Polycystic kidney disease natural history: Difference between revisions

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Revision as of 23:26, 16 November 2013

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]

@@ Line 3: / Line 3: @@
 ==Overview==
-Polycystic kidney disease is a multiorgan and progressive disorder characterized by formation of [[cyst]]s in [[kidney]] and other organs like [[pancreas]], [[liver]] and [[spleen]].
-==Natural History==
-*Symptoms of polycystic kidney disease begin in the third or fourth decade of life. However, the renal [[cyst]]s can be detected as early as childhood or in utero.
-*The [[cyst]]s gradually grow in size replacing most of the renal tissue, compromising its normal function.
-*[[Creatinine]] begins to built up and the patient eventually goes into [[end stage renal disease]].
-==Complications==
+==Natural History, Prognosis, and Complications==
-*[[Anemia]]
-*Rupture of [[cyst]]s
-*Infection of liver [[cyst]]s
-*[[Chronic renal failure]]
-*[[Hypertension]]
-*[[Nephrolithiasis]]
-*[[Liver failure]]
-*[[Urinary tract infection]]
-==Prognosis==
-*The disease gets worse slowly. Eventually it leads to end-stage [[chronic renal failure]].
-*It is also associated with liver disease, including infection of liver [[cyst]]s.
-*Medical treatment may relieve symptoms for many years.
-*People with PKD who do not have other diseases may be good candidates for a kidney transplant.
 ==References==