Neuroblastoma physical examination: Difference between revisions

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{{CMG}} {{AE}}{{ZAS}}{{HL}}
{{CMG}} {{AE}}{{ZAS}}{{HL}}
==Overview==
==Overview==
A positive finding of a palpable [[abdominal mass]], [[fever]], and purple skin patches is suggestive of neuroblastoma
[[Physical examination]] findings of neuroblastoma include; [[fever]], [[hypertension]], [[tachycardia]], [[pallor]], [[ecchymoses]], [[nystagmus]], [[proptosis]], [[ptosis]], [[abdominal mass]], brisk reflexes, [[sensory loss]] and [[ataxia]].


==Physical Examination==
==Physical Examination==
===General Appearance===
===General Appearance===
* Neuroblastoma patients often appear fatigued.<ref name="O"> Neuroblastoma Childhood: Symptoms and Signs. Cancer.net http://www.cancer.net/cancer-types/neuroblastoma-childhood/symptoms-and-signs Accessed on October, 7 2015</ref><ref name="gov"> Neuroblastoma Treatment for health professionals. National Cancer Institute (2015) http://www.cancer.gov/types/neuroblastoma/hp/neuroblastoma-treatment-pdq#link/_534_toc Accessed on October, 7 2015</ref><ref name="pmid21736987">{{cite journal| author=Colon NC, Chung DH| title=Neuroblastoma. | journal=Adv Pediatr | year= 2011 | volume= 58 | issue= 1 | pages= 297-311 | pmid=21736987 | doi=10.1016/j.yapd.2011.03.011 | pmc=PMC3668791 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21736987  }} </ref>
* Neuroblastoma [[Patient|patients]] often appear [[Fatigue|fatigued]].<ref name="O">Neuroblastoma Childhood: Symptoms and Signs. Cancer.net http://www.cancer.net/cancer-types/neuroblastoma-childhood/symptoms-and-signs Accessed on October, 7 2015</ref><ref name="gov">Neuroblastoma Treatment for health professionals. National Cancer Institute (2015) http://www.cancer.gov/types/neuroblastoma/hp/neuroblastoma-treatment-pdq#link/_534_toc Accessed on October, 7 2015</ref><ref name="pmid21736987">{{cite journal| author=Colon NC, Chung DH| title=Neuroblastoma. | journal=Adv Pediatr | year= 2011 | volume= 58 | issue= 1 | pages= 297-311 | pmid=21736987 | doi=10.1016/j.yapd.2011.03.011 | pmc=PMC3668791 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21736987  }} </ref><ref>{{Cite journal
| author = [[J. W. Duckett]] & [[C. E. Koop]]
| title = Neuroblastoma
| journal = [[The Urologic clinics of North America]]
| volume = 4
| issue = 2
| pages = 285–295
| year = 1977
| month = June
| pmid = 331618
}}</ref><ref>{{Cite journal
| author = [[Nadja C. Colon]] & [[Dai H. Chung]]
| title = Neuroblastoma
| journal = [[Advances in pediatrics]]
| volume = 58
| issue = 1
| pages = 297–311
| year = 2011
| month =
| doi = 10.1016/j.yapd.2011.03.011
| pmid = 21736987
}}</ref><ref>{{Cite journal
| author = [[John M. Maris]]
| title = Recent advances in neuroblastoma
| journal = [[The New England journal of medicine]]
| volume = 362
| issue = 23
| pages = 2202–2211
| year = 2010
| month = June
| doi = 10.1056/NEJMra0804577
| pmid = 20558371
}}</ref>


===Vital Signs===
===Vital Signs===
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* Periorbital [[ecchymosis]]
* Periorbital [[ecchymosis]]
* Visual defects
* Visual defects
* Conjuctival [[pallor]]
* [[Conjuctiva|Conjuctival]] [[pallor]]
* [[Nystagmus]]
* [[Nystagmus]]
* [[Proptosis]]
* [[Proptosis]]
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===Skeletal===
===Skeletal===
* Sudden [[muscle]] jerks
* Sudden [[muscle]] jerks
* [[Bone]] tenderness
* [[Bone]] [[tenderness]]


===CNS===
===CNS===
* Motor weakness
* Motor [[weakness]]
* [[Sensory loss]]
* [[Sensory loss]]
* [[Paralysis]]
* [[Paralysis]]

Latest revision as of 16:01, 4 March 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Zahir Ali Shaikh, MD[2]Haytham Allaham, M.D. [3]

Overview

Physical examination findings of neuroblastoma include; fever, hypertension, tachycardia, pallor, ecchymoses, nystagmus, proptosis, ptosis, abdominal mass, brisk reflexes, sensory loss and ataxia.

Physical Examination

General Appearance

Vital Signs

Skin

HEENT

Abdomen

Skeletal

CNS

References

  1. Neuroblastoma Childhood: Symptoms and Signs. Cancer.net http://www.cancer.net/cancer-types/neuroblastoma-childhood/symptoms-and-signs Accessed on October, 7 2015
  2. Neuroblastoma Treatment for health professionals. National Cancer Institute (2015) http://www.cancer.gov/types/neuroblastoma/hp/neuroblastoma-treatment-pdq#link/_534_toc Accessed on October, 7 2015
  3. Colon NC, Chung DH (2011). "Neuroblastoma". Adv Pediatr. 58 (1): 297–311. doi:10.1016/j.yapd.2011.03.011. PMC 3668791. PMID 21736987.
  4. J. W. Duckett & C. E. Koop (1977). "Neuroblastoma". The Urologic clinics of North America. 4 (2): 285–295. PMID 331618. Unknown parameter |month= ignored (help)
  5. Nadja C. Colon & Dai H. Chung (2011). "Neuroblastoma". Advances in pediatrics. 58 (1): 297–311. doi:10.1016/j.yapd.2011.03.011. PMID 21736987.
  6. John M. Maris (2010). "Recent advances in neuroblastoma". The New England journal of medicine. 362 (23): 2202–2211. doi:10.1056/NEJMra0804577. PMID 20558371. Unknown parameter |month= ignored (help)

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