa]] or [[Wright’s stain]]) in smears of scrapings from the ulcer base or histologic sections.


*Laboratory tests, such as those used to detect [[syphilis]], are available only on a research basis for diagnosing donovanosis.
*Laboratory tests, such as those used to detect [[syphilis]], are available only on a research basis for diagnosing donovanosis.
==References==
==References==
<references/>
<references/>

Revision as of 15:37, 30 November 2012

Donovanosis Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2]

Overview

Laboratory Findings

  • It may be donovanosis if genital sores have been present for a long time and have been spreading.
  • Tests that may be done include:
    • Culture of tissue sample: Culture of C. granulomatis is difficult to perform and not routinely available.
    • Scrapings or punch biopsy of lesion: Diagnosis requires visualization of Donovan bodies (numerous bacilli in the cytoplasm of macrophage demonstrated with Giemsa or Wright’s stain) in smears of scrapings from the ulcer base or histologic sections.
  • Laboratory tests, such as those used to detect syphilis, are available only on a research basis for diagnosing donovanosis.

References


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