Human parainfluenza virus: Difference between revisions
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*Human parainfluenza viruses (HPIVs) are a group of four [[serotypes]] of enveloped, single stranded negative sense [[RNA]] viruses.<ref name = "ParaChar">{{cite journal |vauthors=Vainionpää R, Hyypiä T |title=Biology of parainfluenza viruses |journal=Clin. Microbiol. Rev. |volume=7 |issue=2 |pages=265–75 |year=1994 |pmid=8055470 |pmc=358320 |doi= |url=}}</ref> | *Human parainfluenza viruses (HPIVs) are a group of four [[serotypes]] of enveloped, single stranded negative sense [[RNA]] viruses.<ref name = "ParaChar">{{cite journal |vauthors=Vainionpää R, Hyypiä T |title=Biology of parainfluenza viruses |journal=Clin. Microbiol. Rev. |volume=7 |issue=2 |pages=265–75 |year=1994 |pmid=8055470 |pmc=358320 |doi= |url=}}</ref> | ||
*The human parainfluenza virus [[genome]] consists of approximately 15,000 [[nucleotides]] used to encode the following six structural proteins:.<ref name="Henrickson2003">{{cite journal|last1=Henrickson|first1=K. J.|title=Parainfluenza Viruses|journal=Clinical Microbiology Reviews|volume=16|issue=2|year=2003|pages=242–264|issn=0893-8512|doi=10.1128/CMR.16.2.242-264.2003}}</ref> | *The human parainfluenza virus [[genome]] consists of approximately 15,000 [[nucleotides]] used to encode the following six structural proteins:.<ref name="Henrickson2003">{{cite journal|last1=Henrickson|first1=K. J.|title=Parainfluenza Viruses|journal=Clinical Microbiology Reviews|volume=16|issue=2|year=2003|pages=242–264|issn=0893-8512|doi=10.1128/CMR.16.2.242-264.2003}}</ref> | ||
{| style="font-size: 85%;" | |||
! style="width: 110px; background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Protein}} | |||
! style="width: 110px; background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Location}} | |||
! style="width: 300px; background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Function}} | |||
|- | |||
| style="background: #DCDCDC; padding: 5px; text-align: center;" | '''[[Hemagglutinin|hemagglutinin]]''' | |||
| style="background: #F5F5F5; padding: 5px;" | Envelope | |||
| style="background: #F5F5F5; padding: 5px;" | Attachment and cell entry | |||
|- | |||
| style="background: #DCDCDC; padding: 5px; text-align: center;" | '''[[Fusion protein|fusion protein]]''' | |||
| style="background: #F5F5F5; padding: 5px;" | Envelope | |||
| style="background: #F5F5F5; padding: 5px;" | Fusion and cell entry | |||
|- | |||
| style="background: #DCDCDC; padding: 5px; text-align: center;" | '''[[Matrix protein|matrix protein]]''' | |||
| style="background: #F5F5F5; padding: 5px;" | Within the envelope | |||
| style="background: #F5F5F5; padding: 5px;" | Assembly | |||
|- | |||
| style="background: #DCDCDC; padding: 5px; text-align: center;" | '''[[Nucleoprotein|nucleoprotein]]''' | |||
| style="background: #F5F5F5; padding: 5px;" | [[Nucleocapsid]] | |||
| style="background: #F5F5F5; padding: 5px;" | Forms a complex with the [[RNA]] [[Genome|genome]] | |||
|- | |||
| style="background: #DCDCDC; padding: 5px; text-align: center;" | '''[[Phosphoprotein|phosphoprotein]]''' | |||
| style="background: #F5F5F5; padding: 5px;" | [[Nucleocapsid]] | |||
| style="background: #F5F5F5; padding: 5px;" | Forms as a part of the [[RNA polymerase]] complex | |||
|- | |||
| style="background: #DCDCDC; padding: 5px; text-align: center;" | '''[[RNA polymerase|large protein]]''' | |||
| style="background: #F5F5F5; padding: 5px;" | [[Nucleocapsid]] | |||
| style="background: #F5F5F5; padding: 5px;" | Forms as a part of the [[RNA polymerase]] complex | |||
|} | |||
==References== | ==References== |
Revision as of 17:23, 27 January 2016
Croup Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Human parainfluenza virus On the Web |
American Roentgen Ray Society Images of Human parainfluenza virus |
Risk calculators and risk factors for Human parainfluenza virus |
Human parainfluenza virus | ||||||
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A Transmission Electron Micrograph (TEM) depicting parainfluenza virions, and free filamentous nucleocapsid material.
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Virus classification | ||||||
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This page is about microbiologic aspects of the organism(s). For clinical aspects of the disease, see Croup.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.
Overview
Microbiological Characteristics
- Human parainfluenza viruses (HPIVs) are a group of four serotypes of enveloped, single stranded negative sense RNA viruses.[1]
- The human parainfluenza virus genome consists of approximately 15,000 nucleotides used to encode the following six structural proteins:.[2]
Protein | Location | Function |
---|---|---|
hemagglutinin | Envelope | Attachment and cell entry |
fusion protein | Envelope | Fusion and cell entry |
matrix protein | Within the envelope | Assembly |
nucleoprotein | Nucleocapsid | Forms a complex with the RNA genome |
phosphoprotein | Nucleocapsid | Forms as a part of the RNA polymerase complex |
large protein | Nucleocapsid | Forms as a part of the RNA polymerase complex |