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| == Diagnostic Study of Choice == | | == Diagnostic Study of Choice == |
| | | * Lymph node biopsy is the diagnostic study of choice. |
| === Study of choice ===
| | * The lymph node sample undergoes hostological examination. |
| [Name of the investigation] is the gold standard test for the diagnosis of [disease name].
| | * Immunohistochemistry, FISh and cytogenetic studies are also conducted on the tissue sample. |
| | | * Other diagnostic tests that are done are : |
| OR
| | ** [[Complete blood count]] (CBC) |
| | | ** Complete metabolic panel |
| The following result of [gold standard test] is confirmatory of [disease name]:
| | ** HBV, HCV and HIV testing |
| * [Result 1]
| | ** Serum LDH levels and serum β<sub>2</sub>-microglobulin levels. |
| * [Result 2]
| | ** Bone marrow biopsy and aspiration |
| | | ** Chest x ray and abdominal ultrasound |
| OR
| | ** CT scan |
| | | ** PET scan |
| [Name of the investigation] must be performed when:
| | ** Cytogenetics studies |
| * The patient presents with [symptom/sign 1], [symptom/sign 2], and [symptom/sign 3]. | | ** [[Flow cytometry]] |
| * A [name of test] is positive for [sign 1], [sign 2], and [sign 3] in the patient.
| | ** [[Immunohistochemistry]] |
| | | ** [[FISH]] |
| OR
| | ** [[Genetic testing]] |
| | | ** [[Immunophenotyping]]: [[BCL-2]]+, BCL6+, [[CD5]]-, CD10+, [[CD19]], [[CD20]], [[CD22]], [[CD43]], [[CD79a]], heavy and light chains rearranged, t(14;18)(q32:q21)-85% with rearrangement of ''[[BCL-2]]'' gene. |
| [Name of the investigation] is the gold standard test for the diagnosis of [disease name].
| | ** Endoscopy for gastrointestinal lymphoma |
| | |
| OR
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| The diagnostic study of choice for [disease name] is [name of the investigation].
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| OR
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| There is no single diagnostic study of choice for the diagnosis of [disease name].
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| OR
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| There is no single diagnostic study of choice for the diagnosis of [disease name], but [disease name] can be diagnosed based on [name of the investigation 1] and [name of the investigation 2].
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| OR
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| [Disease name] is primarily diagnosed based on the clinical presentation.
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| OR
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| Investigations:
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| * Among the patients who present with clinical signs of [disease name], the [investigation name] is the most specific test for the diagnosis. | |
| * Among the patients who present with clinical signs of [disease name], the [investigation name] is the most sensitive test for diagnosis. | |
| * Among the patients who present with clinical signs of [disease name], the [investigation name] is the most efficient test for diagnosis. | |
| | |
| ==== The comparison of various diagnostic studies for [disease name] ====
| |
| {|
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| |- style="background: #4479BA; color: #FFFFFF; text-align: center;"
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| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" | Test
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| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Sensitivity
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| ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Specificity
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| |-
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| ! style="background: #696969; color: #FFFFFF; text-align: center;" |Test 1
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| | style="background: #DCDCDC; padding: 5px; text-align: center;" |...%
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| | style="background: #DCDCDC; padding: 5px; text-align: center;" |...%
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| |-
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| ! style="background: #696969; color: #FFFFFF; text-align: center;" |Test 2
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| | style="background: #DCDCDC; padding: 5px; text-align: center;" |...%
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| | style="background: #DCDCDC; padding: 5px; text-align: center;" |...%
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| |}
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| <small> [Name of test with higher sensitivity and specificity] is the preferred investigation based on the sensitivity and specificity</small>
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| ===== Diagnostic results =====
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| The following finding(s) on performing [investigation name] is(are) confirmatory for [disease name]:
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| * [Finding 1] | |
| * [Finding 2]
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| ===== Sequence of Diagnostic Studies =====
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| The [name of investigation] must be performed when:
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| * The patient presented with symptoms/signs 1, 2, and 3 as the first step of diagnosis. | |
| * A positive [test] is detected in the patient, to confirm the diagnosis. | |
| | |
| OR
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| The various investigations must be performed in the following order:
| |
| * [Initial investigation] | |
| * [2nd investigation] | |
| | |
| === Name of Diagnostic Criteria ===
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| '''It is recommended that you include the criteria in a table. Make sure you always cite the source of the content and whether the table has been adapted from another source.'''
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| [Disease name] is primarily diagnosed based on clinical presentation. There are no established criteria for the diagnosis of [disease name]. | |
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| OR
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| There is no single diagnostic study of choice for [disease name], though [disease name] may be diagnosed based on [name of criteria] established by [...].
| |
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| OR
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| The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met: [criterion 1], [criterion 2], [criterion 3], and [criterion 4].
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| OR
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| The diagnosis of [disease name] is based on the [criteria name] criteria, which includes [criterion 1], [criterion 2], and [criterion 3].
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| OR
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| [Disease name] may be diagnosed at any time if one or more of the following criteria are met:
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| * Criteria 1
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| * Criteria 2
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| * Criteria 3
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| OR
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| '''IF there are clear, established diagnostic criteria'''
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| The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met: [criterion 1], [criterion 2], [criterion 3], and [criterion 4].
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| OR
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| The diagnosis of [disease name] is based on the [criteria name] criteria, which include [criterion 1], [criterion 2], and [criterion 3].
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| OR
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| The diagnosis of [disease name] is based on the [definition name] definition, which includes [criterion 1], [criterion 2], and [criterion 3].
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| OR
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| '''IF there are no established diagnostic criteria'''
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| There are no established criteria for the diagnosis of [disease name].
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| ==References== | | ==References== |