Glioma classification: Difference between revisions
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==Overview== | ==Overview== | ||
Glioma may be classified into several subtypes based on the type of cell, grade, and location. | Glioma may be classified into several subtypes based on the type of cell, grade, and location.<ref>Classification of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma</ref> | ||
==Classification== | ==Classification== | ||
Glioma may be classified into several subtypes based on the type of cell, grade, and location. | Glioma may be classified into several subtypes based on the type of cell, grade, and location.<ref>Classification of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma</ref> | ||
===1. Based on the type of cell=== | ===1. Based on the type of cell=== | ||
Glioma may be classified according to the type of cell into four subtypes: | Glioma may be classified according to the type of cell into four subtypes:<ref>Classification of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma</ref> | ||
* [[Ependymoma]]s — [[ependymal cell]]s | * [[Ependymoma]]s — [[ependymal cell]]s | ||
* [[Astrocytoma]]s — [[astrocyte]]s | * [[Astrocytoma]]s — [[astrocyte]]s | ||
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===2. Based on the grade=== | ===2. Based on the grade=== | ||
Glioma may be classified according to the grade into two subtypes: | Glioma may be classified according to the grade into two subtypes:<ref>Classification of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma</ref> | ||
*Low-grade gliomas are well-differentiated tumors. These are [[cancer|benign]] tumors. | *Low-grade gliomas are well-differentiated tumors. These are [[cancer|benign]] tumors. | ||
*High-grade gliomas are undifferentiated or [[anaplastic]] tumors. These are [[cancer|malignant]] tumors. | *High-grade gliomas are undifferentiated or [[anaplastic]] tumors. These are [[cancer|malignant]] tumors. | ||
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===3. Based on the location=== | ===3. Based on the location=== | ||
Glioma may be classified according to the location into two subtypes: | Glioma may be classified according to the location into two subtypes:<ref>Classification of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma</ref> | ||
* [[Infratentorial]] : mostly in children (70%) | * [[Infratentorial]] : mostly in children (70%) | ||
* [[Supratentorial]] : mostly in adults (70%) | * [[Supratentorial]] : mostly in adults (70%) |
Revision as of 03:30, 20 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]Sujit Routray, M.D. [3]
Overview
Glioma may be classified into several subtypes based on the type of cell, grade, and location.[1]
Classification
Glioma may be classified into several subtypes based on the type of cell, grade, and location.[2]
1. Based on the type of cell
Glioma may be classified according to the type of cell into four subtypes:[3]
- Ependymomas — ependymal cells
- Astrocytomas — astrocytes
- Oligodendrogliomas — oligodendrocytes
- Mixed gliomas, such as oligoastrocytomas, contain cells from different types of glia.
2. Based on the grade
Glioma may be classified according to the grade into two subtypes:[4]
- Low-grade gliomas are well-differentiated tumors. These are benign tumors.
- High-grade gliomas are undifferentiated or anaplastic tumors. These are malignant tumors.
WHO grading system for astrocytomas
- WHO Grade 1 — e.g., pilocytic astrocytoma
- WHO Grade 2 — e.g., diffuse or low-grade astrocytoma
- WHO Grade 3 — e.g., anaplastic (malignant) astrocytoma
- WHO Grade 4 — e.g., glioblastoma multiforme
3. Based on the location
Glioma may be classified according to the location into two subtypes:[5]
- Infratentorial : mostly in children (70%)
- Supratentorial : mostly in adults (70%)
References
- ↑ Classification of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma
- ↑ Classification of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma
- ↑ Classification of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma
- ↑ Classification of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma
- ↑ Classification of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma