Zollinger-Ellison syndrome ultrasound: Difference between revisions

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{{CMG}} {{AE}} {{MJK}}
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==Overview==
==Overview==
Abdominal [[ultrasound]] may be helpful in the diagnosis of Zollinger-Ellison syndrome caused by [[gastrinoma]].<ref name="HarveyPasieka2012">{{cite journal|last1=Harvey|first1=Adrian|last2=Pasieka|first2=Janice L.|last3=Al-Bisher|first3=Hassan|last4=Dixon|first4=Elijah|title=Primary Hepatic Gastrinoma Causing Zollinger-Ellison Syndrome: A Rare and Challenging Diagnosis|journal=Cancers|volume=4|issue=4|year=2012|pages=130–140|issn=2072-6694|doi=10.3390/cancers4010130}}</ref>
Abdominal [[ultrasound]] may be helpful in the diagnosis of Zollinger-Ellison syndrome caused by [[gastrinoma]].<ref name="HarveyPasieka2012">{{cite journal|last1=Harvey|first1=Adrian|last2=Pasieka|first2=Janice L.|last3=Al-Bisher|first3=Hassan|last4=Dixon|first4=Elijah|title=Primary Hepatic Gastrinoma Causing Zollinger-Ellison Syndrome: A Rare and Challenging Diagnosis|journal=Cancers|volume=4|issue=4|year=2012|pages=130–140|issn=2072-6694|doi=10.3390/cancers4010130}}</ref>. [[Ultrasonography]] can detect [[gastrinoma]]<nowiki/>s in 30%. [[Endoscopic]] ultrasonography (EUS) is a highly [[Sensitivity (tests)|sensitive]] and [[specificity|specific]] procedure for the localization of [[pancreatic]] endocrine tumors and [[duodenal]] as well as [[pancreatic]] gastrinomas.


==Abdominal Ultrasound==
==Abdominal Ultrasound==
Abdominal [[ultrasound]] may be helpful in the diagnosis of Zollinger-Ellison syndrome caused by [[gastrinoma]].
*I<nowiki/>n 30% of cases [[Ultrasonography]] can detect [[gastrinoma]]<nowiki/>s and the detection rates are better for lesions greater than 3 cm in diameter and are poor for lesions smaller than 1 cm. <ref name="pmid1994415">{{cite journal| author=London JF, Shawker TH, Doppman JL, Frucht HH, Vinayek R, Stark HA et al.| title=Zollinger-Ellison syndrome: prospective assessment of abdominal US in the localization of gastrinomas. | journal=Radiology | year= 1991 | volume= 178 | issue= 3 | pages= 763-7 | pmid=1994415 | doi=10.1148/radiology.178.3.1994415 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1994415  }} </ref>
*[[Endoscopic]] ultrasonography (EUS) is a highly [[Sensitivity (tests)|sensitive]] and [[specificity|specific]] procedure for the localization of [[pancreatic]] [[neuroendocrine tumors]] and should be considered for the preoperative localization of such tumors once the clinical and laboratory diagnosis has been established. <ref name="pmid1317506">{{cite journal| author=Rösch T, Lightdale CJ, Botet JF, Boyce GA, Sivak MV, Yasuda K et al.| title=Localization of pancreatic endocrine tumors by endoscopic ultrasonography. | journal=N Engl J Med | year= 1992 | volume= 326 | issue= 26 | pages= 1721-6 | pmid=1317506 | doi=10.1056/NEJM199206253262601 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1317506  }} </ref>
*[[Endoscopy]] or EUS should also be performed when a [[gastrinoma]] is suspected in order to identify duodenal as well as [[pancreatic]] [[gastrinomas]], especially when multiple lesions are suspected as in [[MEN 1]]. <ref name="pmid11762360">{{cite journal| author=Tomassetti P, Migliori M, Lalli S, Campana D, Tomassetti V, Corinaldesi R| title=Epidemiology, clinical features and diagnosis of gastroenteropancreatic endocrine tumours. | journal=Ann Oncol | year= 2001 | volume= 12 Suppl 2 | issue=  | pages= S95-9 | pmid=11762360 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11762360  }} </ref> <ref name="pmid9113315">{{cite journal| author=Jensen RT| title=Gastrointestinal endocrine tumours. Gastrinoma. | journal=Baillieres Clin Gastroenterol | year= 1996 | volume= 10 | issue= 4 | pages= 603-43 | pmid=9113315 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9113315  }} </ref>
 
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Latest revision as of 16:47, 11 October 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]

Overview

Abdominal ultrasound may be helpful in the diagnosis of Zollinger-Ellison syndrome caused by gastrinoma.[1]. Ultrasonography can detect gastrinomas in 30%. Endoscopic ultrasonography (EUS) is a highly sensitive and specific procedure for the localization of pancreatic endocrine tumors and duodenal as well as pancreatic gastrinomas.

Abdominal Ultrasound

References

  1. Harvey, Adrian; Pasieka, Janice L.; Al-Bisher, Hassan; Dixon, Elijah (2012). "Primary Hepatic Gastrinoma Causing Zollinger-Ellison Syndrome: A Rare and Challenging Diagnosis". Cancers. 4 (4): 130–140. doi:10.3390/cancers4010130. ISSN 2072-6694.
  2. London JF, Shawker TH, Doppman JL, Frucht HH, Vinayek R, Stark HA; et al. (1991). "Zollinger-Ellison syndrome: prospective assessment of abdominal US in the localization of gastrinomas". Radiology. 178 (3): 763–7. doi:10.1148/radiology.178.3.1994415. PMID 1994415.
  3. Rösch T, Lightdale CJ, Botet JF, Boyce GA, Sivak MV, Yasuda K; et al. (1992). "Localization of pancreatic endocrine tumors by endoscopic ultrasonography". N Engl J Med. 326 (26): 1721–6. doi:10.1056/NEJM199206253262601. PMID 1317506.
  4. Tomassetti P, Migliori M, Lalli S, Campana D, Tomassetti V, Corinaldesi R (2001). "Epidemiology, clinical features and diagnosis of gastroenteropancreatic endocrine tumours". Ann Oncol. 12 Suppl 2: S95–9. PMID 11762360.
  5. Jensen RT (1996). "Gastrointestinal endocrine tumours. Gastrinoma". Baillieres Clin Gastroenterol. 10 (4): 603–43. PMID 9113315.

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