Acromegaly resident survival guide: Difference between revisions

Jump to navigation Jump to search
Line 23: Line 23:
The approach to diagnosis of [[Acromegaly]] is based on a step-wise testing strategy. Below is an algorithm summarising the identification and laboratory diagnosis of [[Acromegaly]].
The approach to diagnosis of [[Acromegaly]] is based on a step-wise testing strategy. Below is an algorithm summarising the identification and laboratory diagnosis of [[Acromegaly]].
{{familytree/start |summary=Acromegaly.}}
{{familytree/start |summary=Acromegaly.}}
{{familytree | | | | | | | | | | | | | A01 | | | A01=<div style="float: left; text-align: left; width: 20em; padding:1em;">'''Characterize the symptoms:''' <br> ❑ [[Headaches]]<br> ❑ [[Lethargy]] <br> ❑ [[Hyperhidrosis]]<br> ❑ [[Lethargy]]<br> ❑ [[Paraesthesia]]<br> ❑ [[Sexual dysfunction]]<ref name="pmid1521514">{{cite journal| author=Molitch ME| title=Clinical manifestations of acromegaly. | journal=Endocrinol Metab Clin North Am | year= 1992 | volume= 21 | issue= 3 | pages= 597-614 | pmid=1521514 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1521514  }} </ref></div> }}
{{familytree | | | | | | | | | | | | | A01 | | | A01=<div style="float: left; text-align: left; width: 20em; padding:1em;">'''Characterize the symptoms:''' <br> ❑ [[Headaches]]<br> ❑ [[Lethargy]] <br> ❑ [[Hyperhidrosis]] (excessive sweating)<br> ❑ [[Lethargy]]<br> ❑ [[Paraesthesia]]<br> ❑ [[Sexual dysfunction]]<ref name="pmid1521514">{{cite journal| author=Molitch ME| title=Clinical manifestations of acromegaly. | journal=Endocrinol Metab Clin North Am | year= 1992 | volume= 21 | issue= 3 | pages= 597-614 | pmid=1521514 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1521514  }} </ref></div> }}
{{familytree | | | | | | | | | | | | | |!| | | | | | }}
{{familytree | | | | | | | | | | | | | |!| | | | | | }}
{{familytree | | | | | | | | | | | | | B01 | | | B01=<div style="float: left; text-align: left; width: 20em; padding:1em;">'''Examine the patient:'''<BR>❑ Enlargement of the hands and feet<BR>❑ Changes in facial appearance <br>❑ [[Visual disturbance]]<ref name="pmid1521514">{{cite journal| author=Molitch ME| title=Clinical manifestations of acromegaly. | journal=Endocrinol Metab Clin North Am | year= 1992 | volume= 21 | issue= 3 | pages= 597-614 | pmid=1521514 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1521514  }} </ref><BR> ❑ Abdominal exam:
{{familytree | | | | | | | | | | | | | B01 | | | B01=<div style="float: left; text-align: left; width: 20em; padding:1em;">'''Examine the patient:'''<BR>❑ Enlargement of the hands and feet<BR>❑ Changes in facial appearance (large bones of the face, large jaw and tongue, widely spaced teeth) <br>❑ [[Visual disturbance]]<ref name="pmid1521514">{{cite journal| author=Molitch ME| title=Clinical manifestations of acromegaly. | journal=Endocrinol Metab Clin North Am | year= 1992 | volume= 21 | issue= 3 | pages= 597-614 | pmid=1521514 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1521514  }} </ref>
*[[Splenomegaly|Enlarged spleen]]
<BR>❑ Musculoskeletal exam:
* RUQ pain may indicate bilirubin gallstones
* Joint pain
<BR>❑ Skin exam:
* Limited joint movement
* Pallor of nail beds, palmar creases
* Swelling of the bony areas around a joint <ref name="urlAcromegaly: MedlinePlus Medical Encyclopedia">{{cite web |url=https://medlineplus.gov/ency/article/000321.htm |title=Acromegaly: MedlinePlus Medical Encyclopedia |format= |work= |accessdate=}}</ref>
* Bronze skin colour in case of repeated transfusions
* Leg [[ulcer]]s
<BR>❑ [[Fever]] and neurological signs are seen in [[TTP]] <br>❑ [[Hemoglobinuria]] in some cases</div>}}
<BR>❑ [[Fever]] and neurological signs are seen in [[TTP]] <br>❑ [[Hemoglobinuria]] in some cases</div>}}
{{familytree | | | | | | | | | | | | | |!| | | | | | | }}
{{familytree | | | | | | | | | | | | | |!| | | | | | | }}

Revision as of 06:00, 20 August 2020

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Tayyaba Ali, M.D.[2]

Overview

This section provides a short and straight to the point overview of the disease or symptom. The first sentence of the overview must contain the name of the disease.

Causes

Life Threatening Causes

Life-threatening causes include conditions that may result in death or permanent disability within 24 hours if left untreated.

Common Causes

Diagnosis

The approach to diagnosis of Acromegaly is based on a step-wise testing strategy. Below is an algorithm summarising the identification and laboratory diagnosis of Acromegaly.

 
 
 
 
 
 
 
 
 
 
 
 
Characterize the symptoms:
Headaches
Lethargy
Hyperhidrosis (excessive sweating)
Lethargy
Paraesthesia
Sexual dysfunction[1]
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Examine the patient:
❑ Enlargement of the hands and feet
❑ Changes in facial appearance (large bones of the face, large jaw and tongue, widely spaced teeth)
Visual disturbance[1]


❑ Musculoskeletal exam:

  • Joint pain
  • Limited joint movement
  • Swelling of the bony areas around a joint [2]

Fever and neurological signs are seen in TTP
Hemoglobinuria in some cases
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Treatment

Shown below is an algorithm summarizing the treatment of [[disease name]] according the the [...] guidelines.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Do's

  • The content in this section is in bullet points.

Don'ts

  • The content in this section is in bullet points.

References

  1. 1.0 1.1 Molitch ME (1992). "Clinical manifestations of acromegaly". Endocrinol Metab Clin North Am. 21 (3): 597–614. PMID 1521514.
  2. "Acromegaly: MedlinePlus Medical Encyclopedia".


Template:WikiDoc Sources