Transposition of the great vessels epidemiology and demographics: Difference between revisions

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==Epidemiology and demographics==
{{CMG}}; '''Associate Editor(s)-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.B.B.S.]] [mailto:psingh13579@gmail.com]; {{CZ}}; [[User:KeriShafer|Keri Shafer, M.D.]] [mailto:kshafer@bidmc.harvard.edu]; [[Kristin Feeney|Kristin Feeney, B.S.]] [mailto:kfeeney@elon.edu]
Transposition of the great arteries TGA is one of the most common cyanotic congenital heart defects present in the first 24 hours of life. TGA represents 5-7% of all CHD with an incidence at birth of 20-30 in 100000 live births. TGA is more common in infants of diabetic mothers. Boys outnumber girls with an approximate ratio of 2:1.  Without treatment, 30% of infants die within the first week of life, 50% will die in the first month, 70% will die in the first 6 months and 90% of infants will die before the end of the first year. 4.9% of patients have associated extracardiac abnormalities.
 
==Overview==
The prevalence of TPA is approximately 47 per 100,000 individuals worldwide. TGA accounts for 5-7 percent of all congenital heart disease and 20 percent of [[Congenital heart disease cyanotic|cyanotic heart disease]]. There is no racial predilection to transposition of great vessels. Transposition of the great arteries has a 60-70% male predominance.
 
==Epidemiology ==
===Incidence===
*Transposition of the great arteries TGA is one of the commonest cyanotic congenital heart defects present in the '''first 24 hours of life'''.<ref name="pmid16397457">{{cite journal |vauthors= |title=Improved national prevalence estimates for 18 selected major birth defects--United States, 1999-2001 |journal=MMWR Morb. Mortal. Wkly. Rep. |volume=54 |issue=51 |pages=1301–5 |date=January 2006 |pmid=16397457 |doi= |url=}}</ref>
*The overall annual incidence of TGA is 20-30 per 100,000 live births.
*TGA represents 5-7% of all congenital heart disease and 20% of cyanotic disease.
 
== Demographics ==
 
===Gender===
*Boys outnumber girls with an approximate ratio of 2:1.   
 
=== Race ===
 
* There is no racial predilection to transposition of great vessels.


==References==
==References==
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[[fr:Transposition des gros vaisseaux]]
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[[zh:大血管轉位]]
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[[Category:DiseaseState]]
[[Category:Cardiology]]
[[Category:Cardiology]]
[[Category:Congenital heart disease]]
[[Category:Congenital heart disease]]
 
[[Category:Genetic Disease]]
[[Category:Disease]]
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Latest revision as of 17:29, 21 February 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3]; Keri Shafer, M.D. [4]; Kristin Feeney, B.S. [5]

Overview

The prevalence of TPA is approximately 47 per 100,000 individuals worldwide. TGA accounts for 5-7 percent of all congenital heart disease and 20 percent of cyanotic heart disease. There is no racial predilection to transposition of great vessels. Transposition of the great arteries has a 60-70% male predominance.

Epidemiology

Incidence

  • Transposition of the great arteries TGA is one of the commonest cyanotic congenital heart defects present in the first 24 hours of life.[1]
  • The overall annual incidence of TGA is 20-30 per 100,000 live births.
  • TGA represents 5-7% of all congenital heart disease and 20% of cyanotic disease.

Demographics

Gender

  • Boys outnumber girls with an approximate ratio of 2:1.

Race

  • There is no racial predilection to transposition of great vessels.

References

  1. "Improved national prevalence estimates for 18 selected major birth defects--United States, 1999-2001". MMWR Morb. Mortal. Wkly. Rep. 54 (51): 1301–5. January 2006. PMID 16397457.

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