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{{Cardiac tumors}}
{{Cardiac tumors}}
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==Overview==
==Overview==
* Numerous genetic disorders are associated with cardiac tumors however, till now no direct causes have been identified.
==Causes==
==Causes==


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Latest revision as of 16:26, 14 July 2022

Cardiac tumors Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Cardiac Tumors from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

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Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Cardiac tumors causes On the Web

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Risk calculators and risk factors for Cardiac tumors causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dheeraj Makkar, M.D.[2]

Overview

  • Numerous genetic disorders are associated with cardiac tumors however, till now no direct causes have been identified.

Causes

  • Many genetic conditions are strongly associated with a large number of heart tumors. Some of them are as follows:[1]
Cardiac tumors genetic causes
Tumor Syndrome Gene Associated with syndrome
Rhabdomyoma Tuberous Sclerosis TSC1 or hamartin

TSC2 or tuberin

Fibroma Gorlin Syndrome PATCHED gene
Myxoma Carney Complex Inactivating mutation of PRKARA1A

Activating pathogenic variant of PRKACA gene

Paraganglioma Carney triad No known gene associations
Paraganglioma Hereditary Paraganglioma Mutation of succinate dehydrogenase subunit

SDHAF2 gene, and possibly MAX gene but these mutations are rare

Paraganglioma Von Hippel Lindau VHL gene
Paraganglioma Neurofibromatosis type 1 NF1 gene


References

  1. Lee E, Mahani MG, Lu JC, Dorfman AL, Srinivasan A, Agarwal PP (2018). "Primary cardiac tumors associated with genetic syndromes: a comprehensive review". Pediatr Radiol. 48 (2): 156–164. doi:10.1007/s00247-017-4027-2. PMID 29214333.

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