Neuroblastoma MRI
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Zahir Ali Shaikh, MD[2]Haytham Allaham, M.D. [3]
Overview
MRI is considered the most useful modality in staging of neuroblastoma. It is superior to CT scan when determining marrow infiltration and intra spinal tumor extension.MRI findings in neuroblastoma patients include; hypointense heterogeneous mass on T1 weighted image, heterogeneous/hyperintense enhancement due to necrosis and cyst formation seen on T2 weighted images.
MRI
- MRI has been considered the most useful modality in staging of neuroblastoma in recent years.[1][2][3]
- MRI is superior to CT scan when determining marrow infiltration and intra spinal tumor extension.[4]
- The advantages of MRI include lack of ionizing radiation and no necessity of using oral contrast.
- MRI findings observed among neuroblastoma patients include:[5][6]
- T1 weighted image demonstrates:
- Hypointense heterogeneous mass
- T1 weighted image with gadolinium contrast demonstrates:
- Heterogeneous variable enhancement
- T2 weighted image demonstrates:
- Heterogeneous/hyperintense enhancement due necrosis and cyst formation
Gallery
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Neuroblastoma observed on coronal MRI of the abdomen as a well defined mass lesion located at the right suprarenal region[5]
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Neuroblastoma observed on sagittal MRI as a large mass which extends into the spinal canal and causes significant cord compression[5]
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Neuroblastoma observed on transverse MRI as a large mass which extends into the spinal canal and causes significant cord compression[5]
References
- ↑ Georgia Papaioannou & Kieran McHugh (2005). "Neuroblastoma in childhood: review and radiological findings". Cancer imaging : the official publication of the International Cancer Imaging Society. 5: 116–127. doi:10.1102/1470-7330.2005.0104. PMID 16305949. Unknown parameter
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ignored (help) - ↑ Brian H. Kushner (2004). "Neuroblastoma: a disease requiring a multitude of imaging studies". Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 45 (7): 1172–1188. PMID 15235064. Unknown parameter
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ignored (help) - ↑ Gael J. Lonergan, Cornelia M. Schwab, Eric S. Suarez & Christian L. Carlson (2002). "Neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: radiologic-pathologic correlation". Radiographics : a review publication of the Radiological Society of North America, Inc. 22 (4): 911–934. doi:10.1148/radiographics.22.4.g02jl15911. PMID 12110723. Unknown parameter
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ignored (help) - ↑ Georgia Papaioannou & Kieran McHugh (2005). "Neuroblastoma in childhood: review and radiological findings". Cancer imaging : the official publication of the International Cancer Imaging Society. 5: 116–127. doi:10.1102/1470-7330.2005.0104. PMID 16305949. Unknown parameter
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ignored (help) - ↑ 5.0 5.1 5.2 5.3 Neuroblastoma. Radiopaedia (2015) http://radiopaedia.org/articles/neuroblastoma Accessed on October, 4 2015
- ↑ Maureen Dumba, Noorulhuda Jawad & Kieran McHugh (2015). "Neuroblastoma and nephroblastoma: a radiological review". Cancer imaging : the official publication of the International Cancer Imaging Society. 15: 5. doi:10.1186/s40644-015-0040-6. PMID 25889326. Unknown parameter
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ignored (help)